7VR0: Human Serum Albumin

Human Serum Albumin. Determined by X-ray diffraction at 1.98 Å resolution. Released 26 Oct 2022.

Method: X-ray diffraction
Resolution: 1.98 Å
Organism: Homo sapiens
Chains: 1
Atoms: 4,863
Mol. weight: 66.57 kDa
Released: 26 Oct 2022

Explore 7VR0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7VR0 contains 39 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 39 helices, 0 β-strands

Element	Residues	Length
α-helix	6-14	9
α-helix	16-30	15
α-helix	36-55	20
α-helix	66-74	9
α-helix	90-92	3
α-helix	97-104	8
α-helix	120-129	10
α-helix	131-145	15
α-helix	151-168	18
α-helix	174-201	28
α-helix	202-206	5
α-helix	208-222	15
α-helix	228-246	19
α-helix	250-266	17
α-helix	268-270	3
α-helix	278-280	3
α-helix	283-290	8
α-helix	293-299	7
α-helix	302-304	3
α-helix	306	1
α-helix	307-311	5
α-helix	315-321	7
α-helix	323-336	14
α-helix	343-360	18
α-helix	366-370	5
α-helix	373-376	4
α-helix	377-414	38
α-helix	420-433	14
α-helix	434-438	5
α-helix	442-444	3
α-helix	445-465	21
α-helix	471-479	9
α-helix	481-483	3
α-helix	484-490	7
α-helix	497-502	6
α-helix	511-515	5
α-helix	518-535	18
α-helix	541-559	19
α-helix	566-581	16

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Serum albumin	A	protein	585	Homo sapiens	P02768 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>7VR0_1 Serum albumin (chains A)
DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAE
NCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEV
DVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLP
KLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTK
VHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPA
DLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKC
CAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVST
PTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES
LVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKAT
KEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

Primary citation

Human Serum Albumin. Xiang, W., Yue, Z.L., Su, J.Y. To be published.

Other PDB entries of the same protein (UniProt P02768 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9IK6 1.69 Å, Human Serum Albumin crystallized with T4, pH 6.5
6YG9 1.89 Å, Crystal structure of human serum albumin (HSA) in complex with gn-07.
1N5U 1.9 Å, X-ray study of human serum albumin complexed with heme
8RCO 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid II at 1.9 A resolution
8RCP 1.9 Å, Structure of Human Serum Albumin in complex with Myristic Acid
8RGK 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid at 1.9 A resolution
8RGL 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid I at 1.9 A resolution…
9EOD 1.9 Å, Human serum albumin with adamantene carboxylic acid
9CSG 1.91 Å, Human Serum Albumin Bound to Cerastecin Compound 5e
6QIO 1.95 Å, Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the…
9IK7 1.97 Å, Human Serum Albumin crystallized with T4, pH 7.5
7Y2D 2.0 Å, HSA-Cu agent complex

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