1HBW: Regulatory protein GAL4

Name: PDB 1HBW: Solution nmr structure of the dimerization domain of the yeast transcriptional activator Gal4 (residues 50-106)
Published: 2001-05-10
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: transcriptional activator

Solution nmr structure of the dimerization domain of the yeast transcriptional activator Gal4 (residues 50-106). Determined by solution NMR. Released 10 May 2001.

Method: Solution NMR
Organism: SACCHAROMYCES CEREVISIAE
Chains: 2
Atoms: 938
Mol. weight: 13.39 kDa
Released: 10 May 2001

Explore 1HBW in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1HBW contains 6 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chains A and B: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	55-67	13
α-helix	79-84	6
α-helix	88-96	9

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Regulatory protein GAL4	A, B	protein	57	SACCHAROMYCES CEREVISIAE	P04386 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>1HBW_1 REGULATORY PROTEIN GAL4 (chains A, B)
TRAHLTEVESRLERLEQLFLLIFPREDLDMILKMDSLRDIEALLTGLFVQDNVNKDA

Primary citation

Recruitment of the Transcriptional Machinery Through Gal11P: Structure and Interactions of the GAL4 Dimerization Domain. Hidalgo, P., Ansari, A.Z., Schmidt, P. et al. Genes Dev (2001) 15:1007. DOI 10.1101/GAD.873901 · PubMed

Other PDB entries of the same protein (UniProt P04386 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3COQ 2.4 Å, Structural Basis for Dimerization in DNA Recognition by Gal4
1D66 2.7 Å, DNA recognition by GAL4: structure of a protein/dna complex
3BTS 2.7 Å, Crystal structure of a ternary complex of the transcriptional repressor Gal80p (Gal80S0…
7UIO 3.3 Å, Mediator-PIC Early (Composite Model)
7UIK 7.7 Å, Mediator-PIC Early (Tail A + Upstream DNA & Activator)
1AW6 GAL4 (CD), NMR, 24 structures

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