1P9A: Platelet glycoprotein Ib alpha chain precursor

Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution. Determined by X-ray diffraction at 1.7 Å resolution. Released 22 Jul 2003.

Method
X-ray diffraction
Resolution
1.7 Å
Organism
Homo sapiens
Chains
1
Atoms
2,334
Mol. weight
33.06 kDa
Released
22 Jul 2003

Explore 1P9A in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1P9A contains 6 α-helices and 17 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain G: 6 helices, 17 β-strands

ElementResiduesLengthSheet
β-strand5-731
β-strand14-1631
β-strand35-3731
β-strand45-4732
α-helix48-514
β-strand59-6131
β-strand69-7132
β-strand81-8331
β-strand104-10631
β-strand128-13031
β-strand152-15431
β-strand176-17831
β-strand199-20131
β-strand20713
α-helix211-2133
α-helix214-2229
α-helix224-2263
β-strand22711
α-helix243-2453
β-strand24714
β-strand24813
β-strand25514
α-helix256-2583

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Platelet glycoprotein Ib alpha chain precursorGprotein290Homo sapiensP07359 (AlphaFold model)
Sequence of entity 1 (G), FASTA
>1P9A_1 Platelet glycoprotein Ib alpha chain precursor (chains G)
HPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQL
NLDRAELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGAL
RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ
ENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMT
SNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDTEGDKVR

Primary citation

Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. Celikel, R., McClintock, R.A., Roberts, J.R. et al. Science (2003) 301:218-221. DOI 10.1126/science.1084183 · PubMed

Other PDB entries of the same protein (UniProt P07359 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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