1X66: PDB entry 1X66

Solution structure of the SAM_PNT-domain of the human friend LEUKEMIAINTEGRATION 1 transcription factor. Determined by solution NMR. Released 17 Nov 2005.

Method: Solution NMR
Organism: Homo sapiens
Chains: 1
Atoms: 780
Mol. weight: 11.14 kDa
Released: 17 Nov 2005

Explore 1X66 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1X66 contains 7 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 7 helices, 0 β-strands

Element	Residues	Length
α-helix	10-12	3
α-helix	24-26	3
α-helix	31-42	12
α-helix	50-53	4
α-helix	58-63	6
α-helix	66-70	5
α-helix	75-89	15

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Friend leukemia integration 1 transcription factor	A	protein	98	Homo sapiens	Q01543 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>1X66_1 Friend leukemia integration 1 transcription factor (chains A)
GSSGSSGPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKE
LCKMNKEDFLRATTLYNTEVLLSHLSYLRESSSGPSSG

Primary citation

Solution structure of the SAM_PNT-domain of the human friend LEUKEMIAINTEGRATION 1 transcription factor. Goroncy, A., Kigawa, T., Koshiba, S. et al. To be published.

Other PDB entries of the same protein (UniProt Q01543 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9CP6 1.66 Å, Crystal structure of the DNA binding domain of FLI1 (residues 259-371)
9MX9 2.55 Å, Crystal structure of the DNA binding domain of FLI1 (F362A) in complex with a DNA…
9MXA 2.59 Å, Crystal structure of the DNA binding domain of FLI1 (wild-type) in complex with a DNA…
5E8G 2.7 Å, Crystal structure of the DNA binding domain of human transcription factor FLI1
5JVT 3.1 Å, Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with…
9MX8 3.15 Å, Crystal structure of the DNA binding domain of FLI1 in complex with a DNA containing…
9MWY 3.28 Å, Crystal structure of the DNA binding domain of FLI1 in complex with a DNA containing…
5E8I 3.45 Å, Crystal structure of the DNA binding domain of human transcription factor FLI1 in…
6VG2 3.9 Å, Crystal structure of the DNA binding domain of human transcription factor FLI1 in…
6VGD 4.2 Å, Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the…
6VG8 4.31 Å, Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with…
1FLI DNA-binding domain of fli-1

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