2KT1: PDB entry 2KT1

Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E. Determined by solution NMR. Released 26 Jan 2010.

Method
Solution NMR
Organism
Homo sapiens
Chains
1
Atoms
642
Mol. weight
9.96 kDa
Released
26 Jan 2010

Explore 2KT1 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2KT1 contains 2 α-helices and 8 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 2 helices, 8 β-strands

ElementResiduesLengthSheet
β-strand6-1161
β-strand1512
β-strand2211
β-strand2512
β-strand30-3451
α-helix35-417
α-helix51-544
β-strand56-6161
β-strand67-7151
β-strand75-8171

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Phosphatidylinositol 3-kinase regulatory subunit betaAprotein88Homo sapiensO00459 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>2KT1_1 Phosphatidylinositol 3-kinase regulatory subunit beta (chains A)
MAGPEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGGERCPQSVGWMPGL
NERTRQRGDFPGTYVEFLGPLEHHHHHH

Primary citation

Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E. Aramini, J.M., Ma, L., Schauder, C. et al. To be published.

Other PDB entries of the same protein (UniProt O00459 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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