2QKU: The 5th PDZ Domain of InaD in 10mM DTT

The 5th PDZ Domain of InaD in 10mM DTT. Determined by X-ray diffraction at 2.2 Å resolution. Released 6 Nov 2007.

Method: X-ray diffraction
Resolution: 2.2 Å
Organism: Drosophila melanogaster
Chains: 3
Atoms: 2,265
Mol. weight: 29.6 kDa
Released: 6 Nov 2007

Explore 2QKU in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2QKU contains 8 α-helices and 19 β-strands across 3 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 2 helices, 6 β-strands

Element	Residues	Length	Sheet
β-strand	581-588	8	1
β-strand	597-602	6	1
β-strand	605-611	7	1
α-helix	617-622	6
β-strand	628-632	5	1
β-strand	635-636	2	1
α-helix	642-650	9
β-strand	655-662	8	1

Chain B: 3 helices, 6 β-strands

Element	Residues	Length	Sheet
β-strand	581-588	8	2
α-helix	589-590	2
β-strand	597-602	6	2
β-strand	605-611	7	2
α-helix	617-622	6
β-strand	628-632	5	2
β-strand	635-636	2	2
α-helix	642-650	9
β-strand	655-662	8	2

Chain C: 3 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	581-589	9	3
α-helix	590	1
β-strand	597-602	6	3
β-strand	605-611	7	3
α-helix	617-622	6
β-strand	628-632	5	3
β-strand	635-636	2	3
α-helix	642-646	5
β-strand	654-662	9	3
β-strand	668	1	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Inactivation-no-after-potential D protein	A, B, C	protein	90	Drosophila melanogaster	Q24008 (AlphaFold model)

Sequence of entity 1 (A, B, C), FASTA

>2QKU_1 Inactivation-no-after-potential D protein (chains A, B, C)
LEKFNVDLMKKAGKELGLSLSPNEIGCTIADLIQGQYPEIDSKLQRGDIITKFNGDALEG
LPFQVCYALFKGANGKVSMEVTRPKPAAAS

Primary citation

Dynamic Scaffolding in a G Protein-Coupled Signaling System. Mishra, P., Socolich, M., Wall, M.A. et al. Cell (2007) 131:80-92. DOI 10.1016/j.cell.2007.07.037 · PubMed

Other PDB entries of the same protein (UniProt Q24008 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2QKV 1.55 Å, Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD
5F67 1.76 Å, An exquisitely specific PDZ/target recognition revealed by the structure of INAD PDZ3 in…
1IHJ 1.8 Å, Crystal Structure of the N-terminal PDZ domain of InaD in complex with a NorpA…
2QKT 2.05 Å, Crystal Structure of the 5th PDZ domain of InaD
3R0H 2.6 Å, Structure of INAD PDZ45 in complex with NG2 peptide
6IRE 3.25 Å, Complex structure of INAD PDZ45 and NORPA CC-PBM
2LA8 Solution structure of INAD PDZ5 complexed with Kon-tiki peptide

Browse structure collections

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