Crystal structure of the Mus81-Eme1 complex. Determined by X-ray diffraction at 2.8 Å resolution. Released 29 Apr 2008.
Explore 2ZIW in 3D Show helices and sheets RCSB PDB PDBe
2ZIW contains 23 α-helices and 21 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 320-325 | 6 | 1 |
| α-helix | 340-346 | 7 | |
| β-strand | 352-354 | 3 | 1 |
| β-strand | 363-367 | 5 | 1 |
| α-helix | 368-369 | 2 | |
| β-strand | 384-395 | 12 | 1 |
| α-helix | 396-405 | 10 | |
| α-helix | 408-415 | 8 | |
| β-strand | 422-428 | 7 | 1 |
| α-helix | 441-453 | 13 | |
| β-strand | 458-461 | 4 | 1 |
| α-helix | 465-480 | 16 | |
| β-strand | 515-516 | 2 | 1 |
| α-helix | 517-528 | 12 | |
| β-strand | 531 | 1 | 2 |
| α-helix | 532-540 | 9 | |
| β-strand | 543 | 1 | 3 |
| α-helix | 548-557 | 10 | |
| α-helix | 561-569 | 9 | |
| α-helix | 574-577 | 4 | |
| β-strand | 585 | 1 | 4 |
| β-strand | 592 | 1 | 4 |
| α-helix | 594-605 | 12 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 256 | 1 | 5 |
| α-helix | 258-261 | 4 | |
| α-helix | 266-275 | 10 | |
| β-strand | 282 | 1 | 5 |
| β-strand | 290-291 | 2 | 6 |
| β-strand | 313-315 | 3 | 6 |
| α-helix | 350-355 | 6 | |
| β-strand | 362-364 | 3 | 6 |
| β-strand | 366-367 | 2 | 7 |
| α-helix | 406-416 | 11 | |
| β-strand | 422 | 1 | 6 |
| β-strand | 425-426 | 2 | 7 |
| α-helix | 430-443 | 14 | |
| α-helix | 456-460 | 5 | |
| β-strand | 469 | 1 | 3 |
| α-helix | 478-486 | 9 | |
| α-helix | 494-503 | 10 | |
| α-helix | 507-514 | 8 | |
| α-helix | 520-523 | 4 | |
| α-helix | 548-557 | 10 | |
| β-strand | 565 | 1 | 2 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Mus81 protein | A | protein | 311 | Danio rerio | Q7SXA9 (AlphaFold model) |
| Crossover junction endonuclease EME1 | B | protein | 341 | Homo sapiens | Q96AY2 (AlphaFold model) |
>2ZIW_1 Mus81 protein (chains A) MSETGRTAMGWHLSPGSYDIVLCVDLCETTGGSSVRKQELVKELQRNSVTFDVRKLNVGD FLWVARERVTPVPGQLRPPVGKELVLDYIIERKRMDDLCGSIIDGRFREQKFRLKRCGLR KPIYLVEECGSAAAHLSIPESTLQQAIVNTQVVDGFFVKRVQDAKESAAYLTIMTRYLQK LYQNCTLFCRSRELEGDGEAESEKMVANLSCSLMAFTEFNYGAIKNKCQTVREVFARQLM QISGVSGDKAAAVLEHYSTVSSLLQAYDKCSSETEKEKLLSSVKYGKLKRNLGPALSRTI YQLYCTRGPLS
>2ZIW_2 Crossover junction endonuclease EME1 (chains B) MGSSHHHHHHSQDPNSEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPC SVTWRRRAGPSEDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTD ITAKTAGKALSLVIVDQEKCFSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVDAE EALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAGGV KVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLLAD IQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
Crystal structure of the Mus81-Eme1 complex. Chang, J.H., Kim, J.J., Choi, J.M. et al. Genes Dev (2008) 22:1093-1106. DOI 10.1101/gad.1618708 · PubMed
Other PDB entries of the same protein (UniProt Q7SXA9 (AlphaFold model), which also has an AlphaFold model), best resolution first:
MolViewer shows 2ZIW directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.