Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain. Determined by X-ray diffraction at 1.3 Å resolution. Released 21 Apr 2010.
Explore 3KZD in 3D Show helices and sheets RCSB PDB PDBe
3KZD contains 4 α-helices and 6 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 842-849 | 8 | 1 |
| β-strand | 860-865 | 6 | 1 |
| β-strand | 872-878 | 7 | 1 |
| α-helix | 883-886 | 4 | |
| β-strand | 894-898 | 5 | 1 |
| β-strand | 901-902 | 2 | 1 |
| α-helix | 903-905 | 3 | |
| α-helix | 908-916 | 9 | |
| β-strand | 919-926 | 8 | 1 |
| α-helix | 927-929 | 3 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| T-lymphoma invasion and metastasis-inducing protein 1 | A | protein | 94 | Homo sapiens | Q13009 (AlphaFold model) |
>3KZD_1 T-lymphoma invasion and metastasis-inducing protein 1 (chains A) GAMGKVTHSIHIEKSDTAADTYGFSLSSVEEDGIRRLYVNSVKETGLASKKGLKAGDEIL EINNRAADALNSSMLKDFLSQPSLGLLVRTYPEL
The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion. Shepherd, T.R., Klaus, S.M., Liu, X. et al. J Mol Biol (2010) 398:730-746. DOI 10.1016/j.jmb.2010.03.047 · PubMed
Other PDB entries of the same protein (UniProt Q13009 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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