3SGN: Alpha-crystallin B chain

Bromoderivative-8 of amyloid-related segment of alphaB-crystallin residues 90-100. Determined by X-ray diffraction at 2.81 Å resolution. Released 21 Mar 2012.

Method: X-ray diffraction
Resolution: 2.81 Å
Organism: Homo sapiens
Chains: 2
Atoms: 172
Mol. weight: 2.55 kDa
Released: 21 Mar 2012

Explore 3SGN in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3SGN contains 0 α-helices and 2 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chains A and B: 0 helices, 1 β-strand

Element	Residues	Length	Sheet
β-strand	2-10	9	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Alpha-crystallin B chain	A, B	protein	11	Homo sapiens	P02511 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>3SGN_1 Alpha-crystallin B chain (chains A, B)
KVKVLGDXIEV

Primary citation

Atomic view of a toxic amyloid small oligomer. Laganowsky, A., Liu, C., Sawaya, M.R. et al. Science (2012) 335:1228-1231. DOI 10.1126/science.1213151 · PubMed

Other PDB entries of the same protein (UniProt P02511 (AlphaFold model), which also has an AlphaFold model), best resolution first:

4M5S 1.37 Å, Human alphaB crystallin core domain in complex with C-terminal peptide
3SGP 1.4 Å, Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
7ROJ 1.6 Å, Amyloid-related segment of alphaB-crystallin residues 90-100 with G95W mutation
3SGM 1.7 Å, Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100
3SGS 1.7 Å, Amyloid-related segment of alphaB-crystallin residues 95-100
2Y1Y 2.0 Å, Human alphaB crystallin ACD(residues 71-157)
4M5T 2.0 Å, Disulfide trapped human alphaB crystallin core domain in complex with C-terminal peptide
3SGR 2.17 Å, Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
2Y1Z 2.5 Å, Human alphaB Crystallin ACD R120G
3SGO 2.56 Å, Amyloid-related segment of alphaB-crystallin residues 90-100
2WJ7 2.63 Å, human alphaB crystallin
5VVV 2.8 Å, Structural Investigations of the Substrate Specificity of Human O-GlcNAcase

Browse structure collections

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