3U1A: Smooth muscle tropomyosin alpha

N-terminal 81-aa fragment of smooth muscle tropomyosin alpha. Determined by X-ray diffraction at 2.0 Å resolution. Released 23 Nov 2011.

Method: X-ray diffraction
Resolution: 2.0 Å
Organism: Gallus gallus
Chains: 4
Atoms: 2,878
Mol. weight: 38.44 kDa
Released: 23 Nov 2011

Explore 3U1A in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3U1A contains 4 α-helices and 0 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chains A and B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	1-80	80

Chain C: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	3-80	78

Chain D: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	1-78	78

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
smooth muscle tropomyosin alpha	A, B, C, D	protein	84	Gallus gallus	P04268 (AlphaFold model)

Sequence of entity 1 (A, B, C, D), FASTA

>3U1A_1 smooth muscle tropomyosin alpha (chains A, B, C, D)
AGHMDAIKKKMQMLKLDKENALDRAEQAEADKKAAEERSKQLEDDIVQLEKQLRVTEDSR
DQVLEELHKSEDSLLFAEENAAKA

Primary citation

Structural analysis of smooth muscle tropomyosin alpha and beta isoforms. Rao, J.N., Rivera-Santiago, R., Li, X.E. et al. J Biol Chem (2012) 287:3165-3174. DOI 10.1074/jbc.M111.307330 · PubMed

Other PDB entries of the same protein (UniProt P04268 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3U1C 1.8 Å, Anti-parallel dimer of N-terminal 98-aa fragment of smooth muscle tropomyosin alpha
1IC2 2.0 Å, Deciphering the design of the tropomyosin molecule
3MTU 2.1 Å, Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle
3MUD 2.2 Å, Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle

Browse structure collections

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