Small molecular fragment bound to crystal contact interface of Interleukin-2. Determined by X-ray diffraction at 1.92 Å resolution. Released 19 Nov 2014.
Explore 4NEJ in 3D Show helices and sheets RCSB PDB PDBe
4NEJ contains 8 α-helices and 4 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 5-29 | 25 | |
| α-helix | 33-39 | 7 | |
| β-strand | 44 | 1 | 1 |
| β-strand | 47 | 1 | 2 |
| α-helix | 53-56 | 4 | |
| α-helix | 57-73 | 17 | |
| α-helix | 85-97 | 13 | |
| α-helix | 105-106 | 2 | |
| β-strand | 107 | 1 | 2 |
| α-helix | 108 | 1 | |
| β-strand | 112 | 1 | 1 |
| α-helix | 114-129 | 16 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Interleukin-2 | A | protein | 130 | Homo sapiens | P60568 (AlphaFold model) |
>4NEJ_1 Interleukin-2 (chains A) SSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEEL KPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWIT FSQSIISTLT
| ID | Name | Formula | Copies |
|---|---|---|---|
| 2K1 | 5-methylfuran-2-carboxylic acid | C6 H6 O3 | 2 |
Small molecular fragments bound to binding energy hot-spot in crystal contact interface of Interleukin-2. Brenke, R., Jehle, S., Vajda, S. et al. To be published.
Other PDB entries of the same protein (UniProt P60568 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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