4OWT: SOSS1 complex assembly

Structural basis of SOSS1 complex assembly. Determined by X-ray diffraction at 2.0 Å resolution. Released 16 Apr 2014.

Method
X-ray diffraction
Resolution
2.0 Å
Organism
Homo sapiens
Chains
3
Atoms
5,018
Mol. weight
87.95 kDa
Released
16 Apr 2014

Explore 4OWT in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4OWT contains 39 α-helices and 14 β-strands across 3 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 36 helices, 5 β-strands

ElementResiduesLengthSheet
β-strand3711
β-strand4312
α-helix44-463
α-helix47-6317
α-helix69-7911
α-helix83-9917
α-helix104-11411
α-helix120-13213
α-helix134-1363
β-strand13711
α-helix139-15416
α-helix160-16910
α-helix178-19316
α-helix195-1984
α-helix202-21615
α-helix223-24220
α-helix244-2474
α-helix248-2503
α-helix252-2609
α-helix265-27612
α-helix278-2814
α-helix288-2925
α-helix295-2973
α-helix298-3036
α-helix307-31610
α-helix3201
β-strand32113
α-helix326-33611
α-helix341-3444
α-helix345-35511
α-helix361-3655
β-strand36813
α-helix371-38010
α-helix385-39511
α-helix409-42214
α-helix427-44317
α-helix446-4483
α-helix449-46517
α-helix473-4764
α-helix483-49210
α-helix494-4963
Chain B: 2 helices, 7 β-strands
ElementResiduesLengthSheet
α-helix7-93
β-strand20-2672
β-strand40-4562
β-strand48-5362
α-helix56-616
β-strand66-6942
β-strand8412
β-strand93-9752
β-strand10712
Chain C: 1 helix, 2 β-strands
ElementResiduesLengthSheet
α-helix65-7814
β-strand83-8534
β-strand94-9634

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Integrator complex subunit 3Aprotein466Homo sapiensQ68E01 (AlphaFold model)
SOSS complex subunit B1Bprotein211Homo sapiensQ9BQ15 (AlphaFold model)
SOSS complex subunit CCprotein104Homo sapiensQ9NRY2 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>4OWT_1 Integrator complex subunit 3 (chains A)
GGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLPQHEEICLG
LFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVREL
VKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTY
LRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWK
DIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWF
QRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAK
LALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHV
RQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCS
Sequence of entity 2 (B), FASTA
>4OWT_2 SOSS complex subunit B1 (chains B)
MTTETFVKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGN
LIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYSTQQA
PNKAVQNDSNPSASQPTTGPSAASPASENQNGNGLSAPPGPGGGPHPPHTPSHPPSTRIT
RSQPNHTPAGPPGPSSNPVSNGKETRRSSKR
Sequence of entity 3 (C), FASTA
>4OWT_3 SOSS complex subunit C (chains C)
MAANSSGQGFQNKNRVAILAELDKEKRKLLMQNQSSTNHPGASIALSRPSLNKDFRDHAE
QQHIAAQQKAALQHAHAHSSGYFITQDSAFGNLILPVLPRLDPE

Primary citation

Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA. Ren, W., Chen, H., Sun, Q. et al. Cell Rep (2014) 6:982-991. DOI 10.1016/j.celrep.2014.02.020 · PubMed

Other PDB entries of the same protein (UniProt Q68E01 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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