Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain. Determined by X-ray diffraction at 3.01 Å resolution. Released 4 May 2016.
Explore 5JJW in 3D Show helices and sheets RCSB PDB PDBe
5JJW contains 27 α-helices and 10 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 281-290 | 10 | |
| α-helix | 296-304 | 9 | |
| α-helix | 306 | 1 | |
| α-helix | 310-323 | 14 | |
| α-helix | 326-340 | 15 | |
| α-helix | 344-353 | 10 | |
| α-helix | 354-358 | 5 | |
| α-helix | 361-374 | 14 | |
| α-helix | 379-391 | 13 | |
| α-helix | 396-409 | 14 | |
| α-helix | 414-430 | 17 | |
| α-helix | 440-455 | 16 | |
| α-helix | 456-460 | 5 | |
| α-helix | 461-464 | 4 | |
| α-helix | 473-486 | 14 | |
| α-helix | 489-499 | 11 | |
| α-helix | 500-504 | 5 | |
| α-helix | 508-521 | 14 | |
| α-helix | 524-537 | 14 | |
| α-helix | 542-556 | 15 | |
| α-helix | 559-573 | 15 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 9-20 | 12 | |
| β-strand | 29-34 | 6 | 1 |
| α-helix | 35-45 | 11 | |
| α-helix | 58-60 | 3 | |
| β-strand | 65 | 1 | 2 |
| β-strand | 85 | 1 | 1 |
| β-strand | 89-93 | 5 | 1 |
| α-helix | 94-104 | 11 | |
| β-strand | 106 | 1 | 2 |
| β-strand | 114-116 | 3 | 1 |
| β-strand | 117-120 | 4 | 3 |
| β-strand | 126-129 | 4 | 3 |
| β-strand | 157 | 1 | 4 |
| α-helix | 158-162 | 5 | |
| β-strand | 197 | 1 | 4 |
| α-helix | 198-201 | 4 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Squamous cell carcinoma antigen recognized by T-cells 3 | A | protein | 300 | Homo sapiens | Q15020 (AlphaFold model) |
| Ubiquitin carboxyl-terminal hydrolase 15 | B | protein | 224 | Homo sapiens | Q9Y4E8 (AlphaFold model) |
>5JJW_1 Squamous cell carcinoma antigen recognized by T-cells 3 (chains A) MSVIQNYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALV ENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQV ISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQ EVEERFNESGDPSCVIMQNWARIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLE RAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNE
>5JJW_2 Ubiquitin carboxyl-terminal hydrolase 15 (chains B) GMAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQN VYPGPIDNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVE QGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDTIEKEIRKIFSIPDEKETRL WNKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRG
Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain. Zhang, Q., Dong, A., Walker, J.R. et al. To be published.
Other PDB entries of the same protein (UniProt Q15020 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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