5LE0: MICAL1 Cterminal domain

MICAL1 Cterminal domain. Determined by X-ray diffraction at 3.3 Å resolution. Released 1 Mar 2017.

Method: X-ray diffraction
Resolution: 3.3 Å
Organism: Homo sapiens
Chains: 1
Atoms: 956
Mol. weight: 17.67 kDa
Released: 1 Mar 2017

Explore 5LE0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5LE0 contains 3 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain B: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	930-953	24
α-helix	965-1015	51
α-helix	1024-1057	34

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Protein-methionine sulfoxide oxidase MICAL1	B	protein	150	Homo sapiens	Q8TDZ2 (AlphaFold model)

Sequence of entity 1 (B), FASTA

>5LE0_1 Protein-methionine sulfoxide oxidase MICAL1 (chains B)
KEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQL
VDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKL
VDLVNQRDALIRFQEERRLSELALGTGAQG

Primary citation

Oxidation of F-actin controls the terminal steps of cytokinesis. Fremont, S., Hammich, H., Bai, J. et al. Nat Commun (2017) 8:14528-14528. DOI 10.1038/ncomms14528 · PubMed

Other PDB entries of the same protein (UniProt Q8TDZ2 (AlphaFold model), which also has an AlphaFold model), best resolution first:

8HLO 1.17 Å, Crystal structure of ASAP1-SH3 and MICAL1-PRM complex
6KU0 1.6 Å, Crystal structure of MyoVa-GTD in complex with MICAL1-GTBM
9G0C 1.8 Å, Structure of human Mical1 bMERB_V978A_V985A domain:Rab10 complex.
9G0D 2.05 Å, Structure of human Mical1 bMERB_V978A domain:Rab10 complex.
5LPN 2.8 Å, Structure of human Rab10 in complex with the bMERB domain of Mical-1
9EWY 3.1 Å, CryoEM structure of human MICAL1
8Y6K 3.94 Å, Cryo-EM structure of full-length MICAL1 in the autoinhibited state
1WYL Solution structure of the CH domain of human NEDD9 interacting protein with calponin…
2CO8 Solution structures of the LIM domain of human NEDD9 interacting protein with calponin…
2DK9 Solution structure of Calponin Homology domain of Human MICAL-1

Browse structure collections

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