7FFS: Human Serum Albumin_1

Human Serum Albumin_1. Determined by X-ray diffraction at 2.05 Å resolution. Released 27 Jul 2022.

Method: X-ray diffraction
Resolution: 2.05 Å
Organism: Homo sapiens
Chains: 1
Atoms: 4,747
Mol. weight: 66.57 kDa
Released: 27 Jul 2022

Explore 7FFS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7FFS contains 35 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 35 helices, 0 β-strands

Element	Residues	Length
α-helix	6-14	9
α-helix	16-30	15
α-helix	36-55	20
α-helix	66-74	9
α-helix	89-92	4
α-helix	95-104	10
α-helix	120-129	10
α-helix	131-145	15
α-helix	151-168	18
α-helix	174-206	33
α-helix	208-222	15
α-helix	228-246	19
α-helix	250-266	17
α-helix	268-270	3
α-helix	278-280	3
α-helix	283-291	9
α-helix	293-299	7
α-helix	302-304	3
α-helix	306-309	4
α-helix	315-321	7
α-helix	323-336	14
α-helix	343-360	18
α-helix	366-370	5
α-helix	374-376	3
α-helix	377-414	38
α-helix	420-437	18
α-helix	442-444	3
α-helix	445-465	21
α-helix	471-479	9
α-helix	484-490	7
α-helix	498-499	2
α-helix	511-514	4
α-helix	518-535	18
α-helix	541-559	19
α-helix	566-579	14

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Serum albumin	A	protein	585	Homo sapiens	P02768 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>7FFS_1 Serum albumin (chains A)
DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAE
NCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEV
DVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLP
KLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTK
VHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPA
DLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKC
CAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVST
PTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES
LVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKAT
KEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

Primary citation

Human Serum Albumin. Xiang, W., Yue, Z.L., Su, J.Y. To be published.

Other PDB entries of the same protein (UniProt P02768 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9IK6 1.69 Å, Human Serum Albumin crystallized with T4, pH 6.5
6YG9 1.89 Å, Crystal structure of human serum albumin (HSA) in complex with gn-07.
1N5U 1.9 Å, X-ray study of human serum albumin complexed with heme
8RCO 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid II at 1.9 A resolution
8RCP 1.9 Å, Structure of Human Serum Albumin in complex with Myristic Acid
8RGK 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid at 1.9 A resolution
8RGL 1.9 Å, Structure of Human Serum Albumin in complex with Aristolochic Acid I at 1.9 A resolution…
9EOD 1.9 Å, Human serum albumin with adamantene carboxylic acid
9CSG 1.91 Å, Human Serum Albumin Bound to Cerastecin Compound 5e
6QIO 1.95 Å, Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the…
9IK7 1.97 Å, Human Serum Albumin crystallized with T4, pH 7.5
7VR0 1.98 Å, Human Serum Albumin

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