7Z8J: Cytoplasmic dynein
Cytoplasmic dynein (A2) bound to BICDR1. Determined by electron microscopy at 3.93 Å resolution. Released 27 Jul 2022.
- Method
- Electron microscopy
- Resolution
- 3.93 Å
- Organisms
- Mus musculus, Homo sapiens
- Chains
- 9
- Atoms
- 20,189
- Mol. weight
- 1981.44 kDa
- Released
- 27 Jul 2022
Explore 7Z8J in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7Z8J contains 93 α-helices and 79 β-strands across 9 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain f: 32 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 271-282 | 12 | |
| α-helix | 333-336 | 4 | |
| α-helix | 341-346 | 6 | |
| α-helix | 350-364 | 15 | |
| α-helix | 365-369 | 5 | |
| α-helix | 374-399 | 26 | |
| α-helix | 406-440 | 35 | |
| α-helix | 455-483 | 29 | |
| α-helix | 514-531 | 18 | |
| α-helix | 540-574 | 35 | |
| α-helix | 578-587 | 10 | |
| α-helix | 590-592 | 3 | |
| α-helix | 598-624 | 27 | |
| α-helix | 631-638 | 8 | |
| α-helix | 643-669 | 27 | |
| α-helix | 673-675 | 3 | |
| α-helix | 677-692 | 16 | |
| α-helix | 696-709 | 14 | |
| β-strand | 716 | 1 | 1 |
| β-strand | 718-724 | 7 | 2 |
| β-strand | 731-737 | 7 | 2 |
| α-helix | 741-756 | 16 | |
| α-helix | 762-773 | 12 | |
| α-helix | 775-797 | 23 | |
| α-helix | 799-802 | 4 | |
| α-helix | 806-819 | 14 | |
| β-strand | 823 | 1 | 1 |
| α-helix | 829-863 | 35 | |
| α-helix | 864-866 | 3 | |
| α-helix | 871-891 | 21 | |
| α-helix | 896-926 | 31 | |
| α-helix | 975-994 | 20 | |
| β-strand | 997 | 1 | 3 |
| α-helix | 998-999 | 2 | |
| α-helix | 1014-1017 | 4 | |
| β-strand | 1018 | 1 | 3 |
| α-helix | 1020-1025 | 6 | |
| α-helix | 1031-1047 | 17 | |
Chain h: 7 helices, 32 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 265-271 | 7 | 4 |
| β-strand | 282-287 | 6 | 5 |
| β-strand | 294-299 | 6 | 5 |
| β-strand | 311-317 | 7 | 5 |
| β-strand | 327-331 | 5 | 5 |
| α-helix | 334 | 1 | |
| β-strand | 335-340 | 6 | 6 |
| β-strand | 347-352 | 6 | 6 |
| β-strand | 357-361 | 5 | 6 |
| β-strand | 371-372 | 2 | 6 |
| β-strand | 386-392 | 7 | 7 |
| β-strand | 395-401 | 7 | 7 |
| β-strand | 406-410 | 5 | 7 |
| β-strand | 411 | 1 | 8 |
| β-strand | 414 | 1 | 8 |
| β-strand | 420-423 | 4 | 7 |
| β-strand | 425 | 1 | 9 |
| β-strand | 431 | 1 | 9 |
| β-strand | 434-438 | 5 | 10 |
| β-strand | 446-451 | 6 | 10 |
| β-strand | 456-460 | 5 | 10 |
| β-strand | 467-472 | 6 | 10 |
| β-strand | 479-484 | 6 | 11 |
| β-strand | 496-501 | 6 | 11 |
| β-strand | 506-510 | 5 | 11 |
| β-strand | 519-520 | 2 | 11 |
| β-strand | 527-532 | 6 | 12 |
| β-strand | 539-544 | 6 | 12 |
| β-strand | 548-553 | 6 | 12 |
| β-strand | 563-566 | 4 | 12 |
| α-helix | 567 | 1 | |
| α-helix | 571-572 | 2 | |
| β-strand | 573-578 | 6 | 4 |
| β-strand | 584-589 | 6 | 4 |
| β-strand | 594-599 | 6 | 4 |
| α-helix | 600 | 1 | |
| α-helix | 601-604 | 4 | |
| α-helix | 606-607 | 2 | |
| α-helix | 610-620 | 11 | |
Chain j: 14 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 113-121 | 9 | |
| β-strand | 133-138 | 6 | 13 |
| α-helix | 142-144 | 3 | |
| α-helix | 145-163 | 19 | |
| α-helix | 167-182 | 16 | |
| β-strand | 227-232 | 6 | 13 |
| α-helix | 234-236 | 3 | |
| α-helix | 237-243 | 7 | |
| α-helix | 248-265 | 18 | |
| β-strand | 268-271 | 4 | 13 |
| β-strand | 273 | 1 | 14 |
| β-strand | 278 | 1 | 14 |
| α-helix | 280-292 | 13 | |
| β-strand | 301 | 1 | 13 |
| β-strand | 309-310 | 2 | 13 |
| α-helix | 317-326 | 10 | |
| α-helix | 336-339 | 4 | |
| α-helix | 350-352 | 3 | |
| α-helix | 356-358 | 3 | |
| α-helix | 359-372 | 14 | |
| α-helix | 427-438 | 12 | |
Chain m: 25 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 271-291 | 21 | |
| α-helix | 323-337 | 15 | |
| α-helix | 342-345 | 4 | |
| α-helix | 350-364 | 15 | |
| α-helix | 365-369 | 5 | |
| α-helix | 374-398 | 25 | |
| α-helix | 406-440 | 35 | |
| α-helix | 442-444 | 3 | |
| α-helix | 457-482 | 26 | |
| α-helix | 514-532 | 19 | |
| α-helix | 540-574 | 35 | |
| α-helix | 578-587 | 10 | |
| α-helix | 590-593 | 4 | |
| α-helix | 595-600 | 6 | |
| α-helix | 603-624 | 22 | |
| α-helix | 631-638 | 8 | |
| α-helix | 643-669 | 27 | |
| α-helix | 673-675 | 3 | |
| α-helix | 679-692 | 14 | |
| α-helix | 696-709 | 14 | |
| β-strand | 716 | 1 | 15 |
| β-strand | 718-719 | 2 | 16 |
| β-strand | 736-737 | 2 | 16 |
| α-helix | 742-756 | 15 | |
| α-helix | 762-797 | 36 | |
| α-helix | 799-802 | 4 | |
| α-helix | 806-820 | 15 | |
| β-strand | 823 | 1 | 15 |
| α-helix | 829-850 | 22 | |
Chain n: 8 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 466-480 | 15 | |
| α-helix | 518-530 | 13 | |
| α-helix | 547-574 | 28 | |
| α-helix | 578-587 | 10 | |
| α-helix | 597-615 | 19 | |
| α-helix | 662-666 | 5 | |
| α-helix | 673-675 | 3 | |
| α-helix | 677-680 | 4 | |
Chain o: 4 helices, 30 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 265-271 | 7 | 17 |
| β-strand | 282-287 | 6 | 18 |
| β-strand | 294-299 | 6 | 18 |
| β-strand | 311-317 | 7 | 18 |
| β-strand | 327-331 | 5 | 18 |
| β-strand | 338-340 | 3 | 19 |
| β-strand | 347-350 | 4 | 19 |
| β-strand | 358-361 | 4 | 19 |
| β-strand | 371-372 | 2 | 19 |
| β-strand | 384-392 | 9 | 20 |
| β-strand | 395-402 | 8 | 20 |
| β-strand | 406-410 | 5 | 20 |
| β-strand | 420-423 | 4 | 20 |
| β-strand | 425 | 1 | 21 |
| β-strand | 431 | 1 | 21 |
| β-strand | 434-438 | 5 | 22 |
| β-strand | 446-451 | 6 | 22 |
| β-strand | 456-460 | 5 | 22 |
| β-strand | 467-472 | 6 | 22 |
| β-strand | 479-484 | 6 | 23 |
| β-strand | 496-501 | 6 | 23 |
| β-strand | 505-510 | 6 | 23 |
| β-strand | 518-520 | 3 | 23 |
| β-strand | 527-532 | 6 | 24 |
| β-strand | 539-544 | 6 | 24 |
| β-strand | 548-553 | 6 | 24 |
| β-strand | 563-566 | 4 | 24 |
| β-strand | 573-578 | 6 | 17 |
| β-strand | 584-589 | 6 | 17 |
| β-strand | 594-599 | 6 | 17 |
| α-helix | 600 | 1 | |
| α-helix | 601-604 | 4 | |
| α-helix | 606-607 | 2 | |
| α-helix | 610-620 | 11 | |
Chain r: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 427-438 | 12 | |
Chains x and X: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 101-191 | 91 | |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| BICD family-like cargo adapter 1 | X, x | protein | 577 | Mus musculus | A0JNT9 (AlphaFold model) |
| Cytoplasmic dynein 1 heavy chain 1 | f, m, n | protein | 4646 | Homo sapiens | Q14204 |
| Cytoplasmic dynein 1 intermediate chain 2 | h, o | protein | 638 | Homo sapiens | Q13409 (AlphaFold model) |
| Cytoplasmic dynein 1 light intermediate chain 2 | j, r | protein | 492 | Homo sapiens | O43237 (AlphaFold model) |
Sequence of entity 1 (X, x), FASTA
>7Z8J_1 BICD family-like cargo adapter 1 (chains X, x)
MSAFCLGLAGRASAPAEPDSACCMELPAGAGDAVRSPATAAALVSFPGGPGELELALEEE
LALLAAGERSSEPGEHPQAEPESPVEGHGPPLPPPPTQDPELLSVIRQKEKDLVLAARLG
KALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELETDVKQL
QDELERQQLHLREADREKTRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALKEDFREK
NSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQG
HDKDLQLHQSQLELQEVRLSYRQLQGKVEELTEERSLQSSAATSTSLLSEIEQSMEAEEL
EQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRT
ALNDLKRLIQSIVDGVEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEA
IAKKNAVELELAKCKMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLK
EQSRPAAAAFPRGHGVGRGQEPSTADGKRLFSFFRKI
Sequence of entity 2 (f, m, n), FASTA
>7Z8J_2 Cytoplasmic dynein 1 heavy chain 1 (chains f, m, n)
MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS
ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK
RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP
SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT
FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT
LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI
FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF
QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI
VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK
EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA
IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA
YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI
ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS
LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV
FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV
NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH
ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR
NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ
ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT
EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ
RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD
WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ
VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY
ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ
KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH
INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL
LPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLE
RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE
GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT
WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ
PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ
MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG
HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE
ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA
MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA
GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL
LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL
MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF
THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR
IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG
KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS
MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR
ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL
LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE
YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW
VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP
SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG
LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD
YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG
AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL
DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR
NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY
IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI
NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL
KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK
KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS
DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE
DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK
SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN
IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI
MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV
LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE
RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV
TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL
YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT
YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW
LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI
MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA
DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR
AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG
WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF
DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW
LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL
HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG
KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG
AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV
TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF
TVDFEIATKEDPRSFYERGVAVLCTE
Sequence of entity 3 (h, o), FASTA
>7Z8J_3 Cytoplasmic dynein 1 intermediate chain 2 (chains h, o)
MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA
EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDP
SVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVA
PKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ
INIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN
NNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW
DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQD
SMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT
GIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALF
ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVG
EQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
Sequence of entity 4 (j, r), FASTA
>7Z8J_4 Cytoplasmic dynein 1 light intermediate chain 2 (chains j, r)
MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVF
GEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLK
FAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVL
EKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPA
LVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIK
NNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPD
SMVTNSSTENEA
Primary citation
Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Chaaban, S., Carter, A.P. Nature (2022) 610:212-216. DOI 10.1038/s41586-022-05186-y · PubMed
Other PDB entries of the same protein (UniProt A0JNT9 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7Z8I 3.3 Å, The barbed end complex of dynactin bound to BICDR1 and the cytoplasmic dynein tails (A2,…
- 7Z8M 3.37 Å, The pointed end complex of dynactin bound to BICDR1
- 6F1U 3.4 Å, N terminal region of dynein tail domains in complex with dynactin filament and BICDR-1
- 6F1T 3.5 Å, Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1
- 6ZNM 4.1 Å, The pointed end complex of dynactin bound to BICDR1
- 7Z8K 4.37 Å, Cytoplasmic dynein (A1) bound to BICDR1
- 9DGU 7.1 Å, structure of dynactin, dynein tail with two BICDR from dynein-dynactin-BICDR on…
- 9DGT 7.2 Å, structure of dynactin, dynein tail with one BICDR from dynein-dynactin-BICDR on…
- 7Z8F 20.0 Å, Composite structure of dynein-dynactin-BICDR on microtubules
Browse structure collections
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