9QVN: Gamma-tubulin complex component 3
Cryo-EM reconstruction of the NEDD1 anchor protein bound to the gamma-tubulin ring complex. Determined by electron microscopy at 4.7 Å resolution. Released 21 May 2025.
- Method
- Electron microscopy
- Resolution
- 4.7 Å
- Organism
- Homo sapiens
- Chains
- 45
- Atoms
- 87,756
- Mol. weight
- 3154.19 kDa
- Released
- 21 May 2025
Explore 9QVN in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9QVN contains 1,014 α-helices and 366 β-strands across 45 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 25 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4-9 | 6 | 42 |
| α-helix | 11-29 | 19 | |
| β-strand | 31 | 1 | 43 |
| α-helix | 36 | 1 | |
| β-strand | 37 | 1 | 43 |
| α-helix | 38 | 1 | |
| α-helix | 48-51 | 4 | |
| β-strand | 52-54 | 3 | 44 |
| β-strand | 60-62 | 3 | 44 |
| β-strand | 64-66 | 3 | 42 |
| β-strand | 67-68 | 2 | 45 |
| α-helix | 71-78 | 8 | |
| α-helix | 81-84 | 4 | |
| α-helix | 88-90 | 3 | |
| β-strand | 92-93 | 2 | 45 |
| α-helix | 104-113 | 10 | |
| α-helix | 115-127 | 13 | |
| β-strand | 132-140 | 9 | 42 |
| α-helix | 145-160 | 16 | |
| β-strand | 165-172 | 8 | 42 |
| α-helix | 173-174 | 2 | |
| α-helix | 184-197 | 14 | |
| β-strand | 203-206 | 4 | 42 |
| α-helix | 207-216 | 10 | |
| α-helix | 225-244 | 20 | |
| α-helix | 253-258 | 6 | |
| β-strand | 269-273 | 5 | 46 |
| α-helix | 279-283 | 5 | |
| α-helix | 290-297 | 8 | |
| α-helix | 300-302 | 3 | |
| β-strand | 303 | 1 | 46 |
| β-strand | 317-325 | 9 | 46 |
| α-helix | 330-342 | 13 | |
| β-strand | 348 | 1 | 46 |
| β-strand | 356-361 | 6 | 46 |
| α-helix | 362-364 | 3 | |
| β-strand | 374-381 | 8 | 46 |
| α-helix | 384-401 | 18 | |
| α-helix | 405-409 | 5 | |
| α-helix | 412-414 | 3 | |
| α-helix | 419-437 | 19 | |
| α-helix | 441-445 | 5 | |
Chain A: 38 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 149-167 | 19 | |
| α-helix | 173-175 | 3 | |
| α-helix | 238-253 | 16 | |
| β-strand | 261-264 | 4 | 72 |
| α-helix | 265-266 | 2 | |
| α-helix | 271-272 | 2 | |
| β-strand | 273-276 | 4 | 72 |
| α-helix | 282-308 | 27 | |
| α-helix | 311-313 | 3 | |
| α-helix | 314-343 | 30 | |
| α-helix | 349-376 | 28 | |
| α-helix | 381-393 | 13 | |
| α-helix | 398-425 | 28 | |
| β-strand | 437-438 | 2 | 73 |
| α-helix | 444-449 | 6 | |
| α-helix | 454-458 | 5 | |
| β-strand | 461-462 | 2 | 73 |
| α-helix | 464-466 | 3 | |
| α-helix | 472-490 | 19 | |
| α-helix | 511-529 | 19 | |
| α-helix | 530-534 | 5 | |
| α-helix | 537-547 | 11 | |
| α-helix | 553-567 | 15 | |
| α-helix | 576-589 | 14 | |
| α-helix | 591-594 | 4 | |
| α-helix | 598-600 | 3 | |
| β-strand | 601-605 | 5 | 74 |
| α-helix | 610-620 | 11 | |
| α-helix | 625-629 | 5 | |
| α-helix | 632-634 | 3 | |
| α-helix | 640-643 | 4 | |
| β-strand | 644-648 | 5 | 74 |
| α-helix | 654-656 | 3 | |
| α-helix | 660-690 | 31 | |
| α-helix | 691-695 | 5 | |
| α-helix | 699-701 | 3 | |
| α-helix | 704-723 | 20 | |
| α-helix | 724-730 | 7 | |
| α-helix | 731-743 | 13 | |
| α-helix | 747-764 | 18 | |
| α-helix | 770-799 | 30 | |
| α-helix | 839-874 | 36 | |
| α-helix | 878-887 | 10 | |
| α-helix | 892-898 | 7 | |
Chain b: 26 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5-10 | 6 | 50 |
| α-helix | 11-29 | 19 | |
| β-strand | 31 | 1 | 51 |
| β-strand | 36 | 1 | 52 |
| β-strand | 37 | 1 | 51 |
| α-helix | 38 | 1 | |
| α-helix | 48-51 | 4 | |
| β-strand | 52-54 | 3 | 53 |
| β-strand | 59 | 1 | 52 |
| β-strand | 60-62 | 3 | 53 |
| β-strand | 64-68 | 5 | 50 |
| α-helix | 71-78 | 8 | |
| α-helix | 81-84 | 4 | |
| α-helix | 88-90 | 3 | |
| β-strand | 91-93 | 3 | 50 |
| α-helix | 104-113 | 10 | |
| α-helix | 115-127 | 13 | |
| β-strand | 134-140 | 7 | 50 |
| α-helix | 145-149 | 5 | |
| α-helix | 150-160 | 11 | |
| β-strand | 165-172 | 8 | 50 |
| α-helix | 173-174 | 2 | |
| α-helix | 184-198 | 15 | |
| β-strand | 201-206 | 6 | 50 |
| α-helix | 207-216 | 10 | |
| α-helix | 225-244 | 20 | |
| α-helix | 253-258 | 6 | |
| β-strand | 268-269 | 2 | 50 |
| β-strand | 270-274 | 5 | 54 |
| α-helix | 279-283 | 5 | |
| α-helix | 290-297 | 8 | |
| α-helix | 300-302 | 3 | |
| β-strand | 303 | 1 | 54 |
| β-strand | 317-326 | 10 | 54 |
| α-helix | 330-342 | 13 | |
| β-strand | 356-361 | 6 | 54 |
| α-helix | 362-364 | 3 | |
| α-helix | 368-369 | 2 | |
| β-strand | 373-381 | 9 | 54 |
| α-helix | 384-401 | 18 | |
| α-helix | 405-409 | 5 | |
| α-helix | 412-415 | 4 | |
| α-helix | 419-437 | 19 | |
| α-helix | 441-445 | 5 | |
Chain B: 38 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-14 | 12 | |
| β-strand | 22-25 | 4 | 13 |
| β-strand | 30-33 | 4 | 13 |
| α-helix | 41-68 | 28 | |
| α-helix | 71-73 | 3 | |
| α-helix | 74-108 | 35 | |
| α-helix | 120-144 | 25 | |
| α-helix | 149-159 | 11 | |
| α-helix | 165-192 | 28 | |
| β-strand | 204-206 | 3 | 14 |
| α-helix | 212-214 | 3 | |
| α-helix | 215-219 | 5 | |
| β-strand | 220-222 | 3 | 14 |
| α-helix | 224-226 | 3 | |
| α-helix | 233-247 | 15 | |
| α-helix | 248-252 | 5 | |
| α-helix | 274-280 | 7 | |
| α-helix | 282-285 | 4 | |
| α-helix | 287-304 | 18 | |
| α-helix | 305-309 | 5 | |
| α-helix | 311-317 | 7 | |
| α-helix | 318-322 | 5 | |
| α-helix | 327-341 | 15 | |
| β-strand | 344 | 1 | 15 |
| α-helix | 345-347 | 3 | |
| α-helix | 350-363 | 14 | |
| α-helix | 365-368 | 4 | |
| α-helix | 371-374 | 4 | |
| β-strand | 377-381 | 5 | 16 |
| α-helix | 382-384 | 3 | |
| β-strand | 389 | 1 | 15 |
| α-helix | 390-393 | 4 | |
| β-strand | 394-398 | 5 | 16 |
| α-helix | 402-406 | 5 | |
| α-helix | 410-446 | 37 | |
| α-helix | 447-449 | 3 | |
| α-helix | 451-453 | 3 | |
| α-helix | 454-476 | 23 | |
| α-helix | 477-484 | 8 | |
| α-helix | 485-496 | 12 | |
| α-helix | 500-517 | 18 | |
| α-helix | 525-571 | 47 | |
| α-helix | 579-623 | 45 | |
| α-helix | 627-636 | 10 | |
| α-helix | 641-645 | 5 | |
| α-helix | 647-655 | 9 | |
Chain c: 26 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5-10 | 6 | 58 |
| α-helix | 11-29 | 19 | |
| β-strand | 31 | 1 | 59 |
| β-strand | 36 | 1 | 60 |
| β-strand | 37 | 1 | 59 |
| α-helix | 38 | 1 | |
| α-helix | 48-50 | 3 | |
| β-strand | 52-54 | 3 | 61 |
| β-strand | 59 | 1 | 60 |
| β-strand | 60-62 | 3 | 61 |
| β-strand | 64-67 | 4 | 58 |
| α-helix | 71-78 | 8 | |
| α-helix | 81-84 | 4 | |
| α-helix | 88-90 | 3 | |
| α-helix | 104-113 | 10 | |
| α-helix | 115-127 | 13 | |
| β-strand | 134-140 | 7 | 58 |
| α-helix | 145-149 | 5 | |
| α-helix | 150-160 | 11 | |
| β-strand | 165-172 | 8 | 58 |
| α-helix | 173-174 | 2 | |
| α-helix | 184-197 | 14 | |
| β-strand | 201-206 | 6 | 58 |
| α-helix | 207-216 | 10 | |
| α-helix | 225-244 | 20 | |
| α-helix | 253-258 | 6 | |
| β-strand | 268-269 | 2 | 58 |
| β-strand | 270-274 | 5 | 62 |
| α-helix | 279-282 | 4 | |
| α-helix | 290-297 | 8 | |
| α-helix | 300-302 | 3 | |
| β-strand | 317-326 | 10 | 62 |
| α-helix | 330-342 | 13 | |
| β-strand | 356-361 | 6 | 62 |
| α-helix | 362-364 | 3 | |
| α-helix | 368-369 | 2 | |
| β-strand | 373-381 | 9 | 62 |
| α-helix | 384-401 | 18 | |
| α-helix | 405-409 | 5 | |
| α-helix | 412-415 | 4 | |
| α-helix | 419-437 | 19 | |
| α-helix | 441-445 | 5 | |
Chain C: 38 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 149-167 | 19 | |
| α-helix | 238-253 | 16 | |
| β-strand | 261-264 | 4 | 55 |
| α-helix | 265-266 | 2 | |
| α-helix | 271-272 | 2 | |
| β-strand | 273-276 | 4 | 55 |
| α-helix | 282-308 | 27 | |
| α-helix | 311-313 | 3 | |
| α-helix | 314-343 | 30 | |
| α-helix | 349-376 | 28 | |
| α-helix | 381-393 | 13 | |
| α-helix | 398-425 | 28 | |
| β-strand | 437-439 | 3 | 56 |
| α-helix | 444-449 | 6 | |
| α-helix | 454-458 | 5 | |
| β-strand | 460-462 | 3 | 56 |
| α-helix | 464-466 | 3 | |
| α-helix | 472-474 | 3 | |
| α-helix | 475-490 | 16 | |
| α-helix | 511-529 | 19 | |
| α-helix | 530-534 | 5 | |
| α-helix | 537-547 | 11 | |
| α-helix | 553-567 | 15 | |
| α-helix | 571-573 | 3 | |
| α-helix | 576-589 | 14 | |
| α-helix | 591-594 | 4 | |
| α-helix | 598-600 | 3 | |
| β-strand | 601-605 | 5 | 57 |
| α-helix | 610-620 | 11 | |
| α-helix | 625-629 | 5 | |
| α-helix | 632-634 | 3 | |
| α-helix | 640-643 | 4 | |
| β-strand | 644-648 | 5 | 57 |
| α-helix | 654-656 | 3 | |
| α-helix | 660-691 | 32 | |
| α-helix | 692-695 | 4 | |
| α-helix | 698-723 | 26 | |
| α-helix | 724-730 | 7 | |
| α-helix | 731-743 | 13 | |
| α-helix | 747-764 | 18 | |
| α-helix | 770-799 | 30 | |
| α-helix | 839-875 | 37 | |
| α-helix | 878-887 | 10 | |
| α-helix | 894-898 | 5 | |
Chain d: 24 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5-10 | 6 | 23 |
| α-helix | 11-29 | 19 | |
| β-strand | 31 | 1 | 24 |
| β-strand | 36 | 1 | 25 |
| β-strand | 37 | 1 | 24 |
| α-helix | 38 | 1 | |
| α-helix | 48-51 | 4 | |
| β-strand | 52-54 | 3 | 26 |
| β-strand | 59 | 1 | 25 |
| β-strand | 60-62 | 3 | 26 |
| β-strand | 64-67 | 4 | 23 |
| α-helix | 71-78 | 8 | |
| α-helix | 81-84 | 4 | |
| α-helix | 88-90 | 3 | |
| α-helix | 104-113 | 10 | |
| α-helix | 115-128 | 14 | |
| β-strand | 134-140 | 7 | 23 |
| α-helix | 145-160 | 16 | |
| β-strand | 165-171 | 7 | 23 |
| α-helix | 172-174 | 3 | |
| α-helix | 184-197 | 14 | |
| β-strand | 201-204 | 4 | 23 |
| α-helix | 207-218 | 12 | |
| α-helix | 225-244 | 20 | |
| α-helix | 253-258 | 6 | |
| β-strand | 270-274 | 5 | 27 |
| α-helix | 279-282 | 4 | |
| α-helix | 290-297 | 8 | |
| α-helix | 300-302 | 3 | |
| β-strand | 303 | 1 | 27 |
| β-strand | 317-326 | 10 | 27 |
| α-helix | 330-343 | 14 | |
| β-strand | 356-361 | 6 | 27 |
| α-helix | 362-364 | 3 | |
| β-strand | 373-381 | 9 | 27 |
| α-helix | 383-399 | 17 | |
| α-helix | 406-409 | 4 | |
| α-helix | 412-415 | 4 | |
| α-helix | 419-437 | 19 | |
| α-helix | 441-444 | 4 | |
Chain D: 39 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-14 | 12 | |
| β-strand | 22-25 | 4 | 1 |
| β-strand | 30-33 | 4 | 1 |
| α-helix | 41-68 | 28 | |
| α-helix | 71-73 | 3 | |
| α-helix | 74-108 | 35 | |
| α-helix | 120-144 | 25 | |
| α-helix | 149-160 | 12 | |
| α-helix | 165-192 | 28 | |
| β-strand | 204-206 | 3 | 2 |
| α-helix | 212-214 | 3 | |
| α-helix | 215-219 | 5 | |
| β-strand | 220-222 | 3 | 2 |
| α-helix | 224-226 | 3 | |
| α-helix | 233-247 | 15 | |
| α-helix | 248-252 | 5 | |
| α-helix | 260-269 | 10 | |
| α-helix | 272-280 | 9 | |
| α-helix | 282-285 | 4 | |
| α-helix | 287-304 | 18 | |
| α-helix | 305-309 | 5 | |
| α-helix | 311-317 | 7 | |
| α-helix | 318-322 | 5 | |
| α-helix | 327-341 | 15 | |
| β-strand | 344 | 1 | 3 |
| α-helix | 345-347 | 3 | |
| α-helix | 350-362 | 13 | |
| α-helix | 365-368 | 4 | |
| α-helix | 371-374 | 4 | |
| β-strand | 377-381 | 5 | 4 |
| α-helix | 382-384 | 3 | |
| β-strand | 389 | 1 | 3 |
| α-helix | 390-393 | 4 | |
| β-strand | 394-398 | 5 | 4 |
| α-helix | 404-407 | 4 | |
| α-helix | 410-446 | 37 | |
| α-helix | 447-449 | 3 | |
| α-helix | 451-453 | 3 | |
| α-helix | 454-476 | 23 | |
| α-helix | 477-484 | 8 | |
| α-helix | 485-496 | 12 | |
| α-helix | 500-517 | 18 | |
| α-helix | 525-571 | 47 | |
| α-helix | 579-623 | 45 | |
| α-helix | 627-636 | 10 | |
| α-helix | 641-645 | 5 | |
| α-helix | 647-656 | 10 | |
35 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Gamma-tubulin complex component 3 | B, D, F, H, N, r, s, t, u, v | protein | 907 | Homo sapiens | Q96CW5 (AlphaFold model) |
| Mitotic-spindle organizing protein 1 | O, P, Q, R, S, T, U | protein | 82 | Homo sapiens | Q08AG7 (AlphaFold model) |
| Protein NEDD1 | V, W, X, Y | protein | 660 | Homo sapiens | Q8NHV4 (AlphaFold model) |
| Actin, cytoplasmic 1, N-terminally processed | Z | protein | 375 | Homo sapiens | P60709 (AlphaFold model) |
| Tubulin gamma-1 chain | a, b, c, d, e, f, g, h, i, j, k, l, m, n | protein | 457 | Homo sapiens | P23258 |
| Gamma-tubulin complex component 4 | I, K | protein | 667 | Homo sapiens | Q9UGJ1 |
| Isoform 3 of Gamma-tubulin complex component 2 | A, C, E, G, M | protein | 930 | Homo sapiens | Q9BSJ2 |
| TUBGCP6 protein | L | protein | 1811 | Homo sapiens | Q96RT7 |
| Gamma-tubulin complex component 5 | J | protein | 1024 | Homo sapiens | Q96RT8 |
Sequence of entity 1 (B, D, F, H, N, r, s, t, u, v), FASTA
>9QVN_1 Gamma-tubulin complex component 3 (chains B, D, F, H, N, r, s, t, u, v)
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKK
ELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQ
ALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSL
LPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTG
GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWL
HNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLES
SLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILS
LVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQS
RKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFE
TSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI
LETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHY
LRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQY
YITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFD
QIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESI
PKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTR
GRRSSHT
Sequence of entity 2 (O, P, Q, R, S, T, U), FASTA
>9QVN_2 Mitotic-spindle organizing protein 1 (chains O, P, Q, R, S, T, U)
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEAL
SSVIKELRKATEALKAAENMTS
Sequence of entity 3 (V, W, X, Y), FASTA
>9QVN_3 Protein NEDD1 (chains V, W, X, Y)
MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV
VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD
QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS
VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK
LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ
YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA
MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN
KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT
AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI
CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL
DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF
Sequence of entity 4 (Z), FASTA
>9QVN_4 Actin, cytoplasmic 1, N-terminally processed (chains Z)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF
Sequence of entity 5 (a, b, c, d, e, f, g, h, i, j, k, l, m, n), FASTA
>9QVN_5 Tubulin gamma-1 chain (chains a, b, c, d, e, f, g, h, i, j, k, l, m, n)
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE
MDTSREIVQQLIDEYHAATRPDYISWGTQEQENLYFQ
Sequence of entity 6 (I, K), FASTA
>9QVN_6 Gamma-tubulin complex component 4 (chains I, K)
MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIE
QYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSIS
HVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCH
GVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQD
LRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSIL
KNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDF
YLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEY
HGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFK
YLLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQ
FSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQN
LGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGG
TLGSFGM
Sequence of entity 7 (A, C, E, G, M), FASTA
>9QVN_7 Isoform 3 of Gamma-tubulin complex component 2 (chains A, C, E, G, M)
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
VYERPALIGDFLIGAGISTDTALPIVLLRWNLALSPRLKCSGVISAHCNLHLPGTLPLAS
QESAVVEDLLYVLVGVDGRYVSAQPLAGRQSRTFLVDPNLDLSIRELVHRILPVAASYSA
VTRFIEEKSSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFYIQPAM
RTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPYFEVLE
KWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYWDQRYTIVQQQIPSFLQKMADKILS
TGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAH
LRSIKRYFLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDD
LKIDLMPHDLITQLLRVLAIETKQEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINR
KALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQN
IQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLTNPELLKVFSKLM
SVCVMFTNCMQKFTQSMKLDGELGGQTLEHSTVLGLPAGAEERARKELARKHLAEHADTV
QLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERL
SAERSQKATPQVPVLRGPPAPAPRVAVTAQ
Sequence of entity 8 (L), FASTA
>9QVN_8 TUBGCP6 protein (chains L)
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPD
MSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGS
GPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQ
VMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNAD
LSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERV
GCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVL
IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLD
SLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVG
AVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWV
YSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGK
TINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEE
KELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERR
QAARQEELDDDFSYARELRDRERRLKSLEEELERKASKLSAEAARREQKALWRIQRHRLE
SARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGGQGCDSGSA
EQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFLPVGPGAEP
SVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPAVATSPAPG
PLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQPTERLFGQ
VSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTHGHVSNASI
SLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNASIRVGENV
SDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGESVSDMAPT
RPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNT
HVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSAVLDCGPRLPVEVGPS
LSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDLSPNWPLNS
QEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLR
PVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFF
VELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQC
SLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGCLSKYSGVF
SFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQI
LHVTWCEFRARLATVGDLEEIQRAHAEYLHEAVFRGLLTEKAAPVMNVIHSIFSLVLKFR
SQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQPHLEDFLL
RINFNNYYQDA
Sequence of entity 9 (J), FASTA
>9QVN_9 Gamma-tubulin complex component 5 (chains J)
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHK
IEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDS
PSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSRE
DSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHS
NLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNI
IVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRT
YQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGV
AEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWI
VHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQG
PSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESV
QSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDF
HEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYL
QAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSIS
FENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDV
LLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNY
IMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAG
MEQS
Primary citation
Structure of the microtubule-anchoring factor NEDD1 bound to the gamma-tubulin ring complex. Munoz-Hernandez, H., Xu, Y., Pellicer Camardiel, A. et al. J Cell Biol (2025) 224. DOI 10.1083/jcb.202410206 · PubMed
Other PDB entries of the same protein (UniProt Q96CW5 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8RX1 3.57 Å, CryoEM structure of the gTuRC-CM1dim complex
- 6X0U 3.6 Å, Structure of MZT1/GCP3-NHD and MZT1/GCP6-NHD in the gamma-TuRC lumenal bridge
- 9SMX 3.67 Å, CM1-activated gTuRC in complex with nascent alpha-E254D mutant microtubules
- 8Q62 3.72 Å, Early closed conformation of the g-tubulin ring complex
- 6V6B 3.8 Å, Structures of GCP2 and GCP3 in the native human gamma-tubulin ring complex
- 7AS4 4.13 Å, Recombinant human gTuRC
- 6V6S 4.3 Å, Structure of the native human gamma-tubulin ring complex
- 7QJ0 5.32 Å, Structure of recombinant human gamma-Tubulin Ring Complex 6-spoked assembly intermediate…
- 9QVM 6.8 Å, Cryo-EM reconstruction of the NEDD1 anchor protein and CDK5RAP2 bound to the…
- 7QJ1 7.0 Å, Structure of the recombinant human gamma-Tubulin Ring Complex 6-spoked assembly…
- 8VRD 7.0 Å, Rigid body fitted model for free recombinant gamma tubulin ring complex.
- 7QJD 7.1 Å, Structure of recombinant human gamma-Tubulin Ring Complex without actin
Browse structure collections
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