8Q62: Tubulin gamma-1 chain

Early closed conformation of the g-tubulin ring complex. Determined by electron microscopy at 3.72 Å resolution. Released 7 Feb 2024.

Method: Electron microscopy
Resolution: 3.72 Å
Organism: Homo sapiens
Chains: 28
Atoms: 115,764
Mol. weight: 2220.64 kDa
Released: 7 Feb 2024

Explore 8Q62 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8Q62 contains 663 α-helices and 355 β-strands across 28 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain a: 19 helices, 20 β-strands

Element	Residues	Length	Sheet
β-strand	4-10	7	60
α-helix	12-28	17
β-strand	31	1	61
β-strand	36	1	62
β-strand	37	1	61
α-helix	38	1
β-strand	52-54	3	63
α-helix	55	1
β-strand	59	1	62
β-strand	60-62	3	63
β-strand	64-67	4	60
α-helix	73-78	6
α-helix	81-83	3
α-helix	104-113	10
α-helix	115-128	14
β-strand	132-137	6	60
β-strand	140	1	64
α-helix	146-160	15
β-strand	165-168	4	60
β-strand	171-172	2	64
α-helix	184-198	15
β-strand	201-203	3	60
β-strand	205-206	2	64
α-helix	207-217	11
α-helix	224-244	21
α-helix	253-260	8
β-strand	268-269	2	60
β-strand	270-273	4	65
α-helix	290-296	7
β-strand	303	1	65
β-strand	317-325	9	65
α-helix	331-343	13
α-helix	354-356	3
β-strand	358-361	4	65
α-helix	362-364	3
β-strand	374-381	8	65
α-helix	384-401	18
α-helix	409-414	6
α-helix	419-439	21

Chain A: 31 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	152-167	16
α-helix	172-175	4
α-helix	180-183	4
α-helix	210-225	16
β-strand	233-235	3	57
α-helix	236-237	2
β-strand	246-248	3	57
α-helix	254-280	27
α-helix	283-285	3
α-helix	287-316	30
α-helix	321-347	27
α-helix	353-361	9
α-helix	372-394	23
β-strand	409-411	3	58
β-strand	432-434	3	58
α-helix	444-454	11
α-helix	473-475	3
α-helix	483-497	15
α-helix	498-502	5
α-helix	503-505	3
α-helix	512-518	7
α-helix	526-540	15
α-helix	548-561	14
α-helix	563-566	4
α-helix	568-570	3
β-strand	573-577	5	59
β-strand	616-620	5	59
α-helix	625-627	3
α-helix	632-662	31
α-helix	678-696	19
α-helix	697-702	6
α-helix	703-712	10
α-helix	719-735	17
α-helix	738-740	3
α-helix	746-763	18
α-helix	815-842	28
α-helix	852-859	8

Chain b: 18 helices, 19 β-strands

Element	Residues	Length	Sheet
β-strand	4-10	7	66
α-helix	12-28	17
β-strand	31	1	67
α-helix	36	1
β-strand	37	1	67
α-helix	38	1
β-strand	52-54	3	68
β-strand	60-62	3	68
β-strand	64-67	4	66
α-helix	73-78	6
α-helix	81-83	3
β-strand	92	1	66
α-helix	104-128	25
β-strand	132-137	6	66
β-strand	140	1	69
α-helix	146-160	15
β-strand	165-168	4	66
β-strand	171-172	2	69
α-helix	184-198	15
β-strand	201-203	3	66
β-strand	205-206	2	69
α-helix	207-217	11
α-helix	224-244	21
α-helix	253-260	8
β-strand	268-269	2	66
β-strand	270-273	4	70
α-helix	290-298	9
β-strand	303	1	70
β-strand	317-325	9	70
α-helix	331-343	13
α-helix	354-356	3
β-strand	358-361	4	70
α-helix	362-364	3
β-strand	374-381	8	70
α-helix	384-401	18
α-helix	409-414	6
α-helix	420-439	20

Chain B: 29 helices, 8 β-strands

Element	Residues	Length	Sheet
α-helix	247-258	12
β-strand	266-267	2	24
β-strand	276-277	2	24
α-helix	288-313	26
α-helix	321-346	26
α-helix	368-388	21
α-helix	395-402	8
α-helix	403-406	4
α-helix	409-412	4
α-helix	415-433	19
β-strand	449-450	2	25
α-helix	459-463	5
β-strand	464-465	2	25
α-helix	468-470	3
α-helix	477-495	19
α-helix	529-537	9
α-helix	538-544	7
α-helix	545-551	7
α-helix	555-565	11
α-helix	572-580	9
α-helix	582-586	5
β-strand	588	1	26
α-helix	594-607	14
α-helix	609-611	3
α-helix	615-620	6
β-strand	623-624	2	27
β-strand	633	1	26
β-strand	639-640	2	27
α-helix	654-687	34
α-helix	698-721	24
α-helix	722-727	6
α-helix	728-740	13
α-helix	750-761	12
α-helix	766-768	3
α-helix	769-814	46
α-helix	826-863	38
α-helix	871-880	10

Chain c: 18 helices, 18 β-strands

Element	Residues	Length	Sheet
β-strand	4-10	7	71
α-helix	12-28	17
β-strand	31	1	72
α-helix	36	1
β-strand	37	1	72
α-helix	38	1
β-strand	52-54	3	73
β-strand	60-62	3	73
β-strand	64-67	4	71
α-helix	73-78	6
α-helix	81-83	3
α-helix	104-113	10
α-helix	115-128	14
β-strand	132-137	6	71
β-strand	140	1	74
α-helix	146-160	15
β-strand	165-168	4	71
β-strand	171-172	2	74
α-helix	184-198	15
β-strand	201-203	3	71
β-strand	205-206	2	74
α-helix	207-217	11
α-helix	224-244	21
α-helix	253-260	8
β-strand	268-269	2	71
β-strand	270-273	4	75
α-helix	290-297	8
β-strand	303	1	75
β-strand	317-325	9	75
α-helix	331-343	13
β-strand	357-361	5	75
α-helix	362-364	3
β-strand	374-381	8	75
α-helix	384-401	18
α-helix	409-414	6
α-helix	419-439	21

Chain C: 38 helices, 8 β-strands

Element	Residues	Length	Sheet
α-helix	151-167	17
α-helix	180-183	4
α-helix	210-224	15
β-strand	234-235	2	28
β-strand	246-247	2	28
α-helix	248-249	2
α-helix	254-263	10
α-helix	265-274	10
α-helix	289-294	6
α-helix	297-315	19
α-helix	321-327	7
α-helix	329-334	6
α-helix	336-345	10
α-helix	353-365	13
α-helix	373-382	10
α-helix	385-395	11
β-strand	409-411	3	29
α-helix	428-431	4
β-strand	432-434	3	29
α-helix	441-443	3
α-helix	447-463	17
α-helix	487-491	5
α-helix	492-499	8
α-helix	501-505	5
α-helix	509-517	9
α-helix	526-539	14
β-strand	542	1	30
α-helix	548-561	14
α-helix	563-565	3
α-helix	568-572	5
β-strand	573-576	4	31
β-strand	611	1	30
α-helix	612-614	3
β-strand	617-620	4	31
α-helix	624-627	4
α-helix	632-662	31
α-helix	678-696	19
α-helix	697-702	6
α-helix	703-712	10
α-helix	713-715	3
α-helix	719-736	18
α-helix	746-756	11
α-helix	757-762	6
α-helix	764-767	4
α-helix	817-842	26
α-helix	854-859	6

Chain d: 17 helices, 20 β-strands

Element	Residues	Length	Sheet
β-strand	4-10	7	76
α-helix	12-28	17
β-strand	31	1	77
β-strand	36	1	78
β-strand	37	1	77
α-helix	38	1
β-strand	52-54	3	79
β-strand	59	1	78
β-strand	60-62	3	79
β-strand	64-67	4	76
α-helix	73-78	6
α-helix	81-83	3
α-helix	104-113	10
α-helix	115-128	14
β-strand	132-137	6	76
β-strand	140	1	80
α-helix	146-160	15
β-strand	165-168	4	76
β-strand	171-172	2	80
α-helix	184-198	15
β-strand	201-203	3	76
β-strand	205-206	2	80
α-helix	207-217	11
α-helix	224-244	21
α-helix	253-260	8
β-strand	268-269	2	76
β-strand	270-273	4	81
α-helix	290-298	9
β-strand	303	1	81
β-strand	317-325	9	81
α-helix	331-343	13
β-strand	359-361	3	81
α-helix	362-364	3
β-strand	374-381	8	81
α-helix	384-401	18
α-helix	409-414	6
α-helix	419-439	21

Chain D: 30 helices, 8 β-strands

Element	Residues	Length	Sheet
α-helix	247-259	13
α-helix	261-263	3
β-strand	266-268	3	32
β-strand	275-277	3	32
α-helix	288-310	23
α-helix	315-317	3
α-helix	319-345	27
α-helix	368-387	20
α-helix	393-402	10
α-helix	403-405	3
α-helix	409-415	7
α-helix	419-430	12
β-strand	448-450	3	33
β-strand	464-466	3	33
α-helix	468-470	3
α-helix	477-492	16
α-helix	534-547	14
α-helix	548-552	5
α-helix	556-561	6
α-helix	562-566	5
α-helix	571-580	10
α-helix	582-586	5
β-strand	588	1	34
α-helix	594-607	14
α-helix	615-620	6
β-strand	621-624	4	35
β-strand	633	1	34
α-helix	634-637	4
β-strand	639-642	4	35
α-helix	646-651	6
α-helix	654-690	37
α-helix	698-720	23
α-helix	721-728	8
α-helix	729-740	12
α-helix	748-761	14
α-helix	769-810	42
α-helix	827-864	38
α-helix	871-880	10

20 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Tubulin gamma-1 chain	a, b, c, d, e, f, g, h, i, j, k, l, m, n	protein	451	Homo sapiens	P23258 (AlphaFold model)
Gamma-tubulin complex component 5	J	protein	1024	Homo sapiens	Q96RT8 (AlphaFold model)
Gamma-tubulin complex component 4	I, K	protein	667	Homo sapiens	Q9UGJ1 (AlphaFold model)
Gamma-tubulin complex component 3	B, D, F, H, N	protein	907	Homo sapiens	Q96CW5 (AlphaFold model)
Gamma-tubulin complex component 2	A, C, E, G, M	protein	902	Homo sapiens	Q9BSJ2
Gamma-tubulin complex component 6	L	protein	1819	Homo sapiens	Q96RT7

Sequence of entity 1 (a, b, c, d, e, f, g, h, i, j, k, l, m, n), FASTA

>8Q62_1 Tubulin gamma-1 chain (chains a, b, c, d, e, f, g, h, i, j, k, l, m, n)
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE
MDTSREIVQQLIDEYHAATRPDYISWGTQEQ

Sequence of entity 2 (J), FASTA

>8Q62_2 Gamma-tubulin complex component 5 (chains J)
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHK
IEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDS
PSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSRE
DSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHS
NLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNI
IVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRT
YQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGV
AEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWI
VHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQG
PSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESV
QSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDF
HEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYL
QAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSIS
FENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDV
LLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNY
IMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAG
MEQS

Sequence of entity 3 (I, K), FASTA

>8Q62_3 Gamma-tubulin complex component 4 (chains I, K)
MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIE
QYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSIS
HVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCH
GVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQD
LRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSIL
KNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDF
YLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEY
HGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFK
YLLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQ
FSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQN
LGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGG
TLGSFGM

Sequence of entity 4 (B, D, F, H, N), FASTA

>8Q62_4 Gamma-tubulin complex component 3 (chains B, D, F, H, N)
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKK
ELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQ
ALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSL
LPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTG
GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWL
HNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLES
SLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILS
LVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQS
RKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFE
TSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI
LETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHY
LRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQY
YITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFD
QIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESI
PKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTR
GRRSSHT

Sequence of entity 5 (A, C, E, G, M), FASTA

>8Q62_5 Gamma-tubulin complex component 2 (chains A, C, E, G, M)
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG
RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV
KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH
DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ
EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK
ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR
KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM
AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI
SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID
DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL
EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL
SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT
AQ

Sequence of entity 6 (L), FASTA

>8Q62_6 Gamma-tubulin complex component 6 (chains L)
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPD
MSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGS
GPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQ
VMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNAD
LSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERV
GCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVL
IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLD
SLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVG
AVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWV
YSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGK
TINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEE
KELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERR
QAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALW
RIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGG
QGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFL
PVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPA
VATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQ
PTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTH
GHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNA
SIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGE
SVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVV
STRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPR
LPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDL
SPNWPLNSQEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSE
PPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVN
KAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNS
VLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGC
VSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVI
QGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSI
FSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQ
PHLEDFLLRINFNNYYQDA

Primary citation

Transition of human gamma-tubulin ring complex into a closed conformation during microtubule nucleation. Brito, C., Serna, M., Guerra, P. et al. Science (2024) 383:870-876. DOI 10.1126/science.adk6160 · PubMed

Other PDB entries of the same protein (UniProt P23258 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3CB2 2.3 Å, Crystal structure of human gamma-tubulin bound to GDP
1Z5V 2.71 Å, Crystal structure of human gamma-tubulin bound to GTPgammaS
1Z5W 3.0 Å, Crystal Structure of gamma-tubulin bound to GTP
8RX1 3.57 Å, CryoEM structure of the gTuRC-CM1dim complex
9SMX 3.67 Å, CM1-activated gTuRC in complex with nascent alpha-E254D mutant microtubules
6V5V 3.8 Å, Structure of gamma-tubulin in the native human gamma-tubulin ring complex
7AS4 4.13 Å, Recombinant human gTuRC
6V6S 4.3 Å, Structure of the native human gamma-tubulin ring complex
8VA2 4.5 Å, Symmetry expanded map of 2 gamma-tubulins bound to 2 alpha tubulins in gamma tubulin…
9H9P 4.5 Å, Spokes 12 and 13 of the human gamma-tubulin ring complex in complex with CDK5RAP2 and…
9QVN 4.7 Å, Cryo-EM reconstruction of the NEDD1 anchor protein bound to the gamma-tubulin ring complex
7QJ0 5.32 Å, Structure of recombinant human gamma-Tubulin Ring Complex 6-spoked assembly intermediate…

Browse structure collections

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