7AS4: Recombinant human gTuRC
Recombinant human gTuRC. Determined by electron microscopy at 4.13 Å resolution. Released 20 Jan 2021.
- Method
- Electron microscopy
- Resolution
- 4.13 Å
- Organism
- Homo sapiens
- Chains
- 33
- Atoms
- 120,779
- Mol. weight
- 2583.17 kDa
- Ligands
- GDP
- Released
- 20 Jan 2021
Explore 7AS4 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7AS4 contains 688 α-helices and 374 β-strands across 33 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 1: 17 helices, 19 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4-6 | 3 | 1 |
| β-strand | 7-10 | 4 | 2 |
| α-helix | 12-28 | 17 | |
| β-strand | 31 | 1 | 3 |
| β-strand | 36 | 1 | 4 |
| β-strand | 37 | 1 | 3 |
| α-helix | 38 | 1 | |
| β-strand | 52-54 | 3 | 5 |
| α-helix | 55 | 1 | |
| β-strand | 59 | 1 | 4 |
| β-strand | 60-62 | 3 | 5 |
| β-strand | 64-67 | 4 | 2 |
| α-helix | 73-78 | 6 | |
| β-strand | 91-92 | 2 | 2 |
| α-helix | 104-113 | 10 | |
| α-helix | 115-128 | 14 | |
| β-strand | 132-137 | 6 | 1 |
| α-helix | 146-160 | 15 | |
| β-strand | 165-168 | 4 | 1 |
| α-helix | 184-198 | 15 | |
| β-strand | 202-203 | 2 | 6 |
| α-helix | 207-217 | 11 | |
| α-helix | 224-244 | 21 | |
| α-helix | 253-260 | 8 | |
| β-strand | 268-269 | 2 | 6 |
| β-strand | 270-273 | 4 | 7 |
| α-helix | 290-298 | 9 | |
| β-strand | 303 | 1 | 7 |
| β-strand | 317-325 | 9 | 7 |
| α-helix | 330-343 | 14 | |
| β-strand | 358-361 | 4 | 7 |
| α-helix | 362-364 | 3 | |
| β-strand | 374-381 | 8 | 7 |
| α-helix | 384-401 | 18 | |
| α-helix | 409-414 | 6 | |
| α-helix | 419-439 | 21 | |
Chain 2: 17 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4-6 | 3 | 14 |
| β-strand | 7-10 | 4 | 15 |
| α-helix | 12-28 | 17 | |
| β-strand | 31 | 1 | 16 |
| β-strand | 36 | 1 | 17 |
| β-strand | 37 | 1 | 16 |
| α-helix | 38 | 1 | |
| β-strand | 52-54 | 3 | 18 |
| β-strand | 59 | 1 | 17 |
| β-strand | 60-62 | 3 | 18 |
| β-strand | 64-67 | 4 | 15 |
| α-helix | 73-78 | 6 | |
| β-strand | 91-92 | 2 | 15 |
| α-helix | 104-113 | 10 | |
| α-helix | 115-128 | 14 | |
| β-strand | 132-137 | 6 | 14 |
| α-helix | 146-160 | 15 | |
| β-strand | 165-168 | 4 | 14 |
| α-helix | 184-198 | 15 | |
| β-strand | 202-203 | 2 | 19 |
| α-helix | 207-217 | 11 | |
| α-helix | 224-244 | 21 | |
| α-helix | 253-260 | 8 | |
| β-strand | 263 | 1 | 20 |
| β-strand | 266 | 1 | 20 |
| β-strand | 268-269 | 2 | 19 |
| β-strand | 270-273 | 4 | 21 |
| α-helix | 290-298 | 9 | |
| β-strand | 303 | 1 | 21 |
| β-strand | 317-325 | 9 | 21 |
| α-helix | 330-332 | 3 | |
| α-helix | 335-343 | 9 | |
| β-strand | 358-361 | 4 | 21 |
| α-helix | 362-364 | 3 | |
| β-strand | 375-381 | 7 | 21 |
| α-helix | 384-401 | 18 | |
| α-helix | 409-414 | 6 | |
| α-helix | 419-439 | 21 | |
Chain 3: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-20 | 12 | |
| α-helix | 29-41 | 13 | |
| α-helix | 51-63 | 13 | |
| α-helix | 70-83 | 14 | |
| α-helix | 92-99 | 8 | |
Chain 4: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 68-80 | 13 | |
| α-helix | 84-96 | 13 | |
| α-helix | 106-112 | 7 | |
Chain 5: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 15-34 | 20 | |
| α-helix | 41-51 | 11 | |
| α-helix | 57-70 | 14 | |
Chain 6: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-34 | 21 | |
| α-helix | 41-51 | 11 | |
| α-helix | 57-70 | 14 | |
Chain 7: 23 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6 | 1 | |
| β-strand | 8-12 | 5 | 55 |
| β-strand | 17-20 | 4 | 55 |
| β-strand | 29-31 | 3 | 55 |
| β-strand | 35-38 | 4 | 56 |
| β-strand | 53-54 | 2 | 56 |
| α-helix | 56-60 | 5 | |
| β-strand | 65-68 | 4 | 56 |
| β-strand | 71 | 1 | 57 |
| β-strand | 76 | 1 | 57 |
| α-helix | 79-88 | 10 | |
| α-helix | 89-93 | 5 | |
| α-helix | 98-100 | 3 | |
| β-strand | 103-105 | 3 | 55 |
| α-helix | 113-125 | 13 | |
| β-strand | 131-134 | 4 | 55 |
| α-helix | 137-144 | 8 | |
| β-strand | 150-155 | 6 | 58 |
| β-strand | 160-166 | 7 | 58 |
| β-strand | 169-170 | 2 | 58 |
| α-helix | 172-174 | 3 | |
| α-helix | 175 | 1 | |
| β-strand | 176-178 | 3 | 58 |
| α-helix | 182-196 | 15 | |
| α-helix | 203-215 | 13 | |
| α-helix | 223-232 | 10 | |
| α-helix | 251-259 | 9 | |
| α-helix | 264-266 | 3 | |
| α-helix | 274-283 | 10 | |
| α-helix | 290-293 | 4 | |
| β-strand | 297-299 | 3 | 58 |
| α-helix | 302-305 | 4 | |
| α-helix | 309-320 | 12 | |
| β-strand | 329-330 | 2 | 58 |
| α-helix | 338-346 | 9 | |
| α-helix | 351-354 | 4 | |
| β-strand | 357-358 | 2 | 55 |
| α-helix | 359-364 | 6 | |
| α-helix | 367-369 | 3 | |
| α-helix | 370-373 | 4 | |
Chain A: 31 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 152-167 | 16 | |
| α-helix | 179-183 | 5 | |
| α-helix | 205-207 | 3 | |
| α-helix | 210-225 | 16 | |
| β-strand | 233-235 | 3 | 66 |
| α-helix | 236-237 | 2 | |
| β-strand | 246-248 | 3 | 66 |
| α-helix | 254-279 | 26 | |
| α-helix | 283-285 | 3 | |
| α-helix | 287-315 | 29 | |
| α-helix | 321-327 | 7 | |
| α-helix | 329-347 | 19 | |
| α-helix | 354-361 | 8 | |
| α-helix | 372-394 | 23 | |
| β-strand | 409-411 | 3 | 67 |
| β-strand | 432-434 | 3 | 67 |
| α-helix | 444-446 | 3 | |
| α-helix | 447-463 | 17 | |
| α-helix | 483-505 | 23 | |
| α-helix | 509-520 | 12 | |
| α-helix | 526-540 | 15 | |
| α-helix | 548-561 | 14 | |
| α-helix | 563-566 | 4 | |
| α-helix | 568-570 | 3 | |
| β-strand | 573-577 | 5 | 68 |
| β-strand | 616-620 | 5 | 68 |
| α-helix | 624-627 | 4 | |
| α-helix | 632-662 | 31 | |
| α-helix | 678-696 | 19 | |
| α-helix | 697-702 | 6 | |
| α-helix | 703-709 | 7 | |
| α-helix | 719-735 | 17 | |
| α-helix | 738-740 | 3 | |
| α-helix | 747-763 | 17 | |
| α-helix | 764-766 | 3 | |
| α-helix | 815-842 | 28 | |
| α-helix | 852-859 | 8 | |
25 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Tubulin gamma-1 chain | 1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z | protein | 447 | Homo sapiens | P23258 (AlphaFold model) |
| Gamma-tubulin complex component 3 | 3, B, D, F, H, N | protein | 907 | Homo sapiens | Q96CW5 (AlphaFold model) |
| Gamma-tubulin complex component 6 | 4, L | protein | 1819 | Homo sapiens | Q96RT7 (AlphaFold model) |
| Mitotic-spindle organizing protein 1 | 5, 6 | protein | 82 | Homo sapiens | Q08AG7 (AlphaFold model) |
| Actin, cytoplasmic 1 | 7 | protein | 374 | Homo sapiens | P60709 |
| Gamma-tubulin complex component 2 | A, C, E, G, M | protein | 902 | Homo sapiens | Q9BSJ2 |
| Gamma-tubulin complex component 4 | I, K | protein | 667 | Homo sapiens | Q9UGJ1 |
| Gamma-tubulin complex component 5 | J | protein | 1024 | Homo sapiens | Q96RT8 |
Sequence of entity 1 (1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z), FASTA
>7AS4_1 Tubulin gamma-1 chain (chains 1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z)
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE
MDTSREIVQQLIDEYHAATRPDYISWG
Sequence of entity 2 (3, B, D, F, H, N), FASTA
>7AS4_2 Gamma-tubulin complex component 3 (chains 3, B, D, F, H, N)
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKK
ELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQ
ALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSL
LPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTG
GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWL
HNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLES
SLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILS
LVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQS
RKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFE
TSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI
LETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHY
LRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQY
YITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFD
QIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESI
PKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTR
GRRSSHT
Sequence of entity 3 (4, L), FASTA
>7AS4_3 Gamma-tubulin complex component 6 (chains 4, L)
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPD
MSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGS
GPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQ
VMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNAD
LSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERV
GCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVL
IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLD
SLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVG
AVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWV
YSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGK
TINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEE
KELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERR
QAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALW
RIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGG
QGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFL
PVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPA
VATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQ
PTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTH
GHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNA
SIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGE
SVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVV
STRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPR
LPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDL
SPNWPLNSQEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSE
PPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVN
KAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNS
VLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGC
VSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVI
QGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSI
FSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQ
PHLEDFLLRINFNNYYQDA
Sequence of entity 4 (5, 6), FASTA
>7AS4_4 Mitotic-spindle organizing protein 1 (chains 5, 6)
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEAL
SSVIKELRKATEALKAAENMTS
Sequence of entity 5 (7), FASTA
>7AS4_5 Actin, cytoplasmic 1 (chains 7)
DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSK
RGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQ
IMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLA
GRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYE
LKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSG
GTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQE
YDESGPSIVHRKCF
Sequence of entity 6 (A, C, E, G, M), FASTA
>7AS4_6 Gamma-tubulin complex component 2 (chains A, C, E, G, M)
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG
RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV
KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH
DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ
EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK
ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR
KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM
AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI
SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID
DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL
EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL
SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT
AQ
Sequence of entity 7 (I, K), FASTA
>7AS4_7 Gamma-tubulin complex component 4 (chains I, K)
MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIE
QYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSIS
HVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCH
GVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQD
LRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSIL
KNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDF
YLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEY
HGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFK
YLLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQ
FSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQN
LGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGG
TLGSFGM
Sequence of entity 8 (J), FASTA
>7AS4_8 Gamma-tubulin complex component 5 (chains J)
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHK
IEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDS
PSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSRE
DSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHS
NLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNI
IVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRT
YQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGV
AEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWI
VHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQG
PSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESV
QSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDF
HEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYL
QAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSIS
FENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDV
LLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNY
IMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAG
MEQS
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 14 |
Primary citation
Assembly of the asymmetric human gamma-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase. Zimmermann, F., Serna, M., Ezquerra, A. et al. Sci Adv (2020) 6. DOI 10.1126/sciadv.abe0894 · PubMed
Other PDB entries of the same protein (UniProt P23258 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 3CB2 2.3 Å, Crystal structure of human gamma-tubulin bound to GDP
- 1Z5V 2.71 Å, Crystal structure of human gamma-tubulin bound to GTPgammaS
- 1Z5W 3.0 Å, Crystal Structure of gamma-tubulin bound to GTP
- 8RX1 3.57 Å, CryoEM structure of the gTuRC-CM1dim complex
- 9SMX 3.67 Å, CM1-activated gTuRC in complex with nascent alpha-E254D mutant microtubules
- 8Q62 3.72 Å, Early closed conformation of the g-tubulin ring complex
- 6V5V 3.8 Å, Structure of gamma-tubulin in the native human gamma-tubulin ring complex
- 6V6S 4.3 Å, Structure of the native human gamma-tubulin ring complex
- 8VA2 4.5 Å, Symmetry expanded map of 2 gamma-tubulins bound to 2 alpha tubulins in gamma tubulin…
- 9H9P 4.5 Å, Spokes 12 and 13 of the human gamma-tubulin ring complex in complex with CDK5RAP2 and…
- 9QVN 4.7 Å, Cryo-EM reconstruction of the NEDD1 anchor protein bound to the gamma-tubulin ring complex
- 7QJ0 5.32 Å, Structure of recombinant human gamma-Tubulin Ring Complex 6-spoked assembly intermediate…
Browse structure collections
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