Plasmodium falciparum Myosin A full-length, post-rigor state, complexed to the inhibitor KNX-115 and ATP-gamma-S. Determined by X-ray diffraction at 2.35 Å resolution. Released 5 Aug 2026.
Explore 9T7I in 3D Show helices and sheets RCSB PDB PDBe
9T7I contains 61 α-helices and 37 β-strands across 3 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 11-14 | 4 | |
| β-strand | 24 | 1 | 1 |
| α-helix | 29 | 1 | |
| β-strand | 30 | 1 | 1 |
| α-helix | 31 | 1 | |
| β-strand | 35-38 | 4 | 2 |
| α-helix | 42-46 | 5 | |
| β-strand | 53-57 | 5 | 2 |
| β-strand | 66-72 | 7 | 2 |
| β-strand | 80-82 | 3 | 2 |
| α-helix | 84-86 | 3 | |
| β-strand | 87-88 | 2 | 2 |
| α-helix | 96-98 | 3 | |
| β-strand | 101 | 1 | 3 |
| α-helix | 102-104 | 3 | |
| α-helix | 110-122 | 13 | |
| β-strand | 127-130 | 4 | 3 |
| β-strand | 133-137 | 5 | 3 |
| α-helix | 148-156 | 9 | |
| α-helix | 160-162 | 3 | |
| α-helix | 164-165 | 2 | |
| α-helix | 167-181 | 15 | |
| β-strand | 185-191 | 7 | 3 |
| α-helix | 197-208 | 12 | |
| α-helix | 218-235 | 18 | |
| β-strand | 236-237 | 2 | 4 |
| β-strand | 245-246 | 2 | 4 |
| β-strand | 249-256 | 8 | 3 |
| β-strand | 262-270 | 9 | 3 |
| α-helix | 274-277 | 4 | |
| β-strand | 287 | 1 | 4 |
| α-helix | 288-296 | 9 | |
| α-helix | 299-305 | 7 | |
| α-helix | 328-341 | 14 | |
| α-helix | 346-363 | 18 | |
| β-strand | 367-370 | 4 | 5 |
| β-strand | 378-381 | 4 | 5 |
| α-helix | 383-385 | 3 | |
| α-helix | 386-395 | 10 | |
| α-helix | 400-408 | 9 | |
| β-strand | 409-414 | 6 | 6 |
| β-strand | 417-422 | 6 | 6 |
| α-helix | 425-455 | 31 | |
| β-strand | 465-471 | 7 | 3 |
| β-strand | 479 | 1 | 7 |
| α-helix | 481-512 | 32 | |
| α-helix | 525-532 | 8 | |
| α-helix | 538-547 | 10 | |
| α-helix | 553-563 | 11 | |
| β-strand | 570-572 | 3 | 7 |
| β-strand | 580-585 | 6 | 7 |
| β-strand | 588-593 | 6 | 7 |
| α-helix | 597-601 | 5 | |
| α-helix | 608-614 | 7 | |
| α-helix | 619-624 | 6 | |
| α-helix | 628-631 | 4 | |
| α-helix | 637-639 | 3 | |
| α-helix | 641-657 | 17 | |
| β-strand | 660-667 | 8 | 3 |
| α-helix | 680-689 | 10 | |
| α-helix | 692-700 | 9 | |
| β-strand | 705-708 | 4 | 8 |
| α-helix | 709-715 | 7 | |
| α-helix | 717-720 | 4 | |
| α-helix | 721-725 | 5 | |
| α-helix | 731-742 | 12 | |
| α-helix | 746-748 | 3 | |
| β-strand | 749-751 | 3 | 8 |
| β-strand | 755-758 | 4 | 8 |
| α-helix | 760-772 | 13 | |
| α-helix | 775-777 | 3 | |
| α-helix | 778-799 | 22 | |
| α-helix | 801-817 | 17 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 30-38 | 9 | |
| β-strand | 40 | 1 | 9 |
| β-strand | 43 | 1 | 9 |
| β-strand | 44-45 | 2 | 10 |
| α-helix | 46-55 | 10 | |
| α-helix | 62-72 | 11 | |
| β-strand | 75-76 | 2 | 10 |
| α-helix | 78-87 | 10 | |
| α-helix | 95-98 | 4 | |
| α-helix | 100-104 | 5 | |
| β-strand | 112-114 | 3 | 11 |
| α-helix | 115-124 | 10 | |
| α-helix | 128-130 | 3 | |
| α-helix | 131-139 | 9 | |
| β-strand | 146-148 | 3 | 11 |
| α-helix | 149-157 | 9 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 6-16 | 11 | |
| β-strand | 22-23 | 2 | 12 |
| α-helix | 25-34 | 10 | |
| α-helix | 41-45 | 5 | |
| β-strand | 51-52 | 2 | 12 |
| α-helix | 53-63 | 11 | |
| α-helix | 88-96 | 9 | |
| α-helix | 103-112 | 10 | |
| α-helix | 123-132 | 10 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Myosin-A | A | protein | 818 | Plasmodium falciparum | Q8IDR3 (AlphaFold model) |
| Myosin A tail domain interacting protein | B | protein | 204 | Plasmodium falciparum | Q8I4W8 (AlphaFold model) |
| Myosin essential light chain ELC | E | protein | 134 | Plasmodium falciparum | Q8IJM4 (AlphaFold model) |
>9T7I_1 Myosin-A (chains A) MAVTNEEIKTASKIVRRVSNVEAFDKSGSVFKGYQIWTDISPTIENDPNIMFVKCVVQQG SKKEKLTVVQIDPPGTGTPYDIDPTHAWNCNSQVDPMSFGDIGLLNHTNIPCVLDFLKHR YLKNQIYTTAVPLIVAINPYKDLGNTTNEWIRRYRDTADHTKLPPHVFTCAREALSNLHG VNKSQTIIVSGESGAGKTEATKQIMRYFASSKSGNMDLRIQTAIMAANPVLEAFGNAKTI RNNNSSRFGRFMQLVISHEGGIRYGSVVAFLLEKSRIITQDDNERSYHIFYQFLKGANST MKSKFGLKGVTEYKLLNPNSTEVSGVDDVKDFEEVIESLKNMELSESDIEVIFSIVAGIL TLGNVRLIEKQEAGLSDAAAIMDEDMGVFNKACELMYLDPELIKREILIKVTVAGGTKIE GRWNKNDAEVLKSSLCKAMYEKLFLWIIRHLNSRIEPEGGFKTFMGMLDIFGFEVFKNNS LEQLFINITNEMLQKNFVDIVFERESKLYKDEGISTAELKYTSNKEVINVLCEKGKSVLS YLEDQCLAPGGTDEKFVSSCATNLKENNKFTPAKVASNKNFIIQHTIGPIQYCAESFLLK NKDVLRGDLVEVIKDSPNPIVQQLFEGQVIEKGKIAKGSLIGSQFLNQLTSLMNLINSTE PHFIRCIKPNENKKPLEWCEPKILIQLHALSILEALVLRQLGYSYRRTFEEFLYQYKFVD IAAAEDSSVENQNKCVNILKLSGLSESMYKIGKSMVFLKQEGAKILTKIQREKLVEWENC VSVIEAAILKHKYKQKVNKNIPSLLRVQAHIRKKMVAQ
>9T7I_2 Myosin A tail domain interacting protein (chains B) MKQECNVCYFNLPDPESTLGPYDNELNYFTWGPGFEYEPEPQRKPLSIEESFENSEESEE SVADIQQLEEKVDESDVRIYFNEKSSGGKISIDNASYNARKLGLAPSSIDEKKIKELYGD NLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEA IDALNAFSSEDNIDYKLFCEDILQ
>9T7I_3 Myosin essential light chain ELC (chains E) MASDMEEKFREAFILFSSCSDHIEMYKFFELMNSFGIILTNDEKAALPNDINMDYWLNFA KKHYNYEQPFKHINNVNEQNTNVQIKIDNFLGIMKALDTRLTESDLNILLQITNPENKST LNLKTVSQKLTESI
| ID | Name | Formula | Copies |
|---|---|---|---|
| A1JT8 | 4-methoxy-~{N}-[(3-thiophen-2-yl-1~{H}-pyrazol-4-yl)methyl]benzenesulfonamide | C15 H15 N3 O3 S2 | 1 |
| MG | Magnesium ion | Mg | 1 |
| AGS | Phosphothiophosphoric acid-adenylate ester | C10 H16 N5 O12 P3 S | 1 |
Water and common crystallization additives (GOL) are not listed.
Plasmodium falciparum Myosin A full-length, post-rigor state, complexed to the inhibitor KNX-115 and ATP-gamma-S. Moussaoui, D., Spudich, J.A., Trybus, K.M. et al. To be published.
Other PDB entries of the same protein (UniProt Q8IDR3 (AlphaFold model), which also has an AlphaFold model), best resolution first:
MolViewer shows 9T7I directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.