G0SC29: Ribosome assembly protein 4 (CTHT_0055700)

Ribosome assembly protein 4 (CTHT_0055700) is a 517-residue protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: G0SC29.

Gene
CTHT_0055700
Organism
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Length
517 residues
Mean pLDDT
93.4
Model
AF-G0SC29-F1 v6
Model created
1 Aug 2025
PDB structures
12

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Model confidence (pLDDT)

The mean pLDDT of this model is 93.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate89%
70 to 90Confident: backbone generally right8%
50 to 70Low: treat with caution2%
Below 50Very low: often disordered regions2%

What pLDDT means and how to read it

Function

Involved in ribosome biogenesis. Required for processing and efficient intra-nuclear transport of pre-60S ribosomal subunits. Interacts with the AAA-ATPase Midasin, which is essential for the ATP-dependent dissociation of a group of nonribosomal factors from the pre-60S particle

Subunit structure

Associates with the pre-60S ribosomal particle. Interacts (via WD repeats) with uL18. Interacts (via UBL domain) with MDN1 (via VWFA/MIDAS domain). Interacts (via WD repeats) with NSA2

Subcellular location

Nucleus, nucleolus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4WJSX-ray1.8 ÅA=33-517
6QTAX-ray1.89 ÅB=30-128
8PV7EM2.12 ÅCh=1-517
8PVLEM2.19 ÅCh=1-517
8PVKEM2.55 ÅCh=1-517
8PV1EM2.56 ÅCh=1-517
8PV2EM2.63 ÅCh=1-116, Ch=118-517
8PV3EM2.8 ÅCh=1-517
8PV5EM2.86 ÅCh=1-517
8PV4EM2.9 ÅCh=1-517
8PV8EM2.91 ÅCh=1-517
8PV6EM2.94 ÅCh=1-517

More AlphaFold highlights

About this viewer

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