Thioredoxin 1 (trxA) is a 109-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0AA25.
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The mean pLDDT of this model is 95.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 95% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions
Monomer. Interacts with bacteriophage T3 DNA polymerase
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4HUA | X-ray | 1.1 Å | A=2-109 |
| 5HR3 | X-ray | 1.1 Å | A/B=1-109 |
| 5HR2 | X-ray | 1.2 Å | A=1-109 |
| 5HR0 | X-ray | 1.31 Å | A/B=1-109 |
| 4HU7 | X-ray | 1.4 Å | A/B=2-109 |
| 4HU9 | X-ray | 1.55 Å | A=2-109 |
| 4X43 | X-ray | 1.65 Å | A/B/C=2-109 |
| 2TRX | X-ray | 1.68 Å | A/B=2-109 |
| 6Y4Y | X-ray | 1.75 Å | A/B/C/D=1-109 |
| 1KEB | X-ray | 1.8 Å | A/B=2-109 |
| 2EIQ | X-ray | 1.9 Å | A/B=2-109 |
| 6Y4Z | X-ray | 1.9 Å | A/B/C/D=1-109 |
| 2TIR | X-ray | 2.0 Å | A=2-109 |
| 3DYR | X-ray | 2.0 Å | A/B=2-109 |
| 6LUR | X-ray | 2.0 Å | A/B/C/D/E/F/G/H=1-109 |
| 6GD1 | X-ray | 2.01 Å | A/B=1-109 |
| 1X9M | X-ray | 2.1 Å | B=2-109 |
| 8S2N | X-ray | 2.11 Å | C=2-109 |
| 5HR1 | X-ray | 2.14 Å | A/B/C/D/E/F/G=1-109 |
| 1SL1 | X-ray | 2.2 Å | B=2-109 |
Showing 20 of 78 experimental structures (best resolution first).
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