Gelsolin (Gsn) is a 780-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P13020.
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The mean pLDDT of this model is 88.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 75% |
| 70 to 90 | Confident: backbone generally right | 16% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (By similarity). Plays a role in ciliogenesis (By similarity)
Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN and TMSB4X (By similarity). Interacts with the inactive form of EIF2AK2/PKR. Interacts with FLII (PubMed:37126682)
Cytoplasm, cytoskeleton, Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6I4E | X-ray | 1.22 Å | G=50-174 |
| 6I4D | X-ray | 1.24 Å | G=50-174 |
| 4CBU | X-ray | 1.3 Å | G=50-174 |
| 5MVV | X-ray | 1.4 Å | G=50-174 |
| 6I4H | X-ray | 1.4 Å | G=50-174 |
| 6I4F | X-ray | 1.5 Å | G=50-174 |
| 6I4J | X-ray | 1.5 Å | G=50-174 |
| 6I4K | X-ray | 1.83 Å | G=50-174 |
| 6I4L | X-ray | 1.83 Å | G=50-174 |
| 6I4M | X-ray | 1.87 Å | G=50-174 |
| 6I4I | X-ray | 1.9 Å | G=50-174 |
| 6I4G | X-ray | 2.0 Å | G/H=50-174 |
| 4CBX | X-ray | 2.2 Å | G=50-174 |
| 4CBW | X-ray | 2.5 Å | G=50-174 |
| 1NPH | X-ray | 3.0 Å | A=439-767 |
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