Endothelin receptor type B (EDNRB) is a 442-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P24530.
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The mean pLDDT of this model is 75.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 45% |
| 70 to 90 | Confident: backbone generally right | 21% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 27% |
What pLDDT means and how to read it
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6IGK | X-ray | 2.0 Å | A=66-407 |
| 5X93 | X-ray | 2.2 Å | A=66-303, A=311-407 |
| 5GLI | X-ray | 2.5 Å | A=66-303, A=313-395 |
| 6IGL | X-ray | 2.7 Å | A=66-407 |
| 6K1Q | X-ray | 2.7 Å | A=66-303, A=311-407 |
| 5GLH | X-ray | 2.8 Å | A=66-303, A=313-395 |
| 8IY5 | EM | 2.8 Å | R=27-442 |
| 8HBD | EM | 2.99 Å | R=27-424 |
| 6LRY | X-ray | 3.0 Å | A=66-407 |
| 8XVE | EM | 3.0 Å | R=67-406 |
| 8IY6 | EM | 3.13 Å | R=27-442 |
| 8XGR | EM | 3.2 Å | R=27-442 |
| 8XWP | EM | 3.21 Å | R=66-407 |
| 8XVH | EM | 3.26 Å | R=67-406 |
| 8HCX | EM | 3.5 Å | C=27-424 |
| 5XPR | X-ray | 3.6 Å | A=66-303, A=311-407 |
| 8ZRT | EM | 3.62 Å | R=66-407 |
| 8XWQ | EM | 4.6 Å | R=66-407 |
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