Ribosome assembly protein 4 (RSA4) is a 515-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P25382.
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The mean pLDDT of this model is 91.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 76% |
| 70 to 90 | Confident: backbone generally right | 18% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Involved in ribosome biogenesis. Required for processing and efficient intra-nuclear transport of pre-60S ribosomal subunits. Interacts with the AAA-ATPase Midasin (MDN1/REA1), which is essential for the ATP-dependent dissociation of a group of nonribosomal factors from the pre-60S particle
Associates with the pre-60S ribosomal particle (PubMed:16702403, PubMed:18658244, PubMed:19737519). Interacts (via WD repeats) with uL18 (RPL5) (PubMed:25404745). Interacts (via UBL domain) with MDN1 (via VWFA/MIDAS domain) (PubMed:19737519, PubMed:20542003). Interacts (via WD repeats) with NSA2 (PubMed:25404745)
Nucleus, nucleolus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7UOO | EM | 2.34 Å | x=1-515 |
| 7V08 | EM | 2.36 Å | x=1-515 |
| 7UQB | EM | 2.43 Å | x=2-515 |
| 7UQZ | EM | 2.44 Å | x=1-515 |
| 4WJU | X-ray | 2.8 Å | A/B=1-515 |
| 7UG6 | EM | 2.9 Å | x=2-515 |
| 6YLG | EM | 3.0 Å | x=1-515 |
| 3JCT | EM | 3.08 Å | x=1-515 |
| 6YLH | EM | 3.1 Å | x=1-515 |
| 7OHQ | EM | 3.1 Å | x=1-515 |
| 7BT6 | EM | 3.12 Å | x=1-515 |
| 4WJV | X-ray | 3.2 Å | A/B/C/D=137-515 |
| 6M62 | EM | 3.2 Å | x=1-515 |
| 7BTB | EM | 3.22 Å | x=1-515 |
| 7OH3 | EM | 3.4 Å | x=1-515 |
| 6FT6 | EM | 3.9 Å | x=1-515 |
| 6YLF | EM | 4.2 Å | xP1=1-515 |
| 7OHT | EM | 4.7 Å | x=1-515 |
| 4V7F | EM | 8.7 Å | q=1-515 |
| 5JCS | EM | 9.5 Å | q=1-515 |
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