P60616: Alpha-bungarotoxin isoform V31

Alpha-bungarotoxin isoform V31 is a 95-residue protein from Bungarus multicinctus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P60616.

Organism
Bungarus multicinctus
Length
95 residues
Mean pLDDT
90.4
Model
AF-P60616-F1 v6
Model created
1 Aug 2025
PDB structures
8

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate74%
70 to 90Confident: backbone generally right16%
50 to 70Low: treat with caution11%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission

Subunit structure

Monomer in solution, homodimer in crystal state

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
1HC9X-ray1.8 ÅA=22-95
2QC1X-ray1.94 ÅA=22-95
8VY8X-ray2.4 ÅA/B/E/G=22-95
5HBTX-ray2.61 ÅA=22-95
4UY2X-ray2.7 ÅC/D=22-95
5HBVX-ray2.7 ÅA=22-95
7KOOEM3.0 ÅF/G/H/I/J=22-92
4HQPX-ray3.51 ÅF/G/H/I/J=22-94

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