ATR-interacting protein (ATRIP) is a 791-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8WXE1.
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The mean pLDDT of this model is 68.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 33% |
| 70 to 90 | Confident: backbone generally right | 25% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 35% |
What pLDDT means and how to read it
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein
Interacts with ATR (By similarity). Heterodimer with ATR. The heterodimer binds the RPA complex and is then recruited to single-stranded DNA. Interacts with CEP164 (via N-terminus). Interacts with CINP
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4NB3 | X-ray | 1.35 Å | C/D=54-67 |
| 7XV4 | X-ray | 1.6 Å | B=53-69 |
| 4IGK | X-ray | 1.75 Å | C/D=237-243 |
| 9L4D | EM | 3.79 Å | C/D=301-791 |
| 9L43 | EM | 3.83 Å | C/D=1-791 |
| 9L45 | EM | 3.95 Å | C/D=1-791 |
| 9L4C | EM | 4.06 Å | C/D=1-791 |
| 5YZ0 | EM | 4.7 Å | C/D=1-791 |
| 9L4F | EM | 6.22 Å | C/D=1-791 |
| 9L46 | EM | 6.29 Å | C/D=1-791 |
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