Heme-binding protein 2 (HEBP2) is a 205-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9Y5Z4.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 85.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 72% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 13% |
What pLDDT means and how to read it
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions
Monomer. Interacts with LRPPRC (PubMed:11827465). May interact with BCL2L1; an interaction with BCL2L1 was observed using a peptide, but not with the full-length protein (PubMed:21639858). The full-length protein would have to undergo a major conformation change for the interaction to occur (PubMed:21639858). Interacts with PDCD6 (PubMed:27784779)
Cytoplasm, Mitochondrion
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3R8J | X-ray | 1.6 Å | A/B=2-205 |
| 3R85 | X-ray | 1.95 Å | E/F/G/H=147-172 |
| 5GQQ | X-ray | 2.2 Å | A/B=20-197 |
| 3R8K | X-ray | 2.85 Å | A/B/C/D=2-205 |
| 4AYZ | X-ray | 3.5 Å | A/B=1-205 |
| 4B0Y | X-ray | 3.5 Å | A=1-205 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.