SH2 domain of CT10-Regulated Kinase. Determined by solution NMR. Released 10 Nov 2006.
Explore 2EYV in 3D Show helices and sheets RCSB PDB PDBe
2EYV contains 2 α-helices and 7 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 16 | 1 | 1 |
| α-helix | 20-26 | 7 | |
| β-strand | 35-38 | 4 | 1 |
| β-strand | 47-53 | 7 | 1 |
| β-strand | 56-63 | 8 | 1 |
| β-strand | 87-89 | 3 | 1 |
| β-strand | 92-94 | 3 | 1 |
| α-helix | 97-103 | 7 | |
| β-strand | 117 | 1 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| v-crk sarcoma virus CT10 oncogene homolog isoform a | A | protein | 124 | Homo sapiens | P46108 (AlphaFold model) |
>2EYV_1 v-crk sarcoma virus CT10 oncogene homolog isoform a (chains A) GAMGDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYI INSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRS RQGR
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Kobashigawa, Y., Sakai, M., Naito, M. et al. Nat Struct Mol Biol (2007) 14:503-510. DOI 10.1038/nsmb1241 · PubMed
Other PDB entries of the same protein (UniProt P46108 (AlphaFold model), which also has an AlphaFold model), best resolution first:
MolViewer shows 2EYV directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.