4DXT: Human SUN2

Human SUN2 (AA 522-717). Determined by X-ray diffraction at 2.22 Å resolution. Released 6 Jun 2012.

Method: X-ray diffraction
Resolution: 2.22 Å
Organism: Homo sapiens
Chains: 1
Atoms: 1,705
Mol. weight: 22.18 kDa
Released: 6 Jun 2012

Explore 4DXT in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4DXT contains 7 α-helices and 13 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 7 helices, 13 β-strands

Element	Residues	Length	Sheet
α-helix	525-540	16
α-helix	552-554	3
β-strand	557-563	7	1
β-strand	566	1	2
α-helix	571-574	4
α-helix	588-592	5
β-strand	602-605	4	2
β-strand	609-619	11	1
β-strand	620-627	8	3
α-helix	631-633	3
α-helix	635-637	3
β-strand	643	1	4
β-strand	645-651	7	1
α-helix	659	1
β-strand	660-666	7	1
β-strand	674-678	5	3
β-strand	687-694	8	1
β-strand	697	1	4
β-strand	703-706	4	2
β-strand	708-714	7	3

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
SUN domain-containing protein 2	A	protein	198	Homo sapiens	Q9UH99 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>4DXT_1 SUN domain-containing protein 2 (chains A)
GPGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGI
PLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTI
SSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWG
HPEYTCIYRFRVHGEPAH

Primary citation

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins. Sosa, B.A., Rothballer, A., Kutay, U. et al. Cell (2012) 149:1035-1047. DOI 10.1016/j.cell.2012.03.046 · PubMed

Other PDB entries of the same protein (UniProt Q9UH99 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6WMD 1.5 Å, Human Sun2-KASH4 complex
6WME 1.53 Å, Human Sun2-KASH3 complex
6WMG 1.9 Å, Human Sun2 (500-717)
4DXR 2.32 Å, Human SUN2-KASH1 complex
3UNP 2.39 Å, Structure of human SUN2 SUN domain
6WMF 2.6 Å, Human Sun2-KASH5 complex
4DXS 2.71 Å, Human SUN2-KASH2 complex
4FI9 3.05 Å, Structure of human SUN-KASH complex

Browse structure collections

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