6DD7: Ultraviolet-B receptor UVR8

Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction. Determined by X-ray diffraction at 2.0 Å resolution. Released 18 Jul 2018.

Method: X-ray diffraction
Resolution: 2.0 Å
Organism: Arabidopsis thaliana
Chains: 4
Atoms: 12,160
Mol. weight: 163.5 kDa
Released: 18 Jul 2018

Explore 6DD7 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6DD7 contains 29 α-helices and 115 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 6 helices, 30 β-strands

Element	Residues	Length	Sheet
β-strand	17-22	6	1
β-strand	26-31	6	1
β-strand	35-40	6	1
β-strand	55-60	6	1
α-helix	61	1
α-helix	62-64	3
β-strand	69	1	2
β-strand	73-74	2	3
β-strand	78-80	3	3
β-strand	83	1	2
β-strand	90-93	4	3
β-strand	108-113	6	3
α-helix	115-117	3
β-strand	122-127	6	4
β-strand	131-136	6	4
β-strand	141-145	5	4
β-strand	160-165	6	4
α-helix	167-169	3
β-strand	174-179	6	5
β-strand	183-188	6	5
β-strand	193-197	5	5
β-strand	212-217	6	5
β-strand	226-231	6	6
β-strand	235-240	6	6
β-strand	245-249	5	6
β-strand	264-269	6	6
α-helix	271-273	3
β-strand	278-283	6	7
β-strand	287-292	6	7
β-strand	297-301	5	7
β-strand	316-322	7	7
β-strand	330-335	6	8
β-strand	339-344	6	8
β-strand	349-353	5	8
β-strand	368-373	6	8
α-helix	375-377	3

Chain B: 7 helices, 28 β-strands

Element	Residues	Length	Sheet
β-strand	17-22	6	9
β-strand	26-31	6	9
β-strand	36-40	5	9
β-strand	55-60	6	9
α-helix	62-64	3
β-strand	69-74	6	10
β-strand	78-83	6	10
β-strand	89-93	5	10
α-helix	96-98	3
β-strand	108-113	6	10
α-helix	115-117	3
β-strand	122-127	6	11
β-strand	131-136	6	11
β-strand	141-145	5	11
β-strand	160-165	6	11
α-helix	167-169	3
β-strand	174-179	6	12
β-strand	183-188	6	12
β-strand	193-197	5	12
β-strand	212-217	6	12
β-strand	226-231	6	13
β-strand	235-240	6	13
β-strand	245-249	5	13
β-strand	264-269	6	13
α-helix	271-273	3
β-strand	278-283	6	14
β-strand	287-292	6	14
β-strand	297-301	5	14
β-strand	316-321	6	14
α-helix	325-327	3
α-helix	328-329	2
β-strand	330-335	6	15
β-strand	339-344	6	15
β-strand	349-353	5	15
β-strand	368-373	6	15

Chain C: 7 helices, 29 β-strands

Element	Residues	Length	Sheet
β-strand	17-22	6	16
β-strand	26-31	6	16
β-strand	35-40	6	16
β-strand	55-60	6	16
α-helix	62-64	3
β-strand	71-74	4	17
β-strand	78-83	6	17
β-strand	88-93	6	17
α-helix	96-98	3
β-strand	108	1	17
β-strand	113	1	17
α-helix	115-117	3
β-strand	122-127	6	18
β-strand	131-136	6	18
β-strand	141-145	5	18
β-strand	160-165	6	18
α-helix	167-169	3
β-strand	174-179	6	19
β-strand	183-188	6	19
β-strand	193-197	5	19
β-strand	212-217	6	19
α-helix	224-225	2
β-strand	226-231	6	20
β-strand	235-240	6	20
β-strand	245-249	5	20
β-strand	264-269	6	20
α-helix	271-273	3
β-strand	278-283	6	21
β-strand	287-292	6	21
β-strand	297-301	5	21
β-strand	316-321	6	21
α-helix	325-327	3
β-strand	330-335	6	22
β-strand	339-344	6	22
β-strand	349-353	5	22
β-strand	368-373	6	22

Chain D: 9 helices, 28 β-strands

Element	Residues	Length	Sheet
β-strand	17-22	6	23
β-strand	26-31	6	23
β-strand	35-40	6	23
β-strand	55-60	6	23
α-helix	62-64	3
β-strand	69-74	6	24
β-strand	78-83	6	24
β-strand	88-93	6	24
α-helix	96-98	3
β-strand	108-113	6	24
α-helix	115-117	3
β-strand	122-127	6	25
β-strand	131-136	6	25
β-strand	141-145	5	25
β-strand	160-165	6	25
α-helix	167-169	3
β-strand	174-179	6	26
β-strand	183-188	6	26
β-strand	193-197	5	26
β-strand	212-217	6	26
β-strand	226-231	6	27
β-strand	235-240	6	27
β-strand	245-249	5	27
β-strand	264-269	6	27
α-helix	272-275	4
β-strand	278-283	6	28
β-strand	287-292	6	28
β-strand	297-301	5	28
β-strand	316-322	7	28
α-helix	323	1
α-helix	325-327	3
α-helix	328-329	2
β-strand	330-335	6	29
β-strand	339-344	6	29
β-strand	349-353	5	29
β-strand	368-373	6	29
α-helix	375-377	3

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Ultraviolet-B receptor UVR8	A, B, C, D	protein	377	Arabidopsis thaliana	Q9FN03 (AlphaFold model)

Sequence of entity 1 (A, B, C, D), FASTA

>6DD7_1 Ultraviolet-B receptor UVR8 (chains A, B, C, D)
PPRKVLIISAGASHSVALLSGDIVCSWGRGEDGQLGHGDAEDRPSPTQLSALDGHQIVSV
TCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACGDSHC
LAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGD
LYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSK
YGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGN
NLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPK
IIEALSVDGLEHHHHHH

Primary citation

Crystal-on-crystal chips for in situ serial diffraction at room temperature. Ren, Z., Ayhan, M., Bandara, S. et al. Lab Chip (2018) 18:2246-2256. DOI 10.1039/c8lc00489g · PubMed

Other PDB entries of the same protein (UniProt Q9FN03 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6QTS 1.11 Å, Crystal structure of a mutant Arabidopsis WD40 domain in complex with a photoreceptor
6QTQ 1.3 Å, Crystal structure of an Arabidopsis WD40 domain in complex with photoreceptor
6XZL 1.39 Å, Arabidopsis UV-B photoreceptor UVR8 mutant D96N D107N
4NBM 1.61 Å, Crystal structure of UVB photoreceptor UVR8 and light-induced structural changes at 180K
4NAA 1.67 Å, Crystal structure of UVB photoreceptor UVR8 from Arabidopsis thaliana and UV-induced…
4D9S 1.7 Å, Crystal structure of Arabidopsis thaliana UVR8 (UV Resistance locus 8)
4NC4 1.75 Å, Crystal structure of photoreceptor AtUVR8 mutant W285F and light-induced structural…
6XZN 1.75 Å, Arabidopsis UV-B photoreceptor UVR8 mutant G101S W285A
4DNU 1.76 Å, Crystal structure of the W285A mutant of UVB-resistance protein UVR8
4DNW 1.77 Å, Crystal structure of UVB-resistance protein UVR8
4DNV 2.0 Å, Crystal structure of the W285F mutant of UVB-resistance protein UVR8
8GQE 2.0 Å, Crystal structure of the W285A mutant of UVR8 in complex with RUP2

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