7R5K: Human nuclear pore complex

Human nuclear pore complex (constricted). Determined by electron microscopy at 12.0 Å resolution. Released 22 Jun 2022.

Method: Electron microscopy
Resolution: 12.0 Å
Organism: Homo sapiens
Chains: 101
Atoms: 617,133
Mol. weight: 12078.34 kDa
Released: 22 Jun 2022

Explore 7R5K in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7R5K contains 3,733 α-helices and 2,905 β-strands across 95 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 00: 43 helices, 0 β-strands

Element	Residues	Length
α-helix	5-17	13
α-helix	22-37	16
α-helix	42-53	12
α-helix	60-71	12
α-helix	76-89	14
α-helix	94-105	12
α-helix	112-122	11
α-helix	129-139	11
α-helix	143-158	16
α-helix	166-177	12
α-helix	181-191	11
α-helix	195-198	4
α-helix	201-215	15
α-helix	224-249	26
α-helix	252-269	18
α-helix	277-303	27
α-helix	309-325	17
α-helix	327-329	3
α-helix	340-341	2
α-helix	342-362	21
α-helix	368-374	7
α-helix	379-389	11
α-helix	412-415	4
α-helix	416-429	14
α-helix	434-444	11
α-helix	450-451	2
α-helix	453-460	8
α-helix	476-478	3
α-helix	481-503	23
α-helix	526-539	14
α-helix	547-562	16
α-helix	572-586	15
α-helix	592-616	25
α-helix	623-625	3
α-helix	637-639	3
α-helix	645-647	3
α-helix	649-661	13
α-helix	664-674	11
α-helix	677-692	16
α-helix	701-727	27
α-helix	731-733	3
α-helix	739-754	16
α-helix	755-757	3

Chain 01: 45 helices, 0 β-strands

Element	Residues	Length
α-helix	5-17	13
α-helix	22-37	16
α-helix	42-53	12
α-helix	60-71	12
α-helix	76-89	14
α-helix	94-104	11
α-helix	112-122	11
α-helix	129-139	11
α-helix	140-142	3
α-helix	143-158	16
α-helix	166-177	12
α-helix	181-191	11
α-helix	195-198	4
α-helix	201-215	15
α-helix	224-249	26
α-helix	252-269	18
α-helix	277-303	27
α-helix	309-325	17
α-helix	327-329	3
α-helix	331-333	3
α-helix	340-341	2
α-helix	342-362	21
α-helix	368-376	9
α-helix	379-389	11
α-helix	412-415	4
α-helix	416-429	14
α-helix	434-444	11
α-helix	450-451	2
α-helix	453-460	8
α-helix	476-478	3
α-helix	481-503	23
α-helix	526-539	14
α-helix	547-562	16
α-helix	572-586	15
α-helix	592-616	25
α-helix	623-625	3
α-helix	637-639	3
α-helix	645-647	3
α-helix	649-661	13
α-helix	664-674	11
α-helix	677-692	16
α-helix	701-727	27
α-helix	731-733	3
α-helix	739-754	16
α-helix	755-757	3

Chain 02: 46 helices, 0 β-strands

Element	Residues	Length
α-helix	5-17	13
α-helix	22-26	5
α-helix	29-37	9
α-helix	42-53	12
α-helix	60-71	12
α-helix	76-89	14
α-helix	94-105	12
α-helix	112-122	11
α-helix	129-139	11
α-helix	140-142	3
α-helix	143-158	16
α-helix	166-177	12
α-helix	181-191	11
α-helix	195-198	4
α-helix	201-215	15
α-helix	224-249	26
α-helix	252-269	18
α-helix	277-303	27
α-helix	309-325	17
α-helix	327-329	3
α-helix	340-341	2
α-helix	342-362	21
α-helix	368-376	9
α-helix	379-389	11
α-helix	412-415	4
α-helix	416-429	14
α-helix	434-444	11
α-helix	450-451	2
α-helix	453-460	8
α-helix	476-478	3
α-helix	481-503	23
α-helix	526-539	14
α-helix	547-562	16
α-helix	572-586	15
α-helix	592-616	25
α-helix	623-625	3
α-helix	634-636	3
α-helix	637-639	3
α-helix	645-647	3
α-helix	649-661	13
α-helix	664-674	11
α-helix	677-692	16
α-helix	701-727	27
α-helix	731-733	3
α-helix	739-754	16
α-helix	755-757	3

Chain 03: 44 helices, 0 β-strands

Element	Residues	Length
α-helix	5-17	13
α-helix	22-37	16
α-helix	42-53	12
α-helix	60-71	12
α-helix	76-89	14
α-helix	94-104	11
α-helix	112-122	11
α-helix	129-139	11
α-helix	143-158	16
α-helix	167-177	11
α-helix	181-191	11
α-helix	195-198	4
α-helix	201-215	15
α-helix	224-249	26
α-helix	252-269	18
α-helix	277-303	27
α-helix	309-325	17
α-helix	327-329	3
α-helix	331-333	3
α-helix	340-341	2
α-helix	342-361	20
α-helix	368-376	9
α-helix	379-389	11
α-helix	412-415	4
α-helix	416-429	14
α-helix	434-444	11
α-helix	450-451	2
α-helix	453-460	8
α-helix	476-478	3
α-helix	481-503	23
α-helix	526-539	14
α-helix	547-562	16
α-helix	572-586	15
α-helix	592-616	25
α-helix	623-625	3
α-helix	637-639	3
α-helix	645-647	3
α-helix	649-661	13
α-helix	664-674	11
α-helix	677-692	16
α-helix	701-727	27
α-helix	731-733	3
α-helix	739-754	16
α-helix	755-757	3

Chain 04: 44 helices, 0 β-strands

Element	Residues	Length
α-helix	5-17	13
α-helix	22-26	5
α-helix	29-37	9
α-helix	42-53	12
α-helix	60-71	12
α-helix	76-89	14
α-helix	94-105	12
α-helix	112-122	11
α-helix	129-140	12
α-helix	143-158	16
α-helix	166-177	12
α-helix	181-191	11
α-helix	195-198	4
α-helix	201-215	15
α-helix	224-249	26
α-helix	252-269	18
α-helix	277-303	27
α-helix	309-325	17
α-helix	327-329	3
α-helix	340-341	2
α-helix	342-362	21
α-helix	368-376	9
α-helix	379-389	11
α-helix	412-415	4
α-helix	416-429	14
α-helix	434-444	11
α-helix	450-451	2
α-helix	453-460	8
α-helix	476-478	3
α-helix	481-503	23
α-helix	526-539	14
α-helix	547-562	16
α-helix	572-586	15
α-helix	592-616	25
α-helix	623-625	3
α-helix	637-639	3
α-helix	645-647	3
α-helix	649-661	13
α-helix	664-674	11
α-helix	677-692	16
α-helix	701-727	27
α-helix	731-733	3
α-helix	739-754	16
α-helix	755-757	3

Chain 10: 49 helices, 170 β-strands

Element	Residues	Length	Sheet
α-helix	7-10	4
α-helix	12-16	5
β-strand	28	1	115
β-strand	32-36	5	116
β-strand	44-48	5	117
β-strand	49	1	115
β-strand	54-58	5	116
β-strand	64-68	5	117
β-strand	77	1	116
β-strand	79-84	6	117
β-strand	92-100	9	116
β-strand	106-114	9	116
β-strand	118-122	5	118
β-strand	127-129	3	119
α-helix	132-134	3
β-strand	135-142	8	118
α-helix	147	1
β-strand	148	1	118
α-helix	149	1
β-strand	157-162	6	119
α-helix	173-175	3
β-strand	177-180	4	118
α-helix	182-184	3
α-helix	191-196	6
β-strand	202	1	119
β-strand	205-210	6	118
β-strand	214-222	9	119
α-helix	227-229	3
α-helix	231-232	2
β-strand	233-240	8	119
β-strand	242-246	5	120
β-strand	251-253	3	121
β-strand	258-260	3	122
β-strand	262-267	6	120
β-strand	270-273	4	120
β-strand	281-290	10	121
β-strand	301-303	3	122
β-strand	309-312	4	122
β-strand	316-324	9	121
β-strand	337-342	6	121
β-strand	345-353	9	123
β-strand	359-361	3	124
β-strand	365-374	10	123
α-helix	378	1
β-strand	379	1	123
α-helix	380-381	2
β-strand	386-391	6	124
β-strand	397-402	6	123
β-strand	408-413	6	123
β-strand	417-429	13	124
β-strand	435-451	17	124
β-strand	455-457	3	125
β-strand	460-464	5	126
β-strand	473-475	3	127
β-strand	477-479	3	125
β-strand	485-489	5	126
β-strand	495-497	3	127
β-strand	502-505	4	127
β-strand	510-518	9	126
β-strand	525-533	9	126
β-strand	535-540	6	128
α-helix	541	1
β-strand	546-548	3	129
β-strand	552-562	11	128
β-strand	570-572	3	128
β-strand	582-585	4	129
β-strand	591-594	4	128
α-helix	598-600	3
β-strand	606-612	7	128
β-strand	616-626	11	129
β-strand	629-640	12	129
β-strand	644-647	4	130
β-strand	651-654	4	131
β-strand	659-665	7	130
α-helix	675-677	3
β-strand	678-684	7	131
β-strand	690-694	5	130
α-helix	695-697	3
β-strand	705-712	8	130
β-strand	716-726	11	131
β-strand	737-746	10	131
β-strand	751-756	6	132
α-helix	758-761	4
α-helix	768-771	4
β-strand	776-780	5	133
β-strand	786-792	7	132
α-helix	797	1
β-strand	798	1	132
α-helix	799	1
β-strand	801	1	131
β-strand	805-811	7	133
β-strand	817-818	2	134
β-strand	826-831	6	132
β-strand	837-844	8	132
β-strand	846-847	2	134
β-strand	852-863	12	133
α-helix	865-871	7
α-helix	878-882	5
β-strand	883-892	10	133
α-helix	893-895	3
β-strand	896-898	3	135
β-strand	901-905	5	136
β-strand	912-917	6	135
β-strand	923-927	5	136
β-strand	933-938	6	135
α-helix	939-941	3
β-strand	943-948	6	135
β-strand	952-960	9	136
β-strand	969-976	8	136
β-strand	980-984	5	137
β-strand	988-990	3	138
β-strand	994-1002	9	137
α-helix	1007	1
β-strand	1008	1	137
α-helix	1009-1010	2
α-helix	1011-1017	7
β-strand	1020-1023	4	138
β-strand	1028-1033	6	137
β-strand	1042-1048	7	137
β-strand	1052-1061	10	138
β-strand	1067-1069	3	138
β-strand	1073-1078	6	138
α-helix	1079-1081	3
β-strand	1082-1084	3	139
β-strand	1087-1090	4	140
β-strand	1095-1097	3	141
β-strand	1099-1101	3	139
β-strand	1110-1114	5	140
β-strand	1120-1122	3	141
β-strand	1127-1130	4	141
β-strand	1134-1145	12	140
β-strand	1152-1164	13	140
β-strand	1167	1	142
β-strand	1171-1173	3	143
β-strand	1178-1180	3	144
β-strand	1184-1190	7	143
α-helix	1198-1200	3
β-strand	1208-1214	7	144
β-strand	1220-1224	5	143
α-helix	1227-1229	3
β-strand	1231	1	145
β-strand	1240-1245	6	143
β-strand	1249-1259	11	144
β-strand	1267	1	142
β-strand	1273-1283	11	144
α-helix	1284-1286	3
β-strand	1288-1290	3	146
β-strand	1292-1293	2	146
β-strand	1295	1	147
β-strand	1297-1300	4	148
β-strand	1305-1307	3	149
β-strand	1309-1310	2	150
β-strand	1313	1	151
β-strand	1316	1	151
β-strand	1317-1322	6	148
α-helix	1329-1330	2
β-strand	1332-1334	3	149
β-strand	1339-1342	4	149
β-strand	1347-1357	11	148
β-strand	1361-1371	11	148
β-strand	1376-1382	7	152
α-helix	1384-1385	2
β-strand	1386-1387	2	153
α-helix	1391-1392	2
β-strand	1393	1	145
β-strand	1396-1397	2	154
β-strand	1401-1409	9	152
α-helix	1414	1
β-strand	1415	1	152
α-helix	1416	1
β-strand	1418	1	148
β-strand	1423-1427	5	154
β-strand	1433-1437	5	152
β-strand	1443-1448	6	152
β-strand	1452-1460	9	154
β-strand	1467-1475	9	154
β-strand	1479	1	155
β-strand	1486-1487	2	156
β-strand	1491-1493	3	157
β-strand	1495	1	155
β-strand	1498-1499	2	153
β-strand	1507-1510	4	156
β-strand	1516-1518	3	157
β-strand	1524-1527	4	157
β-strand	1531-1539	9	156
β-strand	1543-1552	10	156
β-strand	1556-1561	6	158
α-helix	1563-1565	3
α-helix	1574-1576	3
β-strand	1577-1581	5	158
β-strand	1588-1589	2	157
α-helix	1594-1601	8
α-helix	1605-1608	4
β-strand	1609-1616	8	159
β-strand	1628-1629	2	160
β-strand	1632-1635	4	158
β-strand	1640-1643	4	158
β-strand	1646-1647	2	160
α-helix	1652-1660	9
β-strand	1664-1671	8	159
β-strand	1679-1681	3	158
α-helix	1682	1
β-strand	1683-1685	3	159
α-helix	1686	1
β-strand	1692-1693	2	161
β-strand	1698-1701	4	162
β-strand	1704	1	162
β-strand	1706-1712	7	161
α-helix	1715-1719	5
β-strand	1722-1725	4	162
β-strand	1730-1738	9	161
α-helix	1743	1
β-strand	1744-1751	8	161
α-helix	1756-1758	3
β-strand	1762-1770	9	162
β-strand	1775-1784	10	162
α-helix	1797-1800	4
α-helix	1802-1805	4
α-helix	1807-1828	22

Chain 11: 47 helices, 172 β-strands

Element	Residues	Length	Sheet
α-helix	7-10	4
α-helix	12-16	5
β-strand	28	1	197
β-strand	32-36	5	198
β-strand	44-48	5	199
β-strand	49	1	197
β-strand	54-58	5	198
β-strand	64-68	5	199
β-strand	77	1	198
β-strand	79-84	6	199
β-strand	92-100	9	198
β-strand	106-114	9	198
β-strand	118-122	5	200
β-strand	127-129	3	201
α-helix	132-134	3
β-strand	135-142	8	200
α-helix	147	1
β-strand	148	1	200
α-helix	149	1
β-strand	157-162	6	201
α-helix	173-175	3
β-strand	177-180	4	200
α-helix	182-184	3
α-helix	191-196	6
β-strand	202	1	201
β-strand	205-210	6	200
β-strand	214-222	9	201
α-helix	227-229	3
α-helix	231-232	2
β-strand	233-240	8	201
β-strand	242-246	5	202
β-strand	251-254	4	203
β-strand	258-260	3	204
β-strand	262-267	6	202
β-strand	270-273	4	202
β-strand	281-290	10	203
β-strand	301-303	3	204
β-strand	309-312	4	204
β-strand	316-324	9	203
β-strand	337-343	7	203
β-strand	345-353	9	205
β-strand	359-361	3	206
β-strand	365-374	10	205
α-helix	378	1
β-strand	379	1	205
β-strand	380	1	203
α-helix	381	1
β-strand	386-391	6	206
β-strand	397-402	6	205
β-strand	408-413	6	205
β-strand	417-429	13	206
β-strand	435-451	17	206
β-strand	455-457	3	207
β-strand	460-464	5	208
β-strand	473-475	3	209
β-strand	477-479	3	207
β-strand	485-489	5	208
β-strand	495-497	3	209
β-strand	502-505	4	209
β-strand	510-518	9	208
β-strand	525-533	9	208
β-strand	535-540	6	210
α-helix	541	1
β-strand	546-548	3	211
β-strand	552-562	11	210
β-strand	570-572	3	210
β-strand	582-585	4	211
β-strand	591-594	4	210
α-helix	598-600	3
β-strand	606-612	7	210
β-strand	616-626	11	211
β-strand	629-640	12	211
β-strand	644-647	4	212
β-strand	654	1	213
β-strand	659-665	7	212
α-helix	675-677	3
β-strand	678-683	6	214
β-strand	690-695	6	212
α-helix	696-697	2
β-strand	705-712	8	212
β-strand	720-726	7	214
β-strand	737-742	6	214
β-strand	751-756	6	215
α-helix	758-761	4
α-helix	768-771	4
β-strand	776-780	5	216
β-strand	786-792	7	215
α-helix	797	1
β-strand	798	1	215
α-helix	799	1
β-strand	801	1	213
β-strand	805-811	7	216
β-strand	817-818	2	217
β-strand	826-831	6	215
β-strand	837-844	8	215
β-strand	846-847	2	217
β-strand	852-863	12	216
α-helix	865-871	7
α-helix	878-882	5
β-strand	883-892	10	216
α-helix	893-895	3
β-strand	896-898	3	218
β-strand	901-905	5	219
β-strand	912-917	6	218
β-strand	923-927	5	219
β-strand	933-938	6	218
α-helix	939-941	3
β-strand	943-948	6	218
β-strand	952-960	9	219
β-strand	969-976	8	219
β-strand	980-984	5	220
β-strand	988-990	3	221
β-strand	994-1002	9	220
α-helix	1007	1
β-strand	1008	1	220
α-helix	1009-1010	2
α-helix	1011-1017	7
β-strand	1020-1023	4	221
β-strand	1028-1033	6	220
β-strand	1042-1048	7	220
β-strand	1052-1061	10	221
β-strand	1067-1069	3	221
β-strand	1073-1078	6	221
α-helix	1079-1081	3
β-strand	1082-1084	3	222
β-strand	1087-1091	5	223
β-strand	1095-1097	3	224
β-strand	1099-1101	3	222
β-strand	1107	1	144
β-strand	1110-1114	5	223
β-strand	1120-1122	3	224
β-strand	1127-1130	4	224
β-strand	1134-1145	12	223
β-strand	1152-1165	14	223
β-strand	1167	1	225
β-strand	1171-1173	3	226
β-strand	1178-1180	3	227
β-strand	1184-1190	7	226
α-helix	1198-1200	3
β-strand	1208-1214	7	227
β-strand	1220-1224	5	226
α-helix	1227-1229	3
β-strand	1231	1	228
β-strand	1240-1245	6	226
β-strand	1249-1259	11	227
β-strand	1267	1	225
β-strand	1273-1283	11	227
α-helix	1284-1286	3
β-strand	1288-1290	3	229
β-strand	1292-1293	2	229
β-strand	1295	1	230
β-strand	1297-1300	4	231
β-strand	1305-1307	3	232
β-strand	1309-1310	2	233
β-strand	1313	1	234
β-strand	1316	1	234
β-strand	1317-1322	6	231
β-strand	1332-1334	3	232
β-strand	1339-1342	4	232
β-strand	1347-1357	11	231
β-strand	1361-1371	11	231
β-strand	1376-1382	7	235
α-helix	1384-1385	2
β-strand	1386-1387	2	236
α-helix	1391-1392	2
β-strand	1393	1	228
β-strand	1396-1397	2	237
β-strand	1401-1409	9	235
α-helix	1414	1
β-strand	1415	1	235
α-helix	1416	1
β-strand	1418	1	231
β-strand	1423-1427	5	237
β-strand	1433-1437	5	235
β-strand	1443-1448	6	235
β-strand	1452-1460	9	237
β-strand	1467-1475	9	237
β-strand	1479	1	238
β-strand	1486-1487	2	239
β-strand	1491-1493	3	240
β-strand	1495	1	238
β-strand	1498-1499	2	236
β-strand	1507-1510	4	239
β-strand	1516-1518	3	240
β-strand	1524-1527	4	240
β-strand	1531-1539	9	239
β-strand	1543-1552	10	239
α-helix	1553-1554	2
β-strand	1556-1561	6	241
α-helix	1563-1565	3
α-helix	1574-1576	3
β-strand	1577-1581	5	241
β-strand	1588-1589	2	240
α-helix	1594-1601	8
α-helix	1605-1608	4
β-strand	1609-1616	8	242
β-strand	1628-1629	2	243
β-strand	1632-1635	4	241
β-strand	1640-1643	4	241
β-strand	1646-1647	2	243
α-helix	1652-1660	9
β-strand	1664-1671	8	242
β-strand	1679-1681	3	241
β-strand	1683-1685	3	242
β-strand	1692-1693	2	244
β-strand	1698-1701	4	245
β-strand	1704	1	245
β-strand	1706-1712	7	244
α-helix	1715-1719	5
β-strand	1722-1725	4	245
β-strand	1730-1738	9	244
α-helix	1743	1
β-strand	1744-1751	8	244
α-helix	1754-1758	5
β-strand	1762-1770	9	245
β-strand	1775-1784	10	245
α-helix	1797-1800	4
α-helix	1802-1805	4
α-helix	1807-1828	22

Chain 12: 50 helices, 171 β-strands

Element	Residues	Length	Sheet
α-helix	7-10	4
α-helix	12-16	5
β-strand	28	1	272
β-strand	32-36	5	273
β-strand	44-48	5	274
β-strand	49	1	272
β-strand	54-58	5	273
β-strand	64-68	5	274
β-strand	77	1	273
β-strand	79-84	6	274
β-strand	92-100	9	273
β-strand	106-114	9	273
β-strand	118-122	5	275
β-strand	127-129	3	276
α-helix	132-134	3
β-strand	135-142	8	275
α-helix	147	1
β-strand	148	1	275
α-helix	149	1
β-strand	157-162	6	276
α-helix	173-175	3
β-strand	177-180	4	275
α-helix	182-184	3
α-helix	191-196	6
β-strand	202	1	276
β-strand	205-210	6	275
β-strand	214-222	9	276
α-helix	227-229	3
α-helix	231-232	2
β-strand	233-240	8	276
β-strand	242-246	5	277
β-strand	251-253	3	278
β-strand	258-260	3	279
α-helix	261	1
β-strand	262-267	6	277
β-strand	270-273	4	277
β-strand	281-290	10	278
β-strand	301-303	3	279
β-strand	309-312	4	279
β-strand	316-324	9	278
β-strand	337-342	6	278
β-strand	345-353	9	280
β-strand	359-361	3	281
β-strand	365-374	10	280
α-helix	378	1
β-strand	379	1	280
β-strand	380	1	278
α-helix	381	1
β-strand	386-391	6	281
β-strand	397-402	6	280
β-strand	408-413	6	280
β-strand	417-429	13	281
β-strand	435-451	17	281
β-strand	455-457	3	282
β-strand	460-464	5	283
β-strand	473-475	3	284
α-helix	476	1
β-strand	477-479	3	282
β-strand	485-489	5	283
β-strand	495-497	3	284
β-strand	502-505	4	284
β-strand	510-518	9	283
β-strand	525-533	9	283
β-strand	535-540	6	285
α-helix	541	1
β-strand	546-548	3	286
β-strand	552-562	11	285
β-strand	570-572	3	285
β-strand	582-585	4	286
β-strand	591-594	4	285
α-helix	598-600	3
β-strand	606-612	7	285
β-strand	616-626	11	286
β-strand	629-640	12	286
β-strand	644-647	4	287
β-strand	651-654	4	288
β-strand	659-665	7	287
α-helix	675-677	3
β-strand	678-684	7	288
β-strand	690-695	6	287
α-helix	696-697	2
β-strand	705-712	8	287
β-strand	716-726	11	288
β-strand	737-746	10	288
β-strand	751-756	6	289
α-helix	758-761	4
α-helix	768-771	4
β-strand	776-780	5	290
β-strand	786-792	7	289
α-helix	797	1
β-strand	798	1	289
α-helix	799	1
β-strand	801	1	288
β-strand	805-811	7	290
β-strand	817-818	2	291
β-strand	826-831	6	289
β-strand	837-844	8	289
β-strand	846-847	2	291
β-strand	852-863	12	290
α-helix	865-868	4
α-helix	878-882	5
β-strand	883-892	10	290
α-helix	893-895	3
β-strand	896-898	3	292
β-strand	901-905	5	293
β-strand	912-917	6	292
β-strand	923-927	5	293
β-strand	933-938	6	292
α-helix	939-941	3
β-strand	943-948	6	292
β-strand	952-960	9	293
β-strand	969-976	8	293
β-strand	980-984	5	294
β-strand	988-990	3	295
β-strand	994-1002	9	294
α-helix	1007	1
β-strand	1008	1	294
α-helix	1009-1010	2
α-helix	1011-1017	7
β-strand	1020-1023	4	295
β-strand	1028-1033	6	294
β-strand	1042-1048	7	294
β-strand	1052-1061	10	295
β-strand	1067-1069	3	295
β-strand	1073-1078	6	295
α-helix	1079-1081	3
β-strand	1082-1084	3	296
β-strand	1087-1091	5	297
β-strand	1095-1097	3	298
β-strand	1099-1101	3	296
β-strand	1110-1114	5	297
β-strand	1120-1122	3	298
β-strand	1127-1130	4	298
β-strand	1134-1145	12	297
β-strand	1152-1165	14	297
β-strand	1167	1	299
β-strand	1171-1173	3	300
β-strand	1178-1180	3	301
β-strand	1184-1190	7	300
α-helix	1194-1196	3
α-helix	1198-1200	3
β-strand	1208-1214	7	301
β-strand	1220-1224	5	300
α-helix	1227-1229	3
β-strand	1231	1	302
β-strand	1240-1245	6	300
β-strand	1249-1259	11	301
β-strand	1267	1	299
β-strand	1273-1283	11	301
α-helix	1284-1286	3
β-strand	1288-1290	3	303
β-strand	1292-1293	2	303
β-strand	1295	1	304
β-strand	1297-1300	4	305
β-strand	1305-1307	3	306
β-strand	1309-1310	2	307
β-strand	1313	1	308
β-strand	1316	1	308
β-strand	1317-1322	6	305
β-strand	1332-1334	3	306
β-strand	1339-1342	4	306
β-strand	1347-1357	11	305
β-strand	1361-1371	11	305
β-strand	1376-1382	7	309
α-helix	1384-1385	2
β-strand	1386-1387	2	310
α-helix	1391-1392	2
β-strand	1393	1	302
β-strand	1396-1397	2	311
β-strand	1401-1409	9	309
α-helix	1414	1
β-strand	1415	1	309
α-helix	1416	1
β-strand	1418	1	305
β-strand	1423-1427	5	311
β-strand	1433-1437	5	309
β-strand	1443-1448	6	309
β-strand	1452-1460	9	311
β-strand	1467-1475	9	311
β-strand	1479	1	312
β-strand	1486-1487	2	313
β-strand	1491-1493	3	314
β-strand	1495	1	312
β-strand	1498-1499	2	310
β-strand	1507-1510	4	313
β-strand	1516-1518	3	314
β-strand	1524-1527	4	314
β-strand	1531-1539	9	313
β-strand	1543-1552	10	313
β-strand	1556-1561	6	315
α-helix	1563-1565	3
α-helix	1574-1576	3
β-strand	1577-1581	5	315
β-strand	1588-1589	2	314
α-helix	1594-1602	9
α-helix	1605-1608	4
β-strand	1609-1616	8	316
β-strand	1628-1629	2	317
β-strand	1632-1635	4	315
β-strand	1640-1643	4	315
β-strand	1646-1647	2	317
α-helix	1648	1
α-helix	1652-1660	9
β-strand	1664-1671	8	316
β-strand	1679-1681	3	315
α-helix	1682	1
β-strand	1683-1685	3	316
β-strand	1692-1693	2	318
β-strand	1698-1701	4	319
β-strand	1704	1	319
β-strand	1706-1712	7	318
α-helix	1715-1719	5
β-strand	1722-1725	4	319
β-strand	1730-1738	9	318
α-helix	1743	1
β-strand	1744-1751	8	318
α-helix	1756-1758	3
β-strand	1762-1770	9	319
β-strand	1775-1784	10	319
α-helix	1802-1805	4
α-helix	1807-1828	22

76 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
E3 SUMO-protein ligase RanBP2	00, 01, 02, 03, 04	protein	3224	Homo sapiens	P49792
Nuclear pore membrane glycoprotein 210	10, 11, 12, 13, 14, 15, 16, 17	protein	1887	Homo sapiens	Q8TEM1 (AlphaFold model)
Aladin	40, 41	protein	546	Homo sapiens	Q9NRG9 (AlphaFold model)
Nuclear pore complex protein Nup93	A0, A1, A2, A3, A4, A5, A6	protein	819	Homo sapiens	Q8N1F7 (AlphaFold model)
Nucleoporin NUP188 homolog	B0, B1	protein	1749	Homo sapiens	Q5SRE5
Nuclear pore complex protein Nup205	C0, C1, C2, C3, C4	protein	2012	Homo sapiens	Q92621
Nuclear pore complex protein Nup155	D0, D1, D2, D3, D4, D5	protein	1391	Homo sapiens	O75694
Nucleoporin NDC1	E0, E1	protein	674	Homo sapiens	Q9BTX1
Nucleoporin NUP35	F0, F1, F2, F3	protein	326	Homo sapiens	Q8NFH5
Nucleoporin p54	H0, H1, H2, H3	protein	507	Homo sapiens	Q7Z3B4
Nucleoporin p58/p45	I0, I1, I2, I3	protein	599	Homo sapiens	Q9BVL2
Nuclear pore glycoprotein p62	J0, J1, J2, J3, J4	protein	522	Homo sapiens	P37198

13 more molecules are not listed.

Sequence of entity 1 (00, 01, 02, 03, 04), FASTA

>7R5K_1 E3 SUMO-protein ligase RanBP2 (chains 00, 01, 02, 03, 04)
MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP
KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER
AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR
LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA
NLMLLTLSTRDVQESRELLQSFDSALQSVKSLGGNDELSATFLEMKGHFYMHAGSLLLKM
GQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLLN
LSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDLT
RYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESIC
ILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLIH
RKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYIG
RSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAV
NGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLIK
IIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTP
SPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPHR
WPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKG
PVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGDD
YFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSLP
TQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGDG
YSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGKS
VFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAK
LFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGS
DRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQAV
RIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLNP
SNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQN
TKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCA
ACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANA
TRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE
ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA
SATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEAS
ATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLK
CVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFK
FGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGT
GFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLFS
SQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRV
KLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSG
SDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDT
GRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTGP
TLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSKS
PAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKLY
RYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTER
VWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPR
ESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSES
VKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELS
KNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELTP
TAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPLE
ENTADNEKECIIVWEKKPTVEEKAKADTLKLPPTFFCGVCSDTDEDNGNGEDFQSELQKV
QEAQKSQTEEITSTTDSVYTGGTEVMVPSFCKSEEPDSITKSISSPSVSSETMDKPVDLS
TRKEIDTDSTSQGESKIVSFGFGSSTGLSFADLASSNSGDFAFGSKDKNFQWANTGAAVF
GTQSVGTQSAGKVGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKL
YRWDRDVSQWKERGVGDIKILWHTMKNYYRILMRRDQVFKVCANHVITKTMELKPLNVSN
NALVWTASDYADGEAKVEQLAVRFKTKEVADCFKKTFEECQQNLMKLQKGHVSLAAELSK
ETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDF
VCQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQGQNTNNSQFVITLKKAE
HLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITECGQI

Sequence of entity 2 (10, 11, 12, 13, 14, 15, 16, 17), FASTA

>7R5K_2 Nuclear pore membrane glycoprotein 210 (chains 10, 11, 12, 13, 14, 15, 16, 17)
MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTR
PEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQ
IVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRIL
TFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLIL
ENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPV
AVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVL
ETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTA
IDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHG
GSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEF
APCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPP
GSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSK
EMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVI
ALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVS
SHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLH
GLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPE
EVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHD
LCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLK
LRAASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPP
FRLMPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSG
LVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFS
FGNAVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAV
DPTSGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSY
RVLDGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVS
MSPVLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPT
NNTCVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTS
LEGLSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMAR
HLHPIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVF
DFPSQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQ
VGAEVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFG
WPSFITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLF
QHFLDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASS
PTSPNALPPARKASPPSGLWSPAYASH

Sequence of entity 3 (40, 41), FASTA

>7R5K_3 Aladin (chains 40, 41)
MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGR
LDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRW
ASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNA
SSTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLS
HPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGS
KILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPE
RCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPR
VQDGKPVILLFRTRNSPVFELLPCGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIA
HIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPH
SPHSHL

Sequence of entity 4 (A0, A1, A2, A3, A4, A5, A6), FASTA

>7R5K_4 Nuclear pore complex protein Nup93 (chains A0, A1, A2, A3, A4, A5, A6)
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKA
SVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKR
TFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDN
IEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKSISDMWTMVKQMTDVLLTPATD
ALKNRSSVEVRMEFVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIK
LPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKD
RRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQ
VCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAVAFLF
RMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCLRRLNFVRLLMLYTRKFE
STDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDK
FTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNK
ERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLV
PLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSSRPQRVIED
RDSQLRSQARTLITFAGMIPYRTSGDTNARLVQMEVLMN

Sequence of entity 5 (B0, B1), FASTA

>7R5K_5 Nucleoporin NUP188 homolog (chains B0, B1)
MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKHWRRLLEGLSYYKPPSPSSAEK
VKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDSVKTVLQDERQSQA
LILKIADYYYEERTCILRCVLHLLTYFQDERHPYRVEYADCVDKLEKELVSKYRQQFEEL
YKTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVLTKMFK
EQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDG
LICQDMDCLMLTFGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTR
LLQSLASGGNDCTTSTACMCVYGLLSFVLTSLELHTLGNQQDIIDTACEVLADPSLPELF
WGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELYKH
KPHDVISHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWT
LFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRL
TTVISPPVDVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSSLSQMISAEGMNA
GGYGNLLMNSEQPQGEYGVTIAFLRLITTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHK
WRYNSHGVREQIGCLILELIHAILNLCHETDLHSSHTPSLQFLCICSLAYTEAGQTVINI
MGIGVDTIDMVMAAQPRSDGAEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQA
LSQHGAHGNNLIAVLAKYIYHKHDPALPRLAIQLLKRLATVAPMSVYACLGNDAAAIRDA
FLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGMWSCLH
AVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGT
LSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSIEKRFAYWSGYVK
SLAVHVAETEGSSCTSLLEYQMLVSAWRMLLIIATTHADIMHLTDSVVRRQLFLDVLDGT
KALLLVPASVNCLRLGSMKCTLLLILLRQWKRELGSVDEILGPLTEILEGVLQADQQLME
KTKAKVFSAFITVLQMKEMKVSDIPQYSQLVLNVCETLQEEVIALFDQTRHSLALGSATE
DKDSMETDDCSRSRHRDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTL
EVSLRMKQNLHFTEATLHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSTNGTAQT
PSASRKSLDAPSWPGVYRLSMSLMEQLLKTLRYNFLPEALDFVGVHQERTLQCLNAVRTV
QSLACLEEADHTVGFILQLSNFMKEWHFHLPQLMRDIQVNLGYLCQACTSLLHSRKMLQH
YLQNKNGDGLPSAVAQRVQRPPSAASAAPSSSKQPAADTEASEQQALHTVQYGLLKILSK
TLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNM
LGELDKKKEPLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAMRYLRDPAVHPRDK
QRMKQELSSELSTLLSSLSRYFRRGAPSSPATGVLPSPQGKSTSLSKASPESQEPLIQLV
QAFVRHMQR

Sequence of entity 6 (C0, C1, C2, C3, C4), FASTA

>7R5K_6 Nuclear pore complex protein Nup205 (chains C0, C1, C2, C3, C4)
MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKN
VQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQP
HFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQ
GLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSP
LGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPL
LTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMA
ELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARM
IHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYL
GVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSS
HVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAF
LQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIA
ASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFP
SNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQL
EDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKK
HLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIA
RYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDA
EEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNL
QDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPT
MRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLL
HLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQ
LDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEIS
TVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHD
KILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPP
EENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDT
LEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALL
DRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFL
TRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQIL
LPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGII
SKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEG
DKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQ
APVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMP
AGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDS
QDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLL
DIEGLYSKVRSRYSFIQALVRRIRGLLRISRN

Sequence of entity 7 (D0, D1, D2, D3, D4, D5), FASTA

>7R5K_7 Nuclear pore complex protein Nup155 (chains D0, D1, D2, D3, D4, D5)
MPSSLLGAAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGM
SDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTID
SDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSY
ANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAY
QAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGVI
QVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLA
VTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLM
AASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDH
IPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFK
LHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILGS
PVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYS
GKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEF
LDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQA
IQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIAS
LINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRES
LKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIV
GLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHF
EQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDL
LWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEF
LHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAE
CKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPR
FFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKP
LHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNF
KSLQAKLERLH

Sequence of entity 8 (E0, E1), FASTA

>7R5K_8 Nucleoporin NDC1 (chains E0, E1)
MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSD
SFSDLYSSYVIFYFLLLSVVIIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFI
HAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSY
SLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHV
FPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPH
NWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQM
PRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIM
YFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQE
AVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASA
EHQKRLQQFLEFKE

Sequence of entity 9 (F0, F1, F2, F3), FASTA

>7R5K_9 Nucleoporin NUP35 (chains F0, F1, F2, F3)
MAAFAVEPQGPALGSEPMMLGSPTSPKPGVNAQFLPGFLMGDLPAPVTPQPRSISGPSVG
VMEMRSPLLAGGSPPQPVVPAHKDKSGAPPVRSIYDDISSPGLGSTPLTSRRQPNISVMQ
SPLVGVTSTPGTGQSMFSPASIGQPRKTTLSPAQLDPFYTQGDSLTSEDHLDDSWVTVFG
FPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGV
KPCIDKSVMESSDRCALSSPSLAFTPPIKTLGTPTQPGSTPRISTMRPLATAYKASTSDY
QVISDRQTPKKDESLVSKAMEYMFGW

Sequence of entity 10 (H0, H1, H2, H3), FASTA

>7R5K_10 Nucleoporin p54 (chains H0, H1, H2, H3)
MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG
FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT
ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC
MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV
VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP
PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE
LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE
LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI
IKDDLEDIKLVEHGLNETIHIRGGVFS

Sequence of entity 11 (I0, I1, I2, I3), FASTA

>7R5K_11 Nucleoporin p58/p45 (chains I0, I1, I2, I3)
MSTGFSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATTSAPS
SGFGTGLFGSKPATGFTLGGTNTGIATTITTGLTLGTPATTSAATTGFSLGFNKPAASAT
PFALPITSTSASGLTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLGGALAGLGG
SLFQSTNTGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDKKSDKTGTRPEDSK
ALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAANG
IQRNTLNIDKLKIETAQELKNAEIALRTQKTPPGLQHEYAAPADYFRILVQQFEVQLQQY
RQQIEELENHLATQANNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLKEQYLGY
RKMFLGDAVDVFETRRAEAKKWQNTPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGP
QPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCSTTGASTFGFGTTNKPSGS
LSAGFGSSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGGQLLQLKKPPAGNKRGKR

Sequence of entity 12 (J0, J1, J2, J3, J4), FASTA

>7R5K_12 Nuclear pore glycoprotein p62 (chains J0, J1, J2, J3, J4)
MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLF
SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN
LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA
QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC
TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPA
GIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNA
WDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGT
IYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNA
HMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD

Primary citation

AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Mosalaganti, S., Obarska-Kosinska, A., Siggel, M. et al. Science (2022) 376:eabm9506-eabm9506. DOI 10.1126/science.abm9506 · PubMed

Other PDB entries of the same protein (UniProt P49792), best resolution first:

7MNK 1.1 Å, Crystal structure of the tetramerization element of NUP358/RanBP2 (residues 805-832)
4GA0 1.15 Å, Structure of the N-terminal domain of Nup358
4I9Y 1.75 Å, Structure of the C-terminal domain of Nup358
7MNR 1.8 Å, Crystal Structure of the ZnF3 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
7MNV 1.8 Å, Crystal Structure of the ZnF8 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
4LQW 1.95 Å, Crystal structure of HIV-1 capsid N-terminal domain in complex with NUP358 cyclophilin
7MNU 2.0 Å, Crystal Structure of the ZnF7 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
7MNP 2.05 Å, Crystal Structure of the ZnF2 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
7MNQ 2.05 Å, Crystal Structure of the ZnF2 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
7MNS 2.1 Å, Crystal Structure of the ZnF4 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
3UIP 2.29 Å, Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2…
7MNZ 2.35 Å, Crystal Structure of Nup358/RanBP2 Ran-binding domain 4 in complex with Ran-GPPNHP

Browse structure collections

About this viewer

MolViewer shows 7R5K directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.