Dynactin subunit 4 (DCTN4) is a 467-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: A0A4X1TB62.
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The mean pLDDT of this model is 82.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 56% |
| 70 to 90 | Confident: backbone generally right | 26% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:33734450, PubMed:36071160). Together with dynein is involved in spindle assembly and cytokinesis (By similarity)
Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3 (PubMed:33734450, PubMed:36071160). The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder…
Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, stress fiber, Cytoplasm, cell cortex, Cytoplasm, myofibril, sarcomere
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7Z8M | EM | 3.37 Å | Y=1-467 |
| 8PR4 | EM | 3.5 Å | Y=1-467 |
| 6ZNL | EM | 3.8 Å | Y=1-467 |
| 9DGS | EM | 3.9 Å | Y=1-467 |
| 9YNG | EM | 4.07 Å | Y=1-467 |
| 6ZNM | EM | 4.1 Å | Y=1-467 |
| 6ZNN | EM | 4.5 Å | Y=1-467 |
| 9HHL | EM | 6.53 Å | Y=1-467 |
| 6ZNO | EM | 6.8 Å | Y=1-467 |
| 9DGU | EM | 7.1 Å | Y=1-467 |
| 9DGT | EM | 7.2 Å | Y=1-467 |
| 6ZO4 | EM | 8.2 Å | Y=1-467 |
| 9DGV | EM | 8.8 Å | Y=1-467 |
| 8PTK | EM | 10.0 Å | Y=1-467 |
| 9DGR | EM | 15.0 Å | Y=1-467 |
| 7Z8F | EM | 20.0 Å | Y=1-467 |
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