Transcriptional activator Myb (Myb) is a 636-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P06876.
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The mean pLDDT of this model is 58.5 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 24% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 57% |
What pLDDT means and how to read it
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells
Binds to HIPK1 (By similarity). Interacts with HIPK2, MAF, MYBBP1A and NLK
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1GVD | X-ray | 1.45 Å | A=90-141 |
| 1GV5 | X-ray | 1.58 Å | A=90-141 |
| 1GUU | X-ray | 1.6 Å | A=38-89 |
| 1GV2 | X-ray | 1.68 Å | A=89-193 |
| 6DNQ | X-ray | 2.35 Å | A/C=284-315 |
| 1H89 | X-ray | 2.45 Å | C=35-193 |
| 1H88 | X-ray | 2.8 Å | C=35-193 |
| 6DMX | X-ray | 2.8 Å | A/C/F/H=284-315 |
| 1IDY | NMR | A=141-193 | |
| 1IDZ | NMR | A=141-193 | |
| 1MBE | NMR | A=38-89 | |
| 1MBF | NMR | A=38-89 | |
| 1MBG | NMR | A=90-141 | |
| 1MBH | NMR | A=90-141 | |
| 1MBJ | NMR | A=142-193 | |
| 1MBK | NMR | A=142-193 | |
| 1MSE | NMR | C=90-193 | |
| 1MSF | NMR | C=90-193 | |
| 1SB0 | NMR | B=291-315 | |
| 2AGH | NMR | A=291-315 |
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