F-actin-capping protein subunit beta isoforms 1 and 2 (CAPZB) is a 277-residue protein from Gallus gallus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P14315.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 90.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 68% |
| 70 to 90 | Confident: backbone generally right | 26% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization
Component of the F-actin capping complex, composed of a heterodimer of an alpha and a beta subunit. Component of the WASH complex (By similarity)
Cytoplasm, myofibril, sarcomere, Z line, Cytoplasm, myofibril, sarcomere, I band, Cytoplasm, cytoskeleton
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7DS6 | X-ray | 1.69 Å | B=1-244 |
| 3AA0 | X-ray | 1.7 Å | B=1-244 |
| 7DS4 | X-ray | 1.85 Å | B=1-244 |
| 3AA1 | X-ray | 1.9 Å | B=1-244 |
| 3AA6 | X-ray | 1.9 Å | B=1-244 |
| 3AA7 | X-ray | 1.9 Å | B=1-244 |
| 7DS2 | X-ray | 1.95 Å | B=1-244 |
| 7DS8 | X-ray | 1.95 Å | B=1-244 |
| 3LK4 | X-ray | 1.99 Å | 2/5/8/B/E/H/K/N/Q/T/W/Z=1-277 |
| 9BLI | X-ray | 2.0 Å | B=1-244 |
| 7DS3 | X-ray | 2.09 Å | B=1-244 |
| 1IZN | X-ray | 2.1 Å | B/D=1-277 |
| 3AAA | X-ray | 2.2 Å | B=1-277 |
| 3LK2 | X-ray | 2.2 Å | B=1-243 |
| 7DSB | X-ray | 2.44 Å | B=1-244 |
| 3LK3 | X-ray | 2.68 Å | B=1-277 |
| 7DSA | X-ray | 2.8 Å | B=1-244 |
| 3AAE | X-ray | 3.3 Å | B/D/F/H/J=1-277 |
| 2KXP | NMR | B=2-271 | |
| 2KZ7 | NMR | B=1-277 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.