1QQP: Protein

Name: PDB 1QQP: Foot-and-mouth disease virus/ oligosaccharide receptor complex.
Published: 1999-06-18
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: virus

Foot-and-mouth disease virus/ oligosaccharide receptor complex. Determined by X-ray diffraction at 1.9 Å resolution. Released 18 Jun 1999.

Method: X-ray diffraction
Resolution: 1.9 Å
Organism: Foot-and-mouth disease virus
Chains: 4
Atoms: 6,002
Mol. weight: 82.27 kDa
Released: 18 Jun 1999

Explore 1QQP in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1QQP contains 28 α-helices and 39 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 1: 9 helices, 10 β-strands

Element	Residues	Length	Sheet
β-strand	11	1	1
α-helix	15-18	4
α-helix	28-30	3
α-helix	32-36	5
β-strand	39-42	4	2
α-helix	43-45	3
β-strand	49-50	2	3
α-helix	53-55	3
α-helix	61-67	7
β-strand	69-83	15	2
β-strand	86-89	4	3
α-helix	95-99	5
β-strand	105-106	2	3
α-helix	107-108	2
β-strand	113-117	5	2
β-strand	126-127	2	2
β-strand	167-169	3	3
β-strand	172-188	17	2
α-helix	204-206	3

Chain 2: 7 helices, 13 β-strands

Element	Residues	Length	Sheet
α-helix	11-13	3
β-strand	15-19	5	4
β-strand	22-26	5	4
β-strand	33-34	2	5
α-helix	35	1
α-helix	46-48	3
β-strand	53-54	2	5
α-helix	56-58	3
β-strand	62-69	8	5
β-strand	78-83	6	6
α-helix	90-97	8
β-strand	98-111	14	5
β-strand	118-127	10	6
α-helix	135-142	8
β-strand	145-148	4	6
β-strand	155-160	6	5
β-strand	169	1	5
β-strand	177-188	12	6
β-strand	197-213	17	5
α-helix	214-216	3

Chain 3: 8 helices, 15 β-strands

Element	Residues	Length	Sheet
β-strand	15	1	3
α-helix	22-24	3
α-helix	31-33	3
α-helix	44-50	7
β-strand	53-54	2	7
β-strand	57	1	8
β-strand	61	1	8
β-strand	63-65	3	7
β-strand	73-78	6	9
α-helix	84-86	3
α-helix	90-95	6
β-strand	98-102	5	10
β-strand	105-111	7	7
β-strand	118-126	9	9
α-helix	131-133	3
α-helix	136-139	4
β-strand	143-148	6	9
β-strand	154-159	6	7
α-helix	160-161	2
β-strand	168-169	2	10
β-strand	183-192	10	9
β-strand	198-205	8	7
β-strand	210-214	5	10

Chain 4: 4 helices, 1 β-strand

Element	Residues	Length	Sheet
α-helix	23-24	2
α-helix	28-31	4
α-helix	33-35	3
α-helix	67-73	7
β-strand	76	1	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Protein (genome polyprotein)	1	protein	213	Foot-and-mouth disease virus	P03305
Protein (genome polyprotein)	2	protein	218	Foot-and-mouth disease virus	P03305
Protein (genome polyprotein)	3	protein	220	Foot-and-mouth disease virus	P03305
Protein (genome polyprotein)	4	protein	85	Foot-and-mouth disease virus	P03305

Sequence of entity 1 (1), FASTA

>1QQP_1 PROTEIN (GENOME POLYPROTEIN) (chains 1)
TTSAGESADPVTTTVENYGGETQIQRRQHTDVSFIMDRFVKVTPQNQINILDLMQVPSHT
LVGALLRASTYYFSDLEIAVKHEGDLTWVPNGAPEKALDNTTNPTAYHKAPLTRLALPYT
APHRVLATVYNGECRYSRNAVPNLRGDLQVLAQKVARTLPTSFNYGAIKATRVTELLYRM
KRAETYCPRPLLAIHPTEARHKQKIVAPVKQTL

Sequence of entity 2 (2), FASTA

>1QQP_2 PROTEIN (GENOME POLYPROTEIN) (chains 2)
DKKTEETTLLEDRILTTRNGHTTSTTQSSVGVTYGYATAEDFVSGPNTSGLETRVVQAER
FFKTHLFDWVTSDSFGRCHLLELPTDHKGVYGSLTDSYAYMRNGWDVEVTAVGNQFNGGC
LLVAMVPELCSIQKRELYQLTLFPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLV
VMVVAPLTVNTEGAPQIKVYANIAPTNVHVAGEFPSKE

Sequence of entity 3 (3), FASTA

>1QQP_3 PROTEIN (GENOME POLYPROTEIN) (chains 3)
GIFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNQLPGRFTNLLDVAEACPTFLRFEGG
VPYVTTKTDSDRVLAQFDMSLAAKHMSNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKAR
YMVAYAPPGMEPPKTPEAAAHCIHAEWDTGLNSKFTFSIPYLSAADYTYTASDVAETTNV
QGWVCLFQITHGKADGDALVVLASAGKDFELRLPVDARAE

Sequence of entity 4 (4), FASTA

>1QQP_4 PROTEIN (GENOME POLYPROTEIN) (chains 4)
GAGQSSPATGSQNQSGNTGSIINNYYMQQYQNSMDTQLGNDAISGGSNEGSTDTTSTHTT
NTQNNDWFSKLASSAFSGLFGALLA

Primary citation

The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex. Fry, E.E., Lea, S.M., Jackson, T. et al. EMBO J (1999) 18:543-554. DOI 10.1093/emboj/18.3.543 · PubMed

Other PDB entries of the same protein (UniProt P03305), best resolution first:

6FFA 1.5 Å, FMDV Leader protease bound to substrate ISG15
4QBB 1.6 Å, Structure of the foot-and-mouth disease virus leader proteinase in complex with…
9HV9 1.8 Å, Crystal structure of Fab34 complexed with a 7-mer peptide of FMDV VP1
1QMY 1.9 Å, Fmdv leader protease (lbshort-C51A-C133S)
1QOL 3.0 Å, Structure of the fmdv leader protease
9HVA 3.89 Å, Crystal structure of Fab34 complexed with a 18-mer peptide of FMDV VP1
2JQF Full Length Leader Protease of Foot and Mouth Disease Virus C51A Mutant
2JQG Leader Protease

Browse structure collections

About this viewer

MolViewer shows 1QQP directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.