phosphorylated Crk-II. Determined by solution NMR. Released 8 May 2007.
Explore 2DVJ in 3D Show helices and sheets RCSB PDB PDBe
2DVJ contains 3 α-helices and 13 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 22-27 | 6 | |
| β-strand | 35 | 1 | 1 |
| β-strand | 36-38 | 3 | 2 |
| β-strand | 48-50 | 3 | 2 |
| β-strand | 60-61 | 2 | 2 |
| β-strand | 63 | 1 | 3 |
| β-strand | 87-88 | 2 | 3 |
| β-strand | 93-94 | 2 | 3 |
| α-helix | 97-101 | 5 | |
| β-strand | 117 | 1 | 1 |
| β-strand | 138 | 1 | 4 |
| β-strand | 158 | 1 | 4 |
| β-strand | 163 | 1 | 5 |
| β-strand | 169-173 | 5 | 5 |
| β-strand | 179-183 | 5 | 5 |
| α-helix | 184-186 | 3 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| V-crk sarcoma virus CT10 oncogene homolog, isoform a | A | protein | 230 | Homo sapiens | P46108 (AlphaFold model) |
>2DVJ_1 V-crk sarcoma virus CT10 oncogene homolog, isoform a (chains A) GAMAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVS HYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPV SRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGK RGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNT
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Kobashigawa, Y., Sakai, M., Naito, M. et al. Nat Struct Mol Biol (2007) 14:503-510. DOI 10.1038/nsmb1241 · PubMed
Other PDB entries of the same protein (UniProt P46108 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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