6PTJ: Ctf4 trimer
Structure of Ctf4 trimer in complex with one CMG helicase. Determined by electron microscopy at 3.8 Å resolution. Released 20 Nov 2019.
- Method
- Electron microscopy
- Resolution
- 3.8 Å
- Organisms
- Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
- Chains
- 14
- Atoms
- 34,361
- Mol. weight
- 1099.61 kDa
- Released
- 20 Nov 2019
Explore 6PTJ in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6PTJ contains 143 α-helices and 215 β-strands across 14 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 2: 9 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 204-211 | 8 | |
| α-helix | 213-216 | 4 | |
| β-strand | 241-244 | 4 | 15 |
| α-helix | 247-250 | 4 | |
| α-helix | 254-261 | 8 | |
| α-helix | 264-279 | 16 | |
| β-strand | 294-297 | 4 | 15 |
| α-helix | 311-313 | 3 | |
| β-strand | 320-327 | 8 | 16 |
| β-strand | 333 | 1 | 17 |
| β-strand | 337 | 1 | 18 |
| β-strand | 351 | 1 | 18 |
| β-strand | 383 | 1 | 17 |
| β-strand | 386-391 | 6 | 16 |
| α-helix | 397-398 | 2 | |
| α-helix | 401-403 | 3 | |
| β-strand | 405-410 | 6 | 16 |
| β-strand | 423-426 | 4 | 16 |
| β-strand | 429-431 | 3 | 16 |
| β-strand | 446 | 1 | 19 |
| β-strand | 450-452 | 3 | 16 |
| α-helix | 453 | 1 | |
| β-strand | 456-457 | 2 | 16 |
Chain 3: 6 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 19-26 | 8 | |
| α-helix | 37-51 | 15 | |
| α-helix | 53-56 | 4 | |
| β-strand | 96 | 1 | 20 |
| α-helix | 103-106 | 4 | |
| α-helix | 108-114 | 7 | |
| α-helix | 122-135 | 14 | |
| β-strand | 155 | 1 | 20 |
| β-strand | 179-186 | 8 | 21 |
| β-strand | 193-198 | 6 | 21 |
| β-strand | 201-202 | 2 | 22 |
| β-strand | 209 | 1 | 22 |
| β-strand | 213 | 1 | 21 |
| β-strand | 242-243 | 2 | 22 |
| β-strand | 249-259 | 11 | 21 |
| β-strand | 273-279 | 7 | 21 |
| β-strand | 291-297 | 7 | 21 |
| β-strand | 321-322 | 2 | 21 |
| β-strand | 327-328 | 2 | 21 |
Chain 4: 8 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 185-187 | 3 | |
| α-helix | 193-199 | 7 | |
| α-helix | 205-207 | 3 | |
| α-helix | 225-236 | 12 | |
| β-strand | 241 | 1 | 23 |
| α-helix | 255-263 | 9 | |
| α-helix | 267-278 | 12 | |
| α-helix | 281-284 | 4 | |
| β-strand | 303 | 1 | 23 |
| β-strand | 326-335 | 10 | 24 |
| β-strand | 339-342 | 4 | 25 |
| β-strand | 344-345 | 2 | 26 |
| β-strand | 348 | 1 | 27 |
| β-strand | 358-359 | 2 | 26 |
| β-strand | 383 | 1 | 27 |
| β-strand | 391-394 | 4 | 25 |
| β-strand | 395-401 | 7 | 24 |
| β-strand | 414-419 | 6 | 24 |
| α-helix | 421-423 | 3 | |
| β-strand | 433-437 | 5 | 24 |
| β-strand | 440-445 | 6 | 24 |
| β-strand | 453-461 | 9 | 24 |
| β-strand | 463-467 | 5 | 24 |
Chain 5: 7 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 29-37 | 9 | |
| α-helix | 45-47 | 3 | |
| α-helix | 52-55 | 4 | |
| β-strand | 60-64 | 5 | 28 |
| α-helix | 66-71 | 6 | |
| α-helix | 73-81 | 9 | |
| α-helix | 87-94 | 8 | |
| β-strand | 136-140 | 5 | 28 |
| α-helix | 145-147 | 3 | |
| β-strand | 159-166 | 8 | 29 |
| β-strand | 175-183 | 9 | 30 |
| β-strand | 190-193 | 4 | 30 |
| β-strand | 241-251 | 11 | 30 |
| β-strand | 258-259 | 2 | 29 |
| β-strand | 273-274 | 2 | 29 |
| β-strand | 276-277 | 2 | 29 |
| β-strand | 291-301 | 11 | 29 |
| β-strand | 325-335 | 11 | 29 |
Chain 6: 7 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 104-119 | 16 | |
| α-helix | 135-146 | 12 | |
| β-strand | 150-154 | 5 | 31 |
| α-helix | 156-159 | 4 | |
| α-helix | 167-172 | 6 | |
| α-helix | 178-189 | 12 | |
| β-strand | 264-268 | 5 | 31 |
| β-strand | 274 | 1 | 32 |
| α-helix | 281-283 | 3 | |
| β-strand | 290 | 1 | 32 |
| β-strand | 292-295 | 4 | 33 |
| β-strand | 301-303 | 3 | 19 |
| β-strand | 354-356 | 3 | 19 |
| β-strand | 357-362 | 6 | 33 |
| α-helix | 365-367 | 3 | |
| β-strand | 376-381 | 6 | 33 |
| β-strand | 394-395 | 2 | 33 |
| β-strand | 396 | 1 | 34 |
| β-strand | 401-406 | 6 | 33 |
| β-strand | 449-456 | 8 | 33 |
| β-strand | 460 | 1 | 34 |
Chain 7: 11 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 16-18 | 3 | |
| α-helix | 19-22 | 4 | |
| α-helix | 62-71 | 10 | |
| β-strand | 78-79 | 2 | 35 |
| α-helix | 83-91 | 9 | |
| α-helix | 103-109 | 7 | |
| α-helix | 112-115 | 4 | |
| α-helix | 141-153 | 13 | |
| β-strand | 202-203 | 2 | 35 |
| α-helix | 211-214 | 4 | |
| β-strand | 225 | 1 | 36 |
| α-helix | 232-234 | 3 | |
| β-strand | 238-243 | 6 | 36 |
| β-strand | 244-246 | 3 | 37 |
| β-strand | 254-255 | 2 | 38 |
| β-strand | 257 | 1 | 39 |
| β-strand | 259-261 | 3 | 40 |
| β-strand | 272 | 1 | 39 |
| β-strand | 274 | 1 | 41 |
| β-strand | 277 | 1 | 41 |
| β-strand | 278 | 1 | 24 |
| α-helix | 296-298 | 3 | |
| β-strand | 299-301 | 3 | 40 |
| β-strand | 307-308 | 2 | 38 |
| β-strand | 310-316 | 7 | 37 |
| α-helix | 327-328 | 2 | |
| β-strand | 331-336 | 6 | 37 |
| β-strand | 349-354 | 6 | 36 |
| β-strand | 355 | 1 | 37 |
| β-strand | 376-377 | 2 | 37 |
| β-strand | 380-382 | 3 | 36 |
Chain A: 7 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-20 | 15 | |
| α-helix | 35-51 | 17 | |
| α-helix | 53-57 | 5 | |
| α-helix | 69-74 | 6 | |
| α-helix | 77-103 | 27 | |
| α-helix | 127-141 | 15 | |
| α-helix | 157-158 | 2 | |
| β-strand | 162 | 1 | 1 |
| β-strand | 167 | 1 | 2 |
| β-strand | 188-189 | 2 | 3 |
| β-strand | 192 | 1 | 1 |
| β-strand | 205 | 1 | 2 |
Chain B: 8 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 20-22 | 3 | |
| β-strand | 25-27 | 3 | 4 |
| β-strand | 69-71 | 3 | 4 |
| α-helix | 78-81 | 4 | |
| β-strand | 87 | 1 | 4 |
| α-helix | 88-89 | 2 | |
| α-helix | 100-106 | 7 | |
| α-helix | 121-123 | 3 | |
| α-helix | 125-129 | 5 | |
| α-helix | 142-158 | 17 | |
| β-strand | 169 | 1 | 5 |
| α-helix | 182-196 | 15 | |
6 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| DNA replication complex GINS protein PSF1 | A | protein | 208 | Saccharomyces cerevisiae | Q12488 (AlphaFold model) |
| DNA replication complex GINS protein PSF2 | B | protein | 213 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P40359 (AlphaFold model) |
| DNA replication complex GINS protein PSF3 | C | protein | 194 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q12146 (AlphaFold model) |
| DNA replication complex GINS protein SLD5 | D | protein | 294 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q03406 (AlphaFold model) |
| Cell division control protein 45 | c | protein | 650 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q08032 |
| DNA replication licensing factor MCM2 | 2 | protein | 868 | Saccharomyces cerevisiae | P29469 |
| DNA replication licensing factor MCM3 | 3 | protein | 971 | Saccharomyces cerevisiae | P24279 |
| DNA replication licensing factor MCM4 | 4 | protein | 933 | Saccharomyces cerevisiae | P30665 |
| Minichromosome maintenance protein 5 | 5 | protein | 775 | Saccharomyces cerevisiae | P29496 |
| DNA replication licensing factor MCM6 | 6 | protein | 1017 | Saccharomyces cerevisiae | P53091 |
| DNA replication licensing factor MCM7 | 7 | protein | 845 | Saccharomyces cerevisiae | P38132 |
| DNA polymerase alpha-binding protein | E, F, G | protein | 927 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q01454 |
Sequence of entity 1 (A), FASTA
>6PTJ_1 DNA replication complex GINS protein PSF1 (chains A)
MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYHEDIIRNILKEVSNLRKNTEYLKEQQQL
GMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAWNNNGLDLMSSITFSQQDT
NNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSDVFIDVRVLKDAGEIQTEYGV
FNLIKDSQFFVRQSDVERLIQQGYLQKI
Sequence of entity 2 (B), FASTA
>6PTJ_2 DNA replication complex GINS protein PSF2 (chains B)
MSLPAHLQQTFSPEEIQFIVENEPIKIFPRITTRQKIRGDDRGTGNHTRWQLITTDDKAL
NNMVAMRSTEVVLWIALLLKQQSKCSIVAPQWLTTKELDRKIQYEKTHPDRFSELPWNWL
VLARILFNKAKDDFHDPIHELRGKIQDLREIRQIKVLKGLKYLNESHLQLDNLSLLEINE
LRPFITEIMDKLREIHTASLTAGTENDEEEFNI
Sequence of entity 3 (C), FASTA
>6PTJ_3 DNA replication complex GINS protein PSF3 (chains C)
MGYYDIDDVLADGTEFPCKFQYDIPGLGYLENNPGRPITKNTKLSLPLWLARILAIVGGD
EALVDEEPVPFVELLPPDMFSTKVMNAIKTDPVALDLHSINSHFFSLAIKWIMLFSEKEL
ANVVSELLLQRAQELNHHASSLSIDLNADSTGKNSANTNIATSTFLLKLEEMEKEIYKKS
HESYKDTKRWMFKK
Sequence of entity 4 (D), FASTA
>6PTJ_4 DNA replication complex GINS protein SLD5 (chains D)
MDINIDDILAELDKETTAVDSTKITQGSSSTTHRDANTIVGSSLDLNDKTQIYVSPQQDF
SDLMKSWKNERCSPELLPYPHQLMKRLLNRISMQSQLIENISMGFLDMQNASNANPPMPN
ESKLPLLCMETELERLKFVIRSYIRCRLSKIDKFSLYLRQLNEDENSLISLTDLLSKDEI
KYHDTHSLIWLKLVNDSILKYMPEELQAINDTEGSVNMIDEPDWNKFVFIHVNGPPDGKW
NEDPLLQENEFGKPCYTVTIPDLKEEVELTIGSIYVMRYEVIRDLLRDDKVALI
Sequence of entity 5 (c), FASTA
>6PTJ_5 Cell division control protein 45 (chains c)
MYYGISQFSEAYNKILRNSSSHSSCQLVIFVSCLNIDALCATKMLSLLFKKQLVQSQIVP
IFGYSELRRHYSQLDDNINSLLLVGFGGVIDLEAFLEIDPQEYVIDTDEKSGEQSFRRDI
YVLDAHRPWNLDNIFGSQIIQCFDDGTVDDTLGEQKEAYYKLLELDEESGDDELSGDEND
NNGGDDEATDADEVTDEDEEDEDETISNKRGNSSIGPNDLSKRKQRKKQIHEYEGVLEEY
YSQGTTVVNSISAQIYSLLSAIGETNLSNLWLNILGTTSLDIAYAQVYNRLYPLLQDEVK
RLTPSSRNSVKTPDTLTLNIQPDYYLFLLRHSSLYDSFYYSNYVNAKLSLWNENGKKRLH
KMFARMGIPLSTAQETWLYMDHSIKRELGIIFDKNLDRYGLQDIIRDGFVRTLGYRGSIS
ASEFVEALTALLEVGNSTDKDSVKINNDNNDDTDGEEEEDNSAQKLTNLRKRWVSNFWLS
WDALDDRKVELLNRGIQLAQDLQRAIFNTGVAILEKKLIKHLRIYRLCVLQDGPDLDLYR
NPLTLLRLGNWLIECCAESEDKQLLPMVLASIDENTDTYLVAGLTPRYPRGLDTIHTKKP
ILNNFSMAFQQITAETDAKVRIDNFESSIIEIRREDLSPFLEKLTLSGLL
Sequence of entity 6 (2), FASTA
>6PTJ_6 DNA replication licensing factor MCM2 (chains 2)
MSDNRRRRREEDDSDSENELPPSSPQQHFRGGMNPVSSPIGSPDMINPEGDDNEVDDVPD
IDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDREQQELSLSERRRIDAQLNERD
RLLRNVAYIDDEDEEQEGAAQLDEMGLPVQRRRRRRQYEDLENSDDDLLSDMDIDPLREE
LTLESLSNVKANSYSEWITQPNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSE
SLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDF
PTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIR
ISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKP
GEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREGNTANEGEEGLDVFSWTEEE
EREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVL
LLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLAD
KGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNST
LPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELK
NNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYARTKIYPKLHQ
MDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKV
VVDSFVDAQKVSVRRQLRRSFAIYTLGH
Sequence of entity 7 (3), FASTA
>6PTJ_7 DNA replication licensing factor MCM3 (chains 3)
MEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQ
DDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAY
FIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLV
SVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNK
LTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKS
LGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIF
DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLR
FVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTD
VDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLL
SRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINP
EEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYV
QYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKT
VNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG
SPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQL
GLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTIST
GRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNN
LMVADDKVWRV
Sequence of entity 8 (4), FASTA
>6PTJ_8 DNA replication licensing factor MCM4 (chains 4)
MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG
NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS
SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII
WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN
LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF
YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI
DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY
DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST
IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI
LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG
LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG
IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL
AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM
GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP
KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES
SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV
Sequence of entity 9 (5), FASTA
>6PTJ_9 Minichromosome maintenance protein 5 (chains 5)
MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS
LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT
SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS
IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP
YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI
YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL
SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT
AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID
EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI
DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK
RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT
ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR
RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV
Sequence of entity 10 (6), FASTA
>6PTJ_10 DNA replication licensing factor MCM6 (chains 6)
MSSPFPADTPSSNRPSNSSPPPSSIGAGFGSSSGLDSQIGSRLHFPSSSQPHVSNSQTGP
FVNDSTQFSSQRLQTDGSATNDMEGNEPARSFKSRALNHVKKVDDVTGEKVREAFEQFLE
DFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPF
LQKGLRRVVRKYAPELLNTSDSLKRSEGDEGQADEDEQQDDDMNGSSLPRDSGSSAAPGN
GTSAMATRSITTSTSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEV
RPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVR
IQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSST
LDTRGISKTTEGLNSGVTGLRSLGVRDLTYKISFLACHVISIGSNIGASSPDANSNNRET
ELQMAANLQANNVYQDNERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGH
EAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSG
KASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQT
ISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCN
EKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKEL
RKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDV
DDVEMDEEFDNIESQSHAASGNNDDNDDGTGSGVITSEPPADIEEGQSEATARPGTSEKK
KTTVTYDKYVSMMNMIVRKIAEVDREGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRL
AFKVIKRLVKDRILMEIHGTRHNLRDLENEENENNKTVYVIHPNCEVLDQLEPQDSS
Sequence of entity 11 (7), FASTA
>6PTJ_11 DNA replication licensing factor MCM7 (chains 7)
MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG
PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA
IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA
LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT
VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM
STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY
TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP
EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG
VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV
MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM
LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV
VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV
RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS
NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI
DLQDA
Sequence of entity 12 (E, F, G), FASTA
>6PTJ_12 DNA polymerase alpha-binding protein (chains E, F, G)
MVSVIDKLVFDFGGKTLVSLAPDNNTLCVANKNGLTKILKTNNPEEEPETLDSSKLVSSI
KCYSNSHFLMTTMQGDALRYNIDSSQEELLARFALPLRDCCVIHSGKMAVFGGDDLELIL
LELDDETHKKHAIKIDEQVSQISYNSQMNILAVSMINGKVQIFSLTSTIPNKVHELNDYI
VANSYDDTHRDKILSNMMDDIDKDNDNDLSETADPDENNVADPEFCAANRICTRVAWHPK
GLHFALPCADDTVKIFSIKGYSLQKTLSTNLSSTKAHFIDLQFDPLRGTYIAAVDLNNKL
TVWNWETSEIHYTREFKRKITNIAWKIQADSKTLDLVLGTWSGSIAIVQNLAESVVSNIP
DQSVAESSTKHGLFVDSESDLENLEGNDDINKSDKLFSDITQEANAEDVFTQTHDGPSGL
SEKRKYNFEDEEDFIDDDDGAGYISGKKPHNEHSYSRVHKTHSFPISLANTGKFRYMPFS
PAGTPFGFTDRRYLTMNEVGYVSTVKNSEQYSITVSFFDVGRFREYHFEDLFGYDLCFLN
EKGTLFGQSKTGQIQYRPHDSIHSNWTKIIPLQAGERITSVAATPVRVIVGTSLGYFRSF
NQFGVPFAVEKTSPIVALTAQNYRVFSVHYSQFHGLSYSLSELGTSSKRYYKRECPLPMS
LPNINSDMKKDANLDYYNFNPMGIKSLFFSSYGDPCIFGSDNTLLLLSKWRSPEESKWLP
ILDSNMEIWKMSGGKETTDIHVWPLALAYDTLNCILVKGKHIWPEFPLPLPSEMEIRMPV
FVKSKLLEENKAILNKKNEIGADTEAEEGEEDKEIQIPVSMAAEEEYLRSKVLSELLTDT
LENDGEMYGNENEVLAALNGAYDKALLRLFASACSDQNVEKALSLAHELKQDRALTAAVK
ISERAELPSLVKKINNIREARYEQQLK
Primary citation
Ctf4 organizes sister replisomes and Pol alpha into a replication factory. Yuan, Z., Georgescu, R., Santos, R.L.A. et al. Elife (2019) 8. DOI 10.7554/eLife.47405 · PubMed
Other PDB entries of the same protein (UniProt Q12488 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 28VY 2.7 Å, sCMGE assembled on ARS1 DNA with Sld2 and RPA
- 8KG6 3.07 Å, Yeast replisome in state I
- 7PMK 3.2 Å, S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)
- 7PMN 3.2 Å, S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II)
- 9E2Y 3.2 Å, Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 3
- 9RHI 3.2 Å, pre-Initiation Complex on ARS1 DNA (monomer)
- 9E2W 3.3 Å, Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 1
- 9RHJ 3.4 Å, Pre-Initiation Complex on ARS1 DNA (dimer)
- 8B9A 3.5 Å, S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork…
- 8B9B 3.5 Å, S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA…
- 9E2X 3.5 Å, Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 2
- 3JC6 3.7 Å, Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Browse structure collections
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