7PER: Nucleoporin p54
Model of the inner ring of the human nuclear pore complex. Determined by electron microscopy at 35.0 Å resolution. Released 20 Oct 2021.
- Method
- Electron microscopy
- Resolution
- 35.0 Å
- Organism
- Homo sapiens
- Chains
- 24
- Atoms
- 67,036
- Mol. weight
- 2587.41 kDa
- Released
- 20 Oct 2021
Explore 7PER in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7PER contains 676 α-helices and 234 β-strands across 24 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chains C, I and U: 35 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 177-198 | 22 | |
| α-helix | 204-212 | 9 | |
| α-helix | 220-229 | 10 | |
| α-helix | 254-274 | 21 | |
| α-helix | 289-299 | 11 | |
| β-strand | 312-313 | 2 | 66 |
| β-strand | 316-317 | 2 | 66 |
| α-helix | 318-328 | 11 | |
| α-helix | 331-340 | 10 | |
| α-helix | 347-352 | 6 | |
| α-helix | 369-374 | 6 | |
| α-helix | 375-379 | 5 | |
| α-helix | 385-395 | 11 | |
| α-helix | 410-420 | 11 | |
| α-helix | 437-446 | 10 | |
| α-helix | 449-452 | 4 | |
| α-helix | 462-469 | 8 | |
| α-helix | 472-479 | 8 | |
| α-helix | 486-498 | 13 | |
| α-helix | 528-539 | 12 | |
| α-helix | 544-552 | 9 | |
| α-helix | 553-556 | 4 | |
| α-helix | 562-577 | 16 | |
| α-helix | 580-584 | 5 | |
| β-strand | 585-586 | 2 | 67 |
| α-helix | 593 | 1 | |
| β-strand | 594-595 | 2 | 67 |
| α-helix | 597-601 | 5 | |
| α-helix | 606-619 | 14 | |
| α-helix | 624-632 | 9 | |
| α-helix | 635-646 | 12 | |
| α-helix | 663-675 | 13 | |
| α-helix | 683-701 | 19 | |
| α-helix | 707-717 | 11 | |
| α-helix | 729-735 | 7 | |
| α-helix | 739-759 | 21 | |
| α-helix | 761-763 | 3 | |
| α-helix | 787-798 | 12 | |
| α-helix | 809-813 | 5 | |
Chain D: 64 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 15-24 | 10 | |
| α-helix | 41-44 | 4 | |
| β-strand | 58 | 1 | 34 |
| α-helix | 61-68 | 8 | |
| β-strand | 71-73 | 3 | 35 |
| β-strand | 83-85 | 3 | 35 |
| α-helix | 88-101 | 14 | |
| β-strand | 103 | 1 | 34 |
| α-helix | 105-114 | 10 | |
| α-helix | 130-152 | 23 | |
| α-helix | 165-172 | 8 | |
| α-helix | 182-194 | 13 | |
| α-helix | 197-205 | 9 | |
| α-helix | 211-238 | 28 | |
| α-helix | 243-255 | 13 | |
| α-helix | 268-280 | 13 | |
| α-helix | 305-317 | 13 | |
| α-helix | 324-341 | 18 | |
| α-helix | 344-349 | 6 | |
| α-helix | 352 | 1 | |
| α-helix | 353-357 | 5 | |
| α-helix | 358-365 | 8 | |
| α-helix | 368-378 | 11 | |
| α-helix | 385-402 | 18 | |
| α-helix | 404-417 | 14 | |
| α-helix | 430-435 | 6 | |
| α-helix | 438-450 | 13 | |
| α-helix | 461-464 | 4 | |
| α-helix | 494-502 | 9 | |
| α-helix | 507-520 | 14 | |
| α-helix | 524-535 | 12 | |
| α-helix | 555-572 | 18 | |
| α-helix | 592-610 | 19 | |
| α-helix | 614-619 | 6 | |
| α-helix | 626-635 | 10 | |
| α-helix | 643-653 | 11 | |
| α-helix | 658-660 | 3 | |
| α-helix | 661-669 | 9 | |
| α-helix | 687-697 | 11 | |
| α-helix | 701-715 | 15 | |
| β-strand | 725 | 1 | 36 |
| β-strand | 728 | 1 | 36 |
| α-helix | 733-743 | 11 | |
| α-helix | 755-774 | 20 | |
| α-helix | 778-782 | 5 | |
| α-helix | 793-798 | 6 | |
| α-helix | 801-810 | 10 | |
| α-helix | 815-824 | 10 | |
| α-helix | 840-858 | 19 | |
| α-helix | 860-861 | 2 | |
| α-helix | 862-867 | 6 | |
| α-helix | 868-871 | 4 | |
| α-helix | 880-886 | 7 | |
| α-helix | 893-904 | 12 | |
| α-helix | 910-923 | 14 | |
| α-helix | 1394-1409 | 16 | |
| α-helix | 1415-1432 | 18 | |
| α-helix | 1438-1448 | 11 | |
| β-strand | 1451 | 1 | 37 |
| α-helix | 1458-1516 | 59 | |
| α-helix | 1517-1521 | 5 | |
| α-helix | 1522-1538 | 17 | |
| α-helix | 1545-1564 | 20 | |
| α-helix | 1567-1575 | 9 | |
| α-helix | 1578-1585 | 8 | |
| α-helix | 1592-1594 | 3 | |
| α-helix | 1610-1632 | 23 | |
| α-helix | 1640-1651 | 12 | |
| α-helix | 1655-1659 | 5 | |
| β-strand | 1660 | 1 | 39 |
| α-helix | 1665-1683 | 19 | |
| α-helix | 1687-1690 | 4 | |
Chains E, Q and W: 46 helices, 38 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-39 | 18 | |
| α-helix | 46-49 | 4 | |
| β-strand | 63-64 | 2 | 74 |
| β-strand | 81-88 | 8 | 75 |
| α-helix | 89-90 | 2 | |
| α-helix | 91-95 | 5 | |
| β-strand | 104-109 | 6 | 76 |
| β-strand | 114-119 | 6 | 76 |
| β-strand | 122-127 | 6 | 76 |
| β-strand | 134-137 | 4 | 76 |
| β-strand | 146-150 | 5 | 77 |
| α-helix | 151-153 | 3 | |
| β-strand | 163-168 | 6 | 77 |
| β-strand | 172-180 | 9 | 77 |
| β-strand | 198-202 | 5 | 77 |
| β-strand | 208-209 | 2 | 77 |
| β-strand | 215-220 | 6 | 78 |
| β-strand | 226-230 | 5 | 78 |
| β-strand | 236-238 | 3 | 78 |
| β-strand | 255-256 | 2 | 78 |
| β-strand | 279-285 | 7 | 79 |
| β-strand | 290-295 | 6 | 79 |
| β-strand | 300-306 | 7 | 79 |
| β-strand | 309-311 | 3 | 79 |
| β-strand | 317-318 | 2 | 79 |
| α-helix | 320-327 | 8 | |
| β-strand | 344-347 | 4 | 80 |
| β-strand | 356-361 | 6 | 80 |
| β-strand | 367-371 | 5 | 80 |
| β-strand | 375 | 1 | 81 |
| β-strand | 381 | 1 | 81 |
| β-strand | 386-391 | 6 | 80 |
| β-strand | 406 | 1 | 74 |
| β-strand | 411-413 | 3 | 74 |
| β-strand | 417-423 | 7 | 74 |
| β-strand | 429-436 | 8 | 74 |
| β-strand | 447-452 | 6 | 74 |
| β-strand | 460-463 | 4 | 75 |
| α-helix | 496-498 | 3 | |
| β-strand | 499-503 | 5 | 75 |
| β-strand | 507-513 | 7 | 75 |
| α-helix | 514-515 | 2 | |
| α-helix | 516-522 | 7 | |
| α-helix | 536-542 | 7 | |
| α-helix | 544-556 | 13 | |
| α-helix | 564-576 | 13 | |
| α-helix | 661-679 | 19 | |
| β-strand | 681 | 1 | 82 |
| β-strand | 683 | 1 | 83 |
| β-strand | 700 | 1 | 83 |
| α-helix | 704-723 | 20 | |
| α-helix | 725-728 | 4 | |
| α-helix | 770-800 | 31 | |
| α-helix | 803-810 | 8 | |
| α-helix | 815-819 | 5 | |
| β-strand | 822 | 1 | 82 |
| α-helix | 823-827 | 5 | |
| α-helix | 831-843 | 13 | |
| α-helix | 850-862 | 13 | |
| α-helix | 872-886 | 15 | |
| α-helix | 899-907 | 9 | |
| α-helix | 912-922 | 11 | |
| α-helix | 926-940 | 15 | |
| α-helix | 945-952 | 8 | |
| α-helix | 962-982 | 21 | |
| α-helix | 1016-1024 | 9 | |
| α-helix | 1035-1046 | 12 | |
| α-helix | 1049-1054 | 6 | |
| α-helix | 1060-1067 | 8 | |
| α-helix | 1077-1087 | 11 | |
| α-helix | 1091-1103 | 13 | |
| α-helix | 1111-1123 | 13 | |
| α-helix | 1140-1163 | 24 | |
| α-helix | 1173-1180 | 8 | |
| α-helix | 1185-1186 | 2 | |
| α-helix | 1187-1193 | 7 | |
| α-helix | 1199-1209 | 11 | |
| α-helix | 1214-1231 | 18 | |
| α-helix | 1237-1255 | 19 | |
| α-helix | 1264-1276 | 13 | |
| α-helix | 1284-1292 | 9 | |
| α-helix | 1296-1309 | 14 | |
| α-helix | 1321-1336 | 16 | |
| α-helix | 1356-1363 | 8 | |
Chain F: 13 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 129-140 | 12 | |
| β-strand | 154-157 | 4 | 1 |
| β-strand | 191-195 | 5 | 2 |
| α-helix | 199-217 | 19 | |
| β-strand | 224-231 | 8 | 2 |
| β-strand | 238-247 | 10 | 2 |
| β-strand | 253-255 | 3 | 2 |
| α-helix | 256-257 | 2 | |
| α-helix | 258-266 | 9 | |
| α-helix | 268-277 | 10 | |
| β-strand | 279-284 | 6 | 2 |
| α-helix | 291-297 | 7 | |
| α-helix | 306-315 | 10 | |
| β-strand | 323-326 | 4 | 1 |
| α-helix | 329-396 | 68 | |
| α-helix | 407-421 | 15 | |
| α-helix | 422-426 | 5 | |
| α-helix | 427-450 | 24 | |
| α-helix | 455-457 | 3 | |
| β-strand | 461 | 1 | 3 |
| α-helix | 463-490 | 28 | |
Chains G, M, S and Y: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 249-275 | 27 | |
| α-helix | 279-321 | 43 | |
| α-helix | 326-328 | 3 | |
| α-helix | 331-334 | 4 | |
| α-helix | 342-376 | 35 | |
| α-helix | 383-417 | 35 | |
Chains H, N, T and Z: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 335-405 | 71 | |
| α-helix | 411-422 | 12 | |
| α-helix | 432-460 | 29 | |
| α-helix | 471-498 | 28 | |
| α-helix | 499-501 | 3 | |
Chain J: 64 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 15-24 | 10 | |
| α-helix | 41-44 | 4 | |
| β-strand | 58 | 1 | 40 |
| α-helix | 61-68 | 8 | |
| β-strand | 71-73 | 3 | 41 |
| β-strand | 83-85 | 3 | 41 |
| α-helix | 88-101 | 14 | |
| β-strand | 103 | 1 | 40 |
| α-helix | 105-114 | 10 | |
| α-helix | 130-152 | 23 | |
| α-helix | 165-172 | 8 | |
| α-helix | 182-194 | 13 | |
| α-helix | 197-205 | 9 | |
| α-helix | 211-238 | 28 | |
| α-helix | 243-255 | 13 | |
| α-helix | 268-280 | 13 | |
| α-helix | 305-317 | 13 | |
| α-helix | 324-341 | 18 | |
| α-helix | 344-349 | 6 | |
| α-helix | 352 | 1 | |
| α-helix | 353-357 | 5 | |
| α-helix | 358-365 | 8 | |
| α-helix | 368-378 | 11 | |
| α-helix | 385-402 | 18 | |
| α-helix | 404-417 | 14 | |
| α-helix | 430-435 | 6 | |
| α-helix | 438-450 | 13 | |
| α-helix | 461-464 | 4 | |
| α-helix | 494-502 | 9 | |
| α-helix | 507-520 | 14 | |
| α-helix | 524-535 | 12 | |
| α-helix | 555-572 | 18 | |
| α-helix | 592-610 | 19 | |
| α-helix | 614-619 | 6 | |
| α-helix | 626-635 | 10 | |
| α-helix | 643-653 | 11 | |
| α-helix | 658-660 | 3 | |
| α-helix | 661-669 | 9 | |
| α-helix | 687-697 | 11 | |
| α-helix | 701-715 | 15 | |
| β-strand | 725 | 1 | 42 |
| β-strand | 728 | 1 | 42 |
| α-helix | 733-743 | 11 | |
| α-helix | 755-774 | 20 | |
| α-helix | 778-782 | 5 | |
| α-helix | 793-798 | 6 | |
| α-helix | 801-810 | 10 | |
| α-helix | 815-824 | 10 | |
| α-helix | 840-858 | 19 | |
| α-helix | 860-861 | 2 | |
| α-helix | 862-867 | 6 | |
| α-helix | 868-871 | 4 | |
| α-helix | 880-886 | 7 | |
| α-helix | 893-904 | 12 | |
| α-helix | 910-923 | 14 | |
| α-helix | 1394-1409 | 16 | |
| α-helix | 1415-1432 | 18 | |
| α-helix | 1438-1448 | 11 | |
| β-strand | 1451 | 1 | 44 |
| α-helix | 1458-1516 | 59 | |
| α-helix | 1517-1521 | 5 | |
| α-helix | 1522-1538 | 17 | |
| α-helix | 1545-1564 | 20 | |
| α-helix | 1567-1575 | 9 | |
| α-helix | 1578-1585 | 8 | |
| α-helix | 1592-1594 | 3 | |
| α-helix | 1610-1632 | 23 | |
| α-helix | 1640-1651 | 12 | |
| α-helix | 1655-1659 | 5 | |
| α-helix | 1665-1683 | 19 | |
| α-helix | 1687-1690 | 4 | |
Chain K: 46 helices, 39 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-39 | 18 | |
| α-helix | 46-49 | 4 | |
| β-strand | 63-64 | 2 | 56 |
| β-strand | 81-88 | 8 | 57 |
| α-helix | 89-90 | 2 | |
| α-helix | 91-95 | 5 | |
| β-strand | 104-109 | 6 | 58 |
| β-strand | 114-119 | 6 | 58 |
| β-strand | 122-127 | 6 | 58 |
| β-strand | 134-137 | 4 | 58 |
| β-strand | 146-150 | 5 | 59 |
| α-helix | 151-153 | 3 | |
| β-strand | 163-168 | 6 | 59 |
| β-strand | 172-180 | 9 | 59 |
| β-strand | 198-202 | 5 | 59 |
| β-strand | 208-209 | 2 | 59 |
| β-strand | 215-220 | 6 | 60 |
| β-strand | 226-230 | 5 | 60 |
| β-strand | 236-238 | 3 | 60 |
| β-strand | 255-256 | 2 | 60 |
| β-strand | 279-285 | 7 | 61 |
| β-strand | 290-295 | 6 | 61 |
| β-strand | 300-306 | 7 | 61 |
| β-strand | 309-311 | 3 | 61 |
| β-strand | 317-318 | 2 | 61 |
| α-helix | 320-327 | 8 | |
| β-strand | 344-347 | 4 | 62 |
| β-strand | 356-361 | 6 | 62 |
| β-strand | 367-371 | 5 | 62 |
| β-strand | 375 | 1 | 63 |
| β-strand | 381 | 1 | 63 |
| β-strand | 386-391 | 6 | 62 |
| β-strand | 406 | 1 | 56 |
| β-strand | 411-413 | 3 | 56 |
| β-strand | 417-423 | 7 | 56 |
| β-strand | 429-436 | 8 | 56 |
| β-strand | 447-452 | 6 | 56 |
| β-strand | 460-463 | 4 | 57 |
| α-helix | 496-498 | 3 | |
| β-strand | 499-503 | 5 | 57 |
| β-strand | 507-513 | 7 | 57 |
| α-helix | 514-515 | 2 | |
| α-helix | 516-522 | 7 | |
| α-helix | 536-542 | 7 | |
| α-helix | 544-556 | 13 | |
| α-helix | 564-576 | 13 | |
| α-helix | 661-679 | 19 | |
| β-strand | 681 | 1 | 64 |
| β-strand | 683 | 1 | 65 |
| β-strand | 700 | 1 | 65 |
| α-helix | 704-723 | 20 | |
| α-helix | 725-728 | 4 | |
| α-helix | 770-800 | 31 | |
| α-helix | 803-810 | 8 | |
| α-helix | 815-819 | 5 | |
| β-strand | 822 | 1 | 64 |
| α-helix | 823-827 | 5 | |
| α-helix | 831-843 | 13 | |
| α-helix | 850-862 | 13 | |
| α-helix | 872-886 | 15 | |
| α-helix | 899-907 | 9 | |
| α-helix | 912-922 | 11 | |
| α-helix | 926-940 | 15 | |
| α-helix | 945-952 | 8 | |
| α-helix | 962-982 | 21 | |
| α-helix | 1016-1024 | 9 | |
| α-helix | 1035-1046 | 12 | |
| α-helix | 1049-1054 | 6 | |
| α-helix | 1060-1067 | 8 | |
| α-helix | 1077-1087 | 11 | |
| α-helix | 1091-1103 | 13 | |
| α-helix | 1111-1123 | 13 | |
| α-helix | 1140-1163 | 24 | |
| α-helix | 1173-1180 | 8 | |
| α-helix | 1185-1186 | 2 | |
| α-helix | 1187-1193 | 7 | |
| α-helix | 1199-1209 | 11 | |
| α-helix | 1214-1231 | 18 | |
| α-helix | 1237-1255 | 19 | |
| α-helix | 1264-1276 | 13 | |
| α-helix | 1284-1292 | 9 | |
| α-helix | 1296-1309 | 14 | |
| α-helix | 1321-1336 | 16 | |
| β-strand | 1339 | 1 | 43 |
| α-helix | 1356-1363 | 8 | |
4 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Nucleoporin p54 | F, L, R, X | protein | 507 | Homo sapiens | Q7Z3B4 (AlphaFold model) |
| Nucleoporin p58/p45 | G, M, S, Y | protein | 599 | Homo sapiens | Q9BVL2 (AlphaFold model) |
| Nuclear pore glycoprotein p62 | H, N, T, Z | protein | 522 | Homo sapiens | P37198 (AlphaFold model) |
| Nuclear pore complex protein Nup205 | D, J, P, V | protein | 2012 | Homo sapiens | Q92621 (AlphaFold model) |
| Nuclear pore complex protein Nup155 | E, K, Q, W | protein | 1391 | Homo sapiens | O75694 |
| Nuclear pore complex protein Nup93 | C, I, O, U | protein | 819 | Homo sapiens | Q8N1F7 |
Sequence of entity 1 (F, L, R, X), FASTA
>7PER_1 Nucleoporin p54 (chains F, L, R, X)
MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG
FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT
ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC
MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV
VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP
PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE
LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE
LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI
IKDDLEDIKLVEHGLNETIHIRGGVFS
Sequence of entity 2 (G, M, S, Y), FASTA
>7PER_2 Nucleoporin p58/p45 (chains G, M, S, Y)
MSTGFSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATTSAPS
SGFGTGLFGSKPATGFTLGGTNTGIATTITTGLTLGTPATTSAATTGFSLGFNKPAASAT
PFALPITSTSASGLTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLGGALAGLGG
SLFQSTNTGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDKKSDKTGTRPEDSK
ALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAANG
IQRNTLNIDKLKIETAQELKNAEIALRTQKTPPGLQHEYAAPADYFRILVQQFEVQLQQY
RQQIEELENHLATQANNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLKEQYLGY
RKMFLGDAVDVFETRRAEAKKWQNTPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGP
QPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCSTTGASTFGFGTTNKPSGS
LSAGFGSSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGGQLLQLKKPPAGNKRGKR
Sequence of entity 3 (H, N, T, Z), FASTA
>7PER_3 Nuclear pore glycoprotein p62 (chains H, N, T, Z)
MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLF
SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN
LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA
QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC
TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPA
GIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNA
WDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGT
IYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNA
HMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD
Sequence of entity 4 (D, J, P, V), FASTA
>7PER_4 Nuclear pore complex protein Nup205 (chains D, J, P, V)
MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKN
VQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQP
HFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQ
GLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSP
LGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPL
LTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMA
ELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARM
IHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYL
GVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSS
HVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAF
LQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIA
ASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFP
SNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQL
EDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKK
HLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIA
RYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDA
EEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNL
QDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPT
MRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLL
HLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQ
LDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEIS
TVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHD
KILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPP
EENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDT
LEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALL
DRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFL
TRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQIL
LPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGII
SKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEG
DKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQ
APVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMP
AGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDS
QDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLL
DIEGLYSKVRSRYSFIQALVRRIRGLLRISRN
Sequence of entity 5 (E, K, Q, W), FASTA
>7PER_5 Nuclear pore complex protein Nup155 (chains E, K, Q, W)
MPSSLLGAAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGM
SDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTID
SDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSY
ANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAY
QAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGVI
QVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLA
VTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLM
AASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDH
IPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFK
LHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILGS
PVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYS
GKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEF
LDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQA
IQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIAS
LINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRES
LKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIV
GLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHF
EQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDL
LWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEF
LHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAE
CKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPR
FFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKP
LHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNF
KSLQAKLERLH
Sequence of entity 6 (C, I, O, U), FASTA
>7PER_6 Nuclear pore complex protein Nup93 (chains C, I, O, U)
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKA
SVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKR
TFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDN
IEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKSISDMWTMVKQMTDVLLTPATD
ALKNRSSVEVRMEFVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIK
LPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKD
RRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQ
VCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAVAFLF
RMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCLRRLNFVRLLMLYTRKFE
STDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDK
FTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNK
ERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLV
PLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSSRPQRVIED
RDSQLRSQARTLITFAGMIPYRTSGDTNARLVQMEVLMN
Primary citation
The cellular environment shapes the nuclear pore complex architecture. Schuller, A.P., Wojtynek, M., Mankus, D. et al. Nature (2021) 598:667-671. DOI 10.1038/s41586-021-03985-3 · PubMed
Other PDB entries of the same protein (UniProt Q7Z3B4 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7N8R 1.2 Å, FGTGFG segment from the Nucleoporin p54, residues 63-68
- 4JNU 1.45 Å, Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21
- 4JO7 1.75 Å, Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry
- 4JNV 1.85 Å, Crystal structure of the human Nup57CCS3* coiled-coil segment, space group C2
- 4JO9 2.5 Å, Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex 1:2 stoichiometry
- 7R5K 12.0 Å, Human nuclear pore complex (constricted)
- 5IJN 21.4 Å, Composite structure of the inner ring of the human nuclear pore complex (32 copies of…
- 5IJO 21.4 Å, Alternative composite structure of the inner ring of the human nuclear pore complex (16…
- 7R5J 50.0 Å, Human nuclear pore complex (dilated)
- 9A25 Molecular assembly pathway of the human Nuclear Pore Complex after cell division
- 9A8T Integrative spatiotemporal modeling of biomolecular processes: application to the…
Browse structure collections
About this viewer
MolViewer shows 7PER directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.