7QJ5: Recombinant human gamma-Tubulin Ring Complex
Structure of recombinant human gamma-Tubulin Ring Complex (spokes 1-14). Determined by electron microscopy at 8.7 Å resolution. Released 26 Jan 2022.
- Method
- Electron microscopy
- Resolution
- 8.7 Å
- Organism
- Homo sapiens
- Chains
- 41
- Atoms
- 126,600
- Mol. weight
- 3047.37 kDa
- Released
- 26 Jan 2022
Explore 7QJ5 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7QJ5 contains 720 α-helices and 329 β-strands across 41 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chains 1, 2, O, P, Q, R, S, T, U, V, W, X, Y and Z: 18 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5-9 | 5 | 1 |
| α-helix | 12-28 | 17 | |
| β-strand | 31 | 1 | 2 |
| α-helix | 36 | 1 | |
| β-strand | 37 | 1 | 2 |
| α-helix | 38 | 1 | |
| β-strand | 52-54 | 3 | 3 |
| β-strand | 60-62 | 3 | 3 |
| β-strand | 64-66 | 3 | 1 |
| α-helix | 73-78 | 6 | |
| α-helix | 104-113 | 10 | |
| α-helix | 115-128 | 14 | |
| β-strand | 134-140 | 7 | 1 |
| α-helix | 149-160 | 12 | |
| β-strand | 165-172 | 8 | 1 |
| α-helix | 184-198 | 15 | |
| β-strand | 201-206 | 6 | 1 |
| α-helix | 207-217 | 11 | |
| α-helix | 224-244 | 21 | |
| α-helix | 253-257 | 5 | |
| β-strand | 263 | 1 | 4 |
| β-strand | 266 | 1 | 4 |
| β-strand | 268-269 | 2 | 1 |
| β-strand | 270-273 | 4 | 5 |
| α-helix | 290-298 | 9 | |
| β-strand | 317-325 | 9 | 5 |
| α-helix | 330-332 | 3 | |
| α-helix | 333-343 | 11 | |
| β-strand | 356-361 | 6 | 5 |
| α-helix | 362-364 | 3 | |
| β-strand | 374-381 | 8 | 5 |
| α-helix | 384-401 | 18 | |
| α-helix | 409-414 | 6 | |
| α-helix | 420-439 | 20 | |
Chain a: 5 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-20 | 12 | |
| α-helix | 30-39 | 10 | |
| β-strand | 48 | 1 | 50 |
| α-helix | 51-64 | 14 | |
| α-helix | 68-84 | 17 | |
| α-helix | 90-99 | 10 | |
| β-strand | 122 | 1 | 50 |
Chain A: 29 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 152-167 | 16 | |
| α-helix | 173-178 | 6 | |
| α-helix | 180-183 | 4 | |
| α-helix | 205-207 | 3 | |
| α-helix | 210-225 | 16 | |
| β-strand | 234-236 | 3 | 31 |
| α-helix | 237-238 | 2 | |
| β-strand | 245-247 | 3 | 31 |
| α-helix | 254-279 | 26 | |
| α-helix | 283-285 | 3 | |
| α-helix | 287-315 | 29 | |
| α-helix | 321-327 | 7 | |
| α-helix | 329-346 | 18 | |
| α-helix | 354-361 | 8 | |
| α-helix | 372-395 | 24 | |
| β-strand | 410-411 | 2 | 32 |
| β-strand | 432-433 | 2 | 32 |
| α-helix | 444-446 | 3 | |
| α-helix | 447-463 | 17 | |
| β-strand | 477 | 1 | 33 |
| β-strand | 482 | 1 | 33 |
| α-helix | 483-505 | 23 | |
| α-helix | 509-519 | 11 | |
| α-helix | 526-540 | 15 | |
| α-helix | 548-561 | 14 | |
| α-helix | 563-566 | 4 | |
| α-helix | 568-570 | 3 | |
| β-strand | 574 | 1 | 34 |
| β-strand | 619 | 1 | 34 |
| α-helix | 632-662 | 31 | |
| α-helix | 677-696 | 20 | |
| α-helix | 697-702 | 6 | |
| α-helix | 703-709 | 7 | |
| α-helix | 719-735 | 17 | |
| α-helix | 747-762 | 16 | |
| α-helix | 815-842 | 28 | |
| α-helix | 852-859 | 8 | |
Chains b and k: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-34 | 22 | |
| α-helix | 41-53 | 13 | |
| α-helix | 57-67 | 11 | |
Chain B: 28 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 247-259 | 13 | |
| β-strand | 266-268 | 3 | 35 |
| β-strand | 275-277 | 3 | 35 |
| α-helix | 288-313 | 26 | |
| α-helix | 321-330 | 10 | |
| α-helix | 332-344 | 13 | |
| α-helix | 372-387 | 16 | |
| α-helix | 393-396 | 4 | |
| α-helix | 398-402 | 5 | |
| α-helix | 415-433 | 19 | |
| β-strand | 448-450 | 3 | 36 |
| α-helix | 459-462 | 4 | |
| β-strand | 464-466 | 3 | 36 |
| α-helix | 477-487 | 11 | |
| α-helix | 490-495 | 6 | |
| α-helix | 530-548 | 19 | |
| α-helix | 555-561 | 7 | |
| α-helix | 562-566 | 5 | |
| α-helix | 572-580 | 9 | |
| α-helix | 582-586 | 5 | |
| β-strand | 588 | 1 | 37 |
| α-helix | 594-607 | 14 | |
| α-helix | 615-620 | 6 | |
| β-strand | 623-624 | 2 | 38 |
| α-helix | 627-629 | 3 | |
| β-strand | 633 | 1 | 37 |
| β-strand | 639-640 | 2 | 38 |
| α-helix | 654-686 | 33 | |
| α-helix | 698-721 | 24 | |
| α-helix | 722-727 | 6 | |
| α-helix | 728-739 | 12 | |
| α-helix | 744-761 | 18 | |
| α-helix | 769-814 | 46 | |
| α-helix | 826-838 | 13 | |
| α-helix | 840-864 | 25 | |
| α-helix | 871-880 | 10 | |
Chain c: 9 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-14 | 11 | |
| α-helix | 33-43 | 11 | |
| α-helix | 47-50 | 4 | |
| α-helix | 68-79 | 12 | |
| α-helix | 83-95 | 13 | |
| α-helix | 108-114 | 7 | |
| α-helix | 158-164 | 7 | |
| α-helix | 166-182 | 17 | |
| α-helix | 185 | 1 | |
Chain C: 32 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 152-167 | 16 | |
| α-helix | 174-177 | 4 | |
| α-helix | 180-183 | 4 | |
| α-helix | 185-187 | 3 | |
| α-helix | 210-224 | 15 | |
| β-strand | 233-234 | 2 | 39 |
| β-strand | 247-248 | 2 | 39 |
| α-helix | 254-277 | 24 | |
| α-helix | 289-292 | 4 | |
| α-helix | 297-315 | 19 | |
| α-helix | 321-327 | 7 | |
| α-helix | 330-332 | 3 | |
| α-helix | 338-345 | 8 | |
| α-helix | 353-358 | 6 | |
| α-helix | 373-382 | 10 | |
| α-helix | 384-394 | 11 | |
| β-strand | 409-410 | 2 | 40 |
| β-strand | 433-434 | 2 | 40 |
| α-helix | 441-443 | 3 | |
| α-helix | 447-462 | 16 | |
| α-helix | 487-505 | 19 | |
| α-helix | 509-519 | 11 | |
| α-helix | 526-534 | 9 | |
| α-helix | 536-540 | 5 | |
| α-helix | 548-561 | 14 | |
| α-helix | 570-572 | 3 | |
| β-strand | 573-577 | 5 | 41 |
| β-strand | 616-620 | 5 | 41 |
| α-helix | 624-627 | 4 | |
| α-helix | 632-662 | 31 | |
| α-helix | 679-696 | 18 | |
| α-helix | 697-702 | 6 | |
| α-helix | 703-713 | 11 | |
| α-helix | 719-736 | 18 | |
| α-helix | 747-759 | 13 | |
| α-helix | 766-768 | 3 | |
| α-helix | 817-842 | 26 | |
| α-helix | 854-859 | 6 | |
Chain d: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 18-34 | 17 | |
| α-helix | 41-51 | 11 | |
| α-helix | 57-72 | 16 | |
18 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Tubulin gamma-1 chain | 1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z | protein | 451 | Homo sapiens | P23258 (AlphaFold model) |
| actin, cytoplasmic 1 | e | protein | 375 | Homo sapiens | A0A6I9HGD1 (AlphaFold model) |
| Gamma-tubulin complex component 2 | A, C, E, G, M | protein | 902 | Homo sapiens | Q9BSJ2 (AlphaFold model) |
| Gamma-tubulin complex component 3 | B, D, F, H, N, a, f, h, j | protein | 907 | Homo sapiens | Q96CW5 (AlphaFold model) |
| Mitotic-spindle organizing protein 1 | b, d, g, i, k, m | protein | 82 | Homo sapiens | Q08AG7 |
| Gamma-tubulin complex component 4 | I, K | protein | 667 | Homo sapiens | Q9UGJ1 |
| Gamma-tubulin complex component 5 | J, l | protein | 1024 | Homo sapiens | Q96RT8 |
| Gamma-tubulin complex component 6 | L, c | protein | 1819 | Homo sapiens | Q96RT7 |
Sequence of entity 1 (1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z), FASTA
>7QJ5_1 Tubulin gamma-1 chain (chains 1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z)
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE
MDTSREIVQQLIDEYHAATRPDYISWGTQEQ
Sequence of entity 2 (e), FASTA
>7QJ5_2 actin, cytoplasmic 1 (chains e)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF
Sequence of entity 3 (A, C, E, G, M), FASTA
>7QJ5_3 Gamma-tubulin complex component 2 (chains A, C, E, G, M)
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG
RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV
KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH
DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ
EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK
ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR
KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM
AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI
SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID
DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL
EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL
SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT
AQ
Sequence of entity 4 (B, D, F, H, N, a, f, h, j), FASTA
>7QJ5_4 Gamma-tubulin complex component 3 (chains B, D, F, H, N, a, f, h, j)
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKK
ELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQ
ALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSL
LPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTG
GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWL
HNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLES
SLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILS
LVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQS
RKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFE
TSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI
LETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHY
LRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQY
YITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFD
QIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESI
PKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTR
GRRSSHT
Sequence of entity 5 (b, d, g, i, k, m), FASTA
>7QJ5_5 Mitotic-spindle organizing protein 1 (chains b, d, g, i, k, m)
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEAL
SSVIKELRKATEALKAAENMTS
Sequence of entity 6 (I, K), FASTA
>7QJ5_6 Gamma-tubulin complex component 4 (chains I, K)
MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIE
QYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSIS
HVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCH
GVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQD
LRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSIL
KNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDF
YLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEY
HGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFK
YLLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQ
FSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQN
LGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGG
TLGSFGM
Sequence of entity 7 (J, l), FASTA
>7QJ5_7 Gamma-tubulin complex component 5 (chains J, l)
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHK
IEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDS
PSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSRE
DSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHS
NLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNI
IVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRT
YQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGV
AEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWI
VHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQG
PSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESV
QSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDF
HEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYL
QAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSIS
FENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDV
LLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNY
IMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAG
MEQS
Sequence of entity 8 (L, c), FASTA
>7QJ5_8 Gamma-tubulin complex component 6 (chains L, c)
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPD
MSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGS
GPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQ
VMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNAD
LSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERV
GCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVL
IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLD
SLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVG
AVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWV
YSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGK
TINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEE
KELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERR
QAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALW
RIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGG
QGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFL
PVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPA
VATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQ
PTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTH
GHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNA
SIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGE
SVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVV
STRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPR
LPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDL
SPNWPLNSQEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSE
PPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVN
KAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNS
VLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGC
VSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVI
QGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSI
FSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQ
PHLEDFLLRINFNNYYQDA
Primary citation
Modular assembly of the principal microtubule nucleator gamma-TuRC. Wurtz, M., Zupa, E., Atorino, E.S. et al. Nat Commun (2022) 13:473-473. DOI 10.1038/s41467-022-28079-0 · PubMed
Other PDB entries of the same protein (UniProt P23258 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 3CB2 2.3 Å, Crystal structure of human gamma-tubulin bound to GDP
- 1Z5V 2.71 Å, Crystal structure of human gamma-tubulin bound to GTPgammaS
- 1Z5W 3.0 Å, Crystal Structure of gamma-tubulin bound to GTP
- 8RX1 3.57 Å, CryoEM structure of the gTuRC-CM1dim complex
- 9SMX 3.67 Å, CM1-activated gTuRC in complex with nascent alpha-E254D mutant microtubules
- 8Q62 3.72 Å, Early closed conformation of the g-tubulin ring complex
- 6V5V 3.8 Å, Structure of gamma-tubulin in the native human gamma-tubulin ring complex
- 7AS4 4.13 Å, Recombinant human gTuRC
- 6V6S 4.3 Å, Structure of the native human gamma-tubulin ring complex
- 8VA2 4.5 Å, Symmetry expanded map of 2 gamma-tubulins bound to 2 alpha tubulins in gamma tubulin…
- 9H9P 4.5 Å, Spokes 12 and 13 of the human gamma-tubulin ring complex in complex with CDK5RAP2 and…
- 9QVN 4.7 Å, Cryo-EM reconstruction of the NEDD1 anchor protein bound to the gamma-tubulin ring complex
Browse structure collections
About this viewer
MolViewer shows 7QJ5 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.