7QJB: Tubulin gamma-1 chain
Structure of recombinant human gamma-Tubulin Ring Complex 12-spoked assembly intermediate (spokes 3-14, homogeneous dataset). Determined by electron microscopy at 9.2 Å resolution. Released 26 Jan 2022.
- Method
- Electron microscopy
- Resolution
- 9.2 Å
- Organism
- Homo sapiens
- Chains
- 35
- Atoms
- 108,374
- Mol. weight
- 2626.35 kDa
- Released
- 26 Jan 2022
Explore 7QJB in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7QJB contains 606 α-helices and 280 β-strands across 35 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chains 1, 2, Q, R, S, T, U, V, W, X, Y and Z: 17 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5-9 | 5 | 1 |
| α-helix | 12-28 | 17 | |
| β-strand | 31 | 1 | 2 |
| β-strand | 37 | 1 | 2 |
| β-strand | 52-54 | 3 | 3 |
| β-strand | 60-62 | 3 | 3 |
| β-strand | 64-66 | 3 | 1 |
| α-helix | 74-78 | 5 | |
| α-helix | 81-83 | 3 | |
| α-helix | 104-113 | 10 | |
| α-helix | 115-128 | 14 | |
| β-strand | 134-138 | 5 | 1 |
| α-helix | 149-160 | 12 | |
| β-strand | 165-172 | 8 | 1 |
| α-helix | 184-197 | 14 | |
| β-strand | 201-206 | 6 | 1 |
| α-helix | 207-217 | 11 | |
| α-helix | 224-239 | 16 | |
| α-helix | 241-244 | 4 | |
| α-helix | 253-260 | 8 | |
| β-strand | 268-269 | 2 | 1 |
| β-strand | 270-273 | 4 | 4 |
| α-helix | 290-297 | 8 | |
| β-strand | 303 | 1 | 4 |
| β-strand | 317-325 | 9 | 4 |
| α-helix | 332-343 | 12 | |
| β-strand | 348 | 1 | 4 |
| β-strand | 356-361 | 6 | 4 |
| α-helix | 362-364 | 3 | |
| β-strand | 374-381 | 8 | 4 |
| α-helix | 384-401 | 18 | |
| α-helix | 409-414 | 6 | |
| α-helix | 420-439 | 20 | |
Chains a and j: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-20 | 12 | |
| α-helix | 30-39 | 10 | |
| α-helix | 51-64 | 14 | |
| α-helix | 68-84 | 17 | |
| α-helix | 90-99 | 10 | |
Chains b and i: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-34 | 22 | |
| α-helix | 41-52 | 12 | |
| α-helix | 57-67 | 11 | |
Chain c: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-14 | 11 | |
| α-helix | 33-50 | 18 | |
| α-helix | 67-79 | 13 | |
| α-helix | 83-96 | 14 | |
| α-helix | 108-114 | 7 | |
| α-helix | 154-172 | 19 | |
| α-helix | 175-182 | 8 | |
Chain C: 34 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 152-167 | 16 | |
| α-helix | 174-178 | 5 | |
| α-helix | 180-183 | 4 | |
| α-helix | 210-224 | 15 | |
| β-strand | 233-236 | 4 | 21 |
| β-strand | 245-248 | 4 | 21 |
| α-helix | 249 | 1 | |
| α-helix | 256-277 | 22 | |
| α-helix | 289-292 | 4 | |
| α-helix | 297-315 | 19 | |
| α-helix | 321-327 | 7 | |
| α-helix | 330-332 | 3 | |
| α-helix | 338-345 | 8 | |
| α-helix | 353-358 | 6 | |
| α-helix | 361-363 | 3 | |
| α-helix | 370-382 | 13 | |
| α-helix | 384-394 | 11 | |
| β-strand | 409-411 | 3 | 22 |
| β-strand | 432-434 | 3 | 22 |
| α-helix | 441-443 | 3 | |
| α-helix | 447-460 | 14 | |
| α-helix | 489-505 | 17 | |
| α-helix | 509-517 | 9 | |
| α-helix | 526-534 | 9 | |
| α-helix | 536-540 | 5 | |
| α-helix | 542 | 1 | |
| α-helix | 548-561 | 14 | |
| α-helix | 570-572 | 3 | |
| β-strand | 573-577 | 5 | 23 |
| β-strand | 616-620 | 5 | 23 |
| α-helix | 632-662 | 31 | |
| α-helix | 679-696 | 18 | |
| α-helix | 697-702 | 6 | |
| α-helix | 703-714 | 12 | |
| α-helix | 719-736 | 18 | |
| α-helix | 746-756 | 11 | |
| α-helix | 757-762 | 6 | |
| α-helix | 766-768 | 3 | |
| α-helix | 817-842 | 26 | |
| α-helix | 854-859 | 6 | |
Chain d: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 18-34 | 17 | |
| α-helix | 41-53 | 13 | |
| α-helix | 57-72 | 16 | |
Chain D: 29 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 247-259 | 13 | |
| β-strand | 266-269 | 4 | 24 |
| β-strand | 274-277 | 4 | 24 |
| α-helix | 288-310 | 23 | |
| α-helix | 318-345 | 28 | |
| α-helix | 374-387 | 14 | |
| α-helix | 393-395 | 3 | |
| α-helix | 401-403 | 3 | |
| α-helix | 409-415 | 7 | |
| α-helix | 419-429 | 11 | |
| β-strand | 448-450 | 3 | 25 |
| β-strand | 464-466 | 3 | 25 |
| α-helix | 468-470 | 3 | |
| α-helix | 477-480 | 4 | |
| α-helix | 484-495 | 12 | |
| α-helix | 534-550 | 17 | |
| α-helix | 556-565 | 10 | |
| α-helix | 571-580 | 10 | |
| α-helix | 583-586 | 4 | |
| α-helix | 589-591 | 3 | |
| α-helix | 594-607 | 14 | |
| α-helix | 615-620 | 6 | |
| β-strand | 621-623 | 3 | 26 |
| α-helix | 625-626 | 2 | |
| α-helix | 628 | 1 | |
| β-strand | 640-642 | 3 | 26 |
| α-helix | 648-650 | 3 | |
| α-helix | 654-690 | 37 | |
| α-helix | 698-721 | 24 | |
| α-helix | 722-728 | 7 | |
| α-helix | 729-740 | 12 | |
| α-helix | 750-761 | 12 | |
| α-helix | 769-810 | 42 | |
| α-helix | 827-864 | 38 | |
| α-helix | 874-880 | 7 | |
Chain e: 21 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 5-7 | 3 | |
| β-strand | 8-12 | 5 | 17 |
| β-strand | 16-21 | 6 | 17 |
| β-strand | 29-32 | 4 | 17 |
| β-strand | 38 | 1 | 18 |
| α-helix | 56-60 | 5 | |
| β-strand | 65 | 1 | 18 |
| β-strand | 71 | 1 | 19 |
| β-strand | 76 | 1 | 19 |
| α-helix | 79-88 | 10 | |
| α-helix | 89-93 | 5 | |
| α-helix | 98-100 | 3 | |
| β-strand | 103-107 | 5 | 17 |
| α-helix | 113-125 | 13 | |
| β-strand | 132-136 | 5 | 17 |
| α-helix | 137-144 | 8 | |
| β-strand | 150-155 | 6 | 20 |
| β-strand | 160-166 | 7 | 20 |
| β-strand | 169-170 | 2 | 20 |
| β-strand | 176-178 | 3 | 20 |
| α-helix | 182-196 | 15 | |
| α-helix | 203-215 | 13 | |
| α-helix | 223-232 | 10 | |
| α-helix | 251-254 | 4 | |
| α-helix | 258-261 | 4 | |
| α-helix | 264-266 | 3 | |
| α-helix | 272-273 | 2 | |
| α-helix | 274-283 | 10 | |
| α-helix | 290-294 | 5 | |
| β-strand | 297-298 | 2 | 20 |
| α-helix | 308-320 | 13 | |
| β-strand | 329 | 1 | 20 |
| α-helix | 338-346 | 9 | |
| α-helix | 351-355 | 5 | |
| β-strand | 357 | 1 | 17 |
| α-helix | 359-365 | 7 | |
| α-helix | 370-373 | 4 | |
13 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Tubulin gamma-1 chain | 1, 2, Q, R, S, T, U, V, W, X, Y, Z | protein | 451 | Homo sapiens | P23258 (AlphaFold model) |
| actin, cytoplasmic 1 | e | protein | 375 | Homo sapiens | A0A6I9HGD1 (AlphaFold model) |
| Gamma-tubulin complex component 3 | D, F, H, N, a, h, j | protein | 907 | Homo sapiens | Q96CW5 (AlphaFold model) |
| Gamma-tubulin complex component 2 | C, E, G, M | protein | 902 | Homo sapiens | Q9BSJ2 (AlphaFold model) |
| Gamma-tubulin complex component 4 | I, K | protein | 667 | Homo sapiens | Q9UGJ1 |
| Gamma-tubulin complex component 5 | J, l | protein | 1024 | Homo sapiens | Q96RT8 |
| Gamma-tubulin complex component 6 | L, c | protein | 1819 | Homo sapiens | Q96RT7 |
| Mitotic-spindle organizing protein 1 | b, d, i, k, m | protein | 82 | Homo sapiens | Q08AG7 |
Sequence of entity 1 (1, 2, Q, R, S, T, U, V, W, X, Y, Z), FASTA
>7QJB_1 Tubulin gamma-1 chain (chains 1, 2, Q, R, S, T, U, V, W, X, Y, Z)
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE
MDTSREIVQQLIDEYHAATRPDYISWGTQEQ
Sequence of entity 2 (e), FASTA
>7QJB_2 actin, cytoplasmic 1 (chains e)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF
Sequence of entity 3 (D, F, H, N, a, h, j), FASTA
>7QJB_3 Gamma-tubulin complex component 3 (chains D, F, H, N, a, h, j)
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKK
ELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQ
ALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSL
LPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTG
GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWL
HNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLES
SLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILS
LVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQS
RKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFE
TSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI
LETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHY
LRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQY
YITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFD
QIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESI
PKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTR
GRRSSHT
Sequence of entity 4 (C, E, G, M), FASTA
>7QJB_4 Gamma-tubulin complex component 2 (chains C, E, G, M)
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG
RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV
KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH
DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ
EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK
ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR
KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM
AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI
SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID
DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL
EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL
SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT
AQ
Sequence of entity 5 (I, K), FASTA
>7QJB_5 Gamma-tubulin complex component 4 (chains I, K)
MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIE
QYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSIS
HVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCH
GVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQD
LRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSIL
KNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDF
YLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEY
HGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFK
YLLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQ
FSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQN
LGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGG
TLGSFGM
Sequence of entity 6 (J, l), FASTA
>7QJB_6 Gamma-tubulin complex component 5 (chains J, l)
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHK
IEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDS
PSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSRE
DSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHS
NLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNI
IVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRT
YQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGV
AEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWI
VHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQG
PSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESV
QSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDF
HEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYL
QAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSIS
FENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDV
LLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNY
IMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAG
MEQS
Sequence of entity 7 (L, c), FASTA
>7QJB_7 Gamma-tubulin complex component 6 (chains L, c)
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPD
MSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGS
GPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQ
VMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNAD
LSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERV
GCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVL
IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLD
SLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVG
AVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWV
YSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGK
TINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEE
KELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERR
QAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALW
RIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGG
QGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFL
PVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPA
VATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQ
PTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTH
GHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNA
SIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGE
SVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVV
STRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPR
LPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDL
SPNWPLNSQEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSE
PPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVN
KAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNS
VLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGC
VSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVI
QGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSI
FSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQ
PHLEDFLLRINFNNYYQDA
Sequence of entity 8 (b, d, i, k, m), FASTA
>7QJB_8 Mitotic-spindle organizing protein 1 (chains b, d, i, k, m)
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEAL
SSVIKELRKATEALKAAENMTS
Primary citation
Modular assembly of the principal microtubule nucleator gamma-TuRC. Wurtz, M., Zupa, E., Atorino, E.S. et al. Nat Commun (2022) 13:473-473. DOI 10.1038/s41467-022-28079-0 · PubMed
Other PDB entries of the same protein (UniProt P23258 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 3CB2 2.3 Å, Crystal structure of human gamma-tubulin bound to GDP
- 1Z5V 2.71 Å, Crystal structure of human gamma-tubulin bound to GTPgammaS
- 1Z5W 3.0 Å, Crystal Structure of gamma-tubulin bound to GTP
- 8RX1 3.57 Å, CryoEM structure of the gTuRC-CM1dim complex
- 9SMX 3.67 Å, CM1-activated gTuRC in complex with nascent alpha-E254D mutant microtubules
- 8Q62 3.72 Å, Early closed conformation of the g-tubulin ring complex
- 6V5V 3.8 Å, Structure of gamma-tubulin in the native human gamma-tubulin ring complex
- 7AS4 4.13 Å, Recombinant human gTuRC
- 6V6S 4.3 Å, Structure of the native human gamma-tubulin ring complex
- 8VA2 4.5 Å, Symmetry expanded map of 2 gamma-tubulins bound to 2 alpha tubulins in gamma tubulin…
- 9H9P 4.5 Å, Spokes 12 and 13 of the human gamma-tubulin ring complex in complex with CDK5RAP2 and…
- 9QVN 4.7 Å, Cryo-EM reconstruction of the NEDD1 anchor protein bound to the gamma-tubulin ring complex
Browse structure collections
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