Crystal structure of RPA70N-BLMp2 fusion. Determined by X-ray diffraction at 1.8 Å resolution. Released 14 Jun 2023.
Explore 7XUW in 3D Show helices and sheets RCSB PDB PDBe
7XUW contains 7 α-helices and 8 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 9-11 | 3 | |
| α-helix | 12-16 | 5 | |
| β-strand | 24-32 | 9 | 1 |
| β-strand | 42-47 | 6 | 1 |
| β-strand | 51-58 | 8 | 1 |
| α-helix | 60-62 | 3 | |
| α-helix | 63-67 | 5 | |
| β-strand | 76-86 | 11 | 1 |
| β-strand | 92-103 | 12 | 1 |
| α-helix | 105-108 | 4 | |
| β-strand | 116-117 | 2 | 1 |
| β-strand | 121 | 1 | 2 |
| α-helix | 550 | 1 | |
| β-strand | 551 | 1 | 2 |
| α-helix | 552-553 | 2 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein | A | protein | 146 | Homo sapiens | P27694 (AlphaFold model), P54132 (AlphaFold model) |
>7XUW_1 fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein (chains A) MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLAT QLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVLKSAEAVGVKIGNPVPYNE GTSSGSYDIDNFDIDDFDDDDDWEDI
Structural characterization of human RPA70N association with DNA damage response proteins. Wu, Y., Fu, W., Zang, N. et al. Elife (2023) 12. DOI 10.7554/eLife.81639 · PubMed
Other PDB entries of the same protein (UniProt P27694 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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