9T63: Inactive protein-arginine deiminase type-6

Asymmetric unit of a cytoplasmic lattice filament repeat unit. Determined by electron microscopy at 4.7 Å resolution. Released 12 Aug 2026.

Method: Electron microscopy
Resolution: 4.7 Å
Organism: Mus musculus
Chains: 29
Atoms: 76,879
Mol. weight: 1923.77 kDa
Released: 12 Aug 2026

Explore 9T63 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9T63 contains 683 α-helices and 938 β-strands across 29 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain a: 33 helices, 44 β-strands

Element	Residues	Length	Sheet
β-strand	3-7	5	212
β-strand	13-16	4	212
β-strand	24	1	213
α-helix	25-36	12
α-helix	40-42	3
β-strand	43-47	5	212
β-strand	50-51	2	212
α-helix	52	1
β-strand	57	1	213
α-helix	58-61	4
β-strand	68-73	6	212
β-strand	124-126	3	214
β-strand	135-140	6	214
β-strand	147-157	11	214
α-helix	170-171	2
α-helix	175-177	3
β-strand	178-184	7	214
α-helix	188-190	3
β-strand	193-196	4	214
α-helix	197-199	3
β-strand	200-202	3	214
α-helix	203-204	2
β-strand	207	1	214
α-helix	210-212	3
β-strand	218-223	6	214
β-strand	233-239	7	214
β-strand	243-244	2	215
β-strand	249-250	2	215
β-strand	251-256	6	214
α-helix	258-260	3
β-strand	262-268	7	214
α-helix	271-273	3
β-strand	275	1	214
β-strand	286-287	2	214
α-helix	300-302	3
β-strand	323	1	216
α-helix	332-334	3
β-strand	335-337	3	216
β-strand	344-346	3	216
α-helix	425-426	2
β-strand	433-435	3	217
α-helix	438-444	7
β-strand	454-457	4	217
β-strand	461-467	7	217
β-strand	475-477	3	218
β-strand	480-484	5	218
β-strand	489	1	219
β-strand	500	1	219
α-helix	508-516	9
β-strand	526	1	220
α-helix	531-533	3
α-helix	535-536	2
β-strand	537	1	218
β-strand	538-542	5	217
α-helix	543-547	5
β-strand	557-559	3	217
β-strand	563-572	10	218
β-strand	578-586	9	218
α-helix	591-592	2
α-helix	596-605	10
α-helix	615-627	13
α-helix	668-671	4
α-helix	672-680	9
α-helix	685-697	13
α-helix	700-711	12
β-strand	712	1	221
β-strand	719	1	221
β-strand	723-725	3	222
β-strand	731-733	3	222
α-helix	734-742	9
β-strand	747	1	223
α-helix	753	1
β-strand	754	1	223
α-helix	755-756	2
α-helix	760-763	4
α-helix	765-774	10
α-helix	778-781	4

Chain A: 29 helices, 51 β-strands

Element	Residues	Length	Sheet
β-strand	3	1	1
β-strand	6-8	3	2
β-strand	15-20	6	1
β-strand	21	1	2
β-strand	24-28	5	2
β-strand	39-43	5	1
β-strand	48-52	5	2
β-strand	55-57	3	2
α-helix	59-61	3
β-strand	64-68	5	1
β-strand	74-79	6	2
β-strand	89-97	9	1
β-strand	100-114	15	1
β-strand	115-119	5	3
α-helix	134-138	5
β-strand	149-151	3	4
α-helix	152	1
β-strand	153	1	3
α-helix	154	1
α-helix	165-169	5
α-helix	175-177	3
β-strand	179-186	8	3
α-helix	189-194	6
β-strand	195-200	6	4
α-helix	203-208	6
β-strand	209-213	5	3
β-strand	222-225	4	3
β-strand	226	1	5
β-strand	229	1	5
β-strand	231-233	3	4
α-helix	234-236	3
β-strand	242-249	8	3
β-strand	254	1	6
β-strand	257	1	6
β-strand	260-269	10	4
β-strand	279-290	12	4
α-helix	291-293	3
β-strand	294-295	2	7
α-helix	301	1
β-strand	302-308	7	8
α-helix	311-313	3
α-helix	314-327	14
β-strand	331-332	2	8
α-helix	344-348	5
β-strand	349-355	7	7
β-strand	360-366	7	7
α-helix	377-381	5
α-helix	383	1
β-strand	387-390	4	7
α-helix	404-406	3
β-strand	408-409	2	9
β-strand	413-415	3	10
β-strand	418-420	3	10
β-strand	425-429	5	9
β-strand	439	1	9
α-helix	442-449	8
β-strand	457-460	4	9
β-strand	464	1	11
α-helix	469-471	3
β-strand	473-477	5	12
β-strand	488-492	5	12
α-helix	495-505	11
α-helix	506-510	5
β-strand	514	1	13
α-helix	521-527	7
β-strand	533	1	13
α-helix	534-539	6
α-helix	541-565	25
β-strand	572-574	3	12
β-strand	579-582	4	11
α-helix	589-591	3
β-strand	597-600	4	11
β-strand	609-611	3	14
β-strand	614-618	5	14
α-helix	630-642	13
β-strand	645-649	5	14
α-helix	652-656	5
β-strand	665-670	6	8
α-helix	671-673	3
α-helix	677-679	3

Chain b: 8 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	2-15	14
α-helix	17-18	2
β-strand	21-25	5	206
β-strand	32-38	7	206
β-strand	49-55	7	206
α-helix	64-65	2
β-strand	66-69	4	206
β-strand	78	1	207
β-strand	84	1	207
α-helix	87-89	3
α-helix	99-111	13
α-helix	121-129	9
α-helix	131-141	11
α-helix	142-146	5

Chain B: 26 helices, 57 β-strands

Element	Residues	Length	Sheet
β-strand	3	1	19
β-strand	6-8	3	20
β-strand	15-20	6	19
β-strand	21	1	20
β-strand	24-28	5	20
β-strand	39-44	6	19
β-strand	48-52	5	20
β-strand	55-58	4	20
β-strand	65-68	4	19
β-strand	74-79	6	20
β-strand	89-96	8	19
β-strand	106-114	9	19
β-strand	115-119	5	21
α-helix	134-137	4
β-strand	149-151	3	22
β-strand	153	1	21
α-helix	166-168	3
β-strand	170	1	21
α-helix	175-177	3
β-strand	179-186	8	21
α-helix	189-194	6
β-strand	195-200	6	22
α-helix	203-208	6
β-strand	209-213	5	21
β-strand	222-225	4	21
β-strand	226	1	23
β-strand	229	1	23
β-strand	231-233	3	22
β-strand	242-249	8	21
β-strand	254	1	24
β-strand	257	1	24
β-strand	260-269	10	22
β-strand	279-290	12	22
α-helix	291-293	3
β-strand	294	1	25
α-helix	301	1
β-strand	302-308	7	26
α-helix	315-326	12
β-strand	331-334	4	26
α-helix	344-347	4
β-strand	349-356	8	25
β-strand	359-366	8	25
α-helix	378-381	4
α-helix	383	1
β-strand	387-390	4	25
α-helix	404-406	3
β-strand	408-409	2	27
β-strand	413-415	3	28
β-strand	418-420	3	28
β-strand	425-426	2	27
β-strand	427-429	3	29
β-strand	439	1	29
α-helix	442-449	8
β-strand	458-460	3	29
β-strand	464	1	30
α-helix	469-471	3
β-strand	473-477	5	31
β-strand	488-493	6	31
α-helix	495-505	11
α-helix	506-510	5
β-strand	514	1	32
α-helix	521-526	6
β-strand	533	1	32
α-helix	534-539	6
α-helix	541-565	25
α-helix	569-571	3
β-strand	572-575	4	31
β-strand	579-582	4	30
α-helix	589-591	3
β-strand	597-600	4	30
β-strand	609-611	3	33
β-strand	614-616	3	33
β-strand	617-618	2	34
β-strand	624	1	35
β-strand	629	1	35
α-helix	630-642	13
β-strand	645	1	33
β-strand	648-649	2	34
α-helix	652-656	5
α-helix	657-658	2
β-strand	666-670	5	26
α-helix	671-673	3
α-helix	677-679	3

Chain c: 26 helices, 18 β-strands

Element	Residues	Length	Sheet
β-strand	5-8	4	254
α-helix	11-28	18
α-helix	38-40	3
α-helix	49-51	3
β-strand	53-55	3	255
β-strand	61-63	3	255
β-strand	65-69	5	254
α-helix	73-80	8
α-helix	82-86	5
α-helix	89-91	3
β-strand	92-94	3	254
α-helix	103-104	2
α-helix	105-110	6
α-helix	111-128	18
β-strand	134-138	5	254
α-helix	144-160	17
β-strand	165-169	5	254
β-strand	172	1	256
α-helix	183-195	13
β-strand	200-202	3	254
β-strand	205	1	256
α-helix	206-217	12
α-helix	224-243	20
α-helix	252-259	8
α-helix	263-265	3
β-strand	269-273	5	257
β-strand	277	1	258
α-helix	281-283	3
α-helix	288-295	8
α-helix	298-300	3
β-strand	301	1	257
α-helix	307-309	3
β-strand	312-321	10	257
α-helix	325-338	14
β-strand	343	1	257
β-strand	351-356	6	257
α-helix	359-360	2
β-strand	368	1	258
α-helix	369-370	2
β-strand	373-381	9	257
α-helix	382-384	3
α-helix	385-400	16
α-helix	406-409	4
α-helix	415-436	22

Chain C: 26 helices, 57 β-strands

Element	Residues	Length	Sheet
β-strand	6-8	3	46
β-strand	15-20	6	47
β-strand	21	1	46
β-strand	24-28	5	46
β-strand	39-44	6	47
β-strand	48-52	5	46
β-strand	55-58	4	46
β-strand	65-68	4	47
β-strand	74-79	6	46
β-strand	89-97	9	47
β-strand	100-114	15	47
β-strand	115-119	5	48
α-helix	134-138	5
β-strand	141	1	49
β-strand	147	1	49
β-strand	149-151	3	50
β-strand	153	1	48
α-helix	166-169	4
α-helix	171-172	2
α-helix	175-177	3
β-strand	179-186	8	48
α-helix	189-194	6
β-strand	195-200	6	50
α-helix	203-208	6
β-strand	209-213	5	48
β-strand	222-225	4	48
β-strand	226	1	51
β-strand	229	1	51
β-strand	231-233	3	50
β-strand	242-249	8	48
β-strand	254	1	52
β-strand	257	1	52
β-strand	260-269	10	50
β-strand	273	1	53
β-strand	276	1	53
β-strand	279-290	12	50
β-strand	294	1	54
α-helix	301	1
β-strand	302-308	7	55
α-helix	315-326	12
β-strand	330-334	5	55
α-helix	341	1
α-helix	344-348	5
β-strand	349-355	7	54
β-strand	360-366	7	54
α-helix	378-381	4
α-helix	383	1
β-strand	387-390	4	54
α-helix	404-406	3
β-strand	407-409	3	56
β-strand	413-415	3	57
β-strand	418-420	3	57
β-strand	425-427	3	56
β-strand	429	1	58
β-strand	439	1	58
α-helix	442-449	8
β-strand	457-458	2	56
β-strand	464	1	59
α-helix	469-471	3
β-strand	473-477	5	60
β-strand	488-494	7	60
α-helix	495-505	11
α-helix	506-510	5
β-strand	514	1	61
α-helix	521-527	7
β-strand	533	1	61
α-helix	534-539	6
α-helix	541-565	25
β-strand	572-576	5	60
β-strand	579-583	5	59
α-helix	589-591	3
β-strand	596-600	5	59
β-strand	609-611	3	62
β-strand	614-618	5	62
β-strand	624-625	2	63
β-strand	628-629	2	63
α-helix	630-642	13
β-strand	645-649	5	62
α-helix	652-656	5
α-helix	657-658	2
β-strand	666-670	5	55
α-helix	671-673	3
α-helix	677-679	3

Chain d: 27 helices, 18 β-strands

Element	Residues	Length	Sheet
β-strand	2-8	7	15
α-helix	11-28	18
β-strand	30	1	16
β-strand	35	1	17
β-strand	36	1	16
α-helix	41-45	5
α-helix	47-49	3
β-strand	51-54	4	17
β-strand	58-61	4	17
β-strand	63-67	5	15
α-helix	70-78	9
α-helix	82-84	3
α-helix	87-89	3
β-strand	90-92	3	15
α-helix	101-102	2
α-helix	103-107	5
α-helix	109-125	17
β-strand	129-138	10	15
α-helix	143-147	5
α-helix	148-158	11
β-strand	164-170	7	15
α-helix	181-195	15
β-strand	198-203	6	15
α-helix	204-209	6
α-helix	210-214	5
α-helix	222-241	20
α-helix	250-257	8
β-strand	265-266	2	15
β-strand	267-271	5	18
α-helix	283-285	3
α-helix	286-293	8
α-helix	296-298	3
β-strand	299	1	18
α-helix	305-307	3
β-strand	310-318	9	18
α-helix	323-336	14
α-helix	338-340	3
β-strand	341	1	18
β-strand	349-354	6	18
α-helix	357-358	2
β-strand	364-371	8	18
α-helix	372-374	3
α-helix	375-390	16
α-helix	395-401	7
α-helix	405-427	23

Chain D: 29 helices, 57 β-strands

Element	Residues	Length	Sheet
β-strand	6-8	3	74
β-strand	15-16	2	75
β-strand	19-20	2	76
β-strand	25-28	4	74
β-strand	39-42	4	75
β-strand	48-52	5	74
β-strand	55-57	3	74
α-helix	59-61	3
β-strand	67-68	2	75
β-strand	74-79	6	74
β-strand	89-96	8	75
β-strand	97	1	77
β-strand	100	1	77
β-strand	106-111	6	75
β-strand	113-114	2	76
β-strand	115-119	5	78
α-helix	134-137	4
β-strand	149-151	3	79
β-strand	153	1	78
α-helix	157-159	3
α-helix	165-168	4
α-helix	171-172	2
α-helix	175-177	3
β-strand	179-186	8	78
α-helix	189-194	6
β-strand	195-200	6	79
α-helix	203-208	6
β-strand	209-212	4	78
β-strand	223-225	3	78
β-strand	226	1	80
β-strand	229	1	80
β-strand	231-233	3	79
α-helix	234-236	3
β-strand	242-249	8	78
β-strand	254	1	81
β-strand	257	1	81
β-strand	260-269	10	79
β-strand	273	1	82
β-strand	276	1	82
β-strand	279-280	2	79
β-strand	284-290	7	79
β-strand	294-295	2	83
α-helix	296-297	2
α-helix	301	1
β-strand	302-308	7	84
α-helix	314-327	14
β-strand	330-334	5	84
α-helix	344-347	4
β-strand	349-355	7	83
β-strand	360-366	7	83
α-helix	378-381	4
α-helix	383	1
β-strand	386-390	5	83
α-helix	404-406	3
β-strand	407-409	3	85
β-strand	413-415	3	86
β-strand	418-420	3	86
β-strand	425-429	5	85
α-helix	442-449	8
β-strand	456-460	5	85
β-strand	464	1	87
α-helix	469-471	3
β-strand	473-477	5	88
β-strand	488-493	6	88
α-helix	495-507	13
α-helix	509-512	4
β-strand	514	1	89
α-helix	521-526	6
β-strand	533	1	89
α-helix	534-539	6
α-helix	541-565	25
β-strand	572-575	4	88
β-strand	579-582	4	87
α-helix	589-591	3
β-strand	597-600	4	87
β-strand	609-611	3	90
β-strand	614-618	5	90
β-strand	624-625	2	91
β-strand	628-629	2	91
α-helix	630-642	13
β-strand	645-649	5	90
α-helix	652-656	5
α-helix	657-658	2
β-strand	665-670	6	84
α-helix	671-673	3
α-helix	677-679	3

21 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Inactive protein-arginine deiminase type-6	A, B, C, D, E, F, G, H, I, J	protein	682	Mus musculus	Q8K3V4 (AlphaFold model)
Oocyte-expressed protein homolog	O, R	protein	164	Mus musculus	Q9CWE6 (AlphaFold model)
KH domain-containing protein 3	S	protein	440	Mus musculus	Q9CWU5 (AlphaFold model)
NLR family, pyrin domain containing 4F	X, Y	protein	937	Mus musculus	L7N1W9 (AlphaFold model)
NACHT, LRR and PYD domains-containing protein 14	Z	protein	993	Mus musculus	Q6B966
Ubiquitin-conjugating enzyme E2 D3	b	protein	147	Mus musculus	P61079
S-phase kinase-associated protein 1	f, h	protein	163	Mus musculus	Q9WTX5
Zinc finger BED domain-containing protein 3	T	protein	228	Mus musculus	Q9D0L1
E3 ubiquitin-protein ligase UHRF1	a	protein	782	Mus musculus	Q8VDF2
NACHT, LRR and PYD domains-containing protein 5	M, P	protein	1163	Mus musculus	Q9R1M5
Transducin-like enhancer protein 6	N, Q	protein	581	Mus musculus	Q9WVB3
Tubulin alpha-1C chain	c	protein	449	Mus musculus	P68373

2 more molecules are not listed.

Sequence of entity 1 (A, B, C, D, E, F, G, H, I, J), FASTA

>9T63_1 Inactive protein-arginine deiminase type-6 (chains A, B, C, D, E, F, G, H, I, J)
MSFQNSLSLSLVNPTHALCMVGMEITLDISKCAPDKCKSFTIRGSPRILIHISSSVIAGK
EDTVVWRSMNHPTVALVRMVAPSPTVDEDKVLVSYFCPDQEVPTATAVLFLTGIEISLEA
DIYRDGQLDMPSDKQAKKKWMWGMNGWGAILLVNCSPNAVGQPDEQSFQEGPREIQNLSQ
MNVTVEGPTSILQNYQLILHTSEEEAKKTRVYWSQRGSSAYELVVGPNKPVYLLPTFENR
RKEAFYVEATEFPSPSFSGLISLSLSLVEKAHDECIPEIPLYKDTVMFRVAPYIFMPSTQ
MPLEVYLCRELQLQGFVDSVTKLSEKSKVQVVKVYEDPNRQSKWLQDEMAFCYTQAPHKT
VSLILDTPRVSKLEDFPMKYTLTPGSGYLIRQTEDHRVASLDSIGNLMVSPPVKAQGKDY
PLGRVLIGGSFYPSSEGRDMNKGLREFVYAQQVQAPVELFSDWLMTGHMDQFMCFVPTND
KNNDQKDFRLLLASPSACFELFEQKQKEGYGNVTLFEDIGAEQLLSNGRESKTISQILAD
KSFREQNTYVEKCISLNRTLLKTELGLEDKDIILIPQLFCLEQLTNVPSNQQSTKLFARP
YFPDMLQIIVLGKNLGIPKPFGPKINGTCCLEEKVCGLLEPLGLKCTFIDDFDCYLANIG
DVCASAIINRVPFAFKWWKMTP

Sequence of entity 2 (O, R), FASTA

>9T63_2 Oocyte-expressed protein homolog (chains O, R)
MASHTADADAKPDSDSQKLLNVLPVSLRLRTRPWWFPIQEVSNPLVLYMEAWVAERVIGT
DQAEISEIEWMCQALLTVDSVNSGNLAEITIFGQPSAQTRMKNILLNMAAWHKENELQRA
VKVKEVEEFLKIRASSILSKLSKKGLKLAGFPLPLEGRETQMES

Sequence of entity 3 (S), FASTA

>9T63_3 KH domain-containing protein 3 (chains S)
MASLKRFQTLVPLDHKQGTLFEIIGEPKLPKWFHVECLEDPKRLYVEPRLLEIMFGKDGE
HIPHLESMLHTLIHVNVWGPERRAEIWIFGPPPFRRDVDRMLTDLAHYCRMKLMEIEALE
AGVERRRMAAHKAATQPAPVKVREAAPRPASVKVPETATQPAPVKVREAAPQPAPVQEVR
EAAPQQASVQEEVREAATEQAPVQEVREAATEQAPVQEVSEAATEQAPVQEVNEAATEQA
SVQAVREAATRPAPGKVRKAATQPAPVQVCQEATQLAPVKVREAATQPASGKVREAATQL
APVKVRKAATQLAPVKVHEAATQPAPGKVSDAATQSASVQVREAATQLSPVEATDTSQLA
QVKADEAFAQHTSGEAHQVANGQSPIEVCETATGQHSLDVSRALSQKCPEVFEWETQSCL
DGSYVIVQPPRDAWESFIIL

Sequence of entity 4 (X, Y), FASTA

>9T63_4 NLR family, pyrin domain containing 4F (chains X, Y)
MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLK
CGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDF
IKETFIQNDYDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKF
SYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTK
QESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAF
DERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPV
SLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRN
GIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIET
VLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAE
LQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLS
FSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYP
SFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEK
LMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVLS
NCSLSEQCWDYLSEVLRQNKTLSHLDISSNDLKDEGLKILCRSLILPYCVLESLCLSCCG
ITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITD
ASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRF

Sequence of entity 5 (Z), FASTA

>9T63_5 NACHT, LRR and PYD domains-containing protein 14 (chains Z)
MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITP
KDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLN
GKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCK
DWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMD
YIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTST
ALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDI
LLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLES
NHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQL
RFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARA
DLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELS
HPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCK
LRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLER
LALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVL
RSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSC
VLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLT
PGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKK
IKKFLVDVRINNPHLVIGPECPNTESGCWWNYF

Sequence of entity 6 (b), FASTA

>9T63_6 Ubiquitin-conjugating enzyme E2 D3 (chains b)
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY
PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV
PEIARIYKTDRDKYNRISREWTQKYAM

Sequence of entity 7 (f, h), FASTA

>9T63_7 S-phase kinase-associated protein 1 (chains f, h)
MPTIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQ
WCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTC
KTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK

Sequence of entity 8 (T), FASTA

>9T63_8 Zinc finger BED domain-containing protein 3 (chains T)
MKSKKPLKITMEDSRRLNDPAEQGGLCPAPVGPSYSEAWGYFHLDPAQPRHRMMSAWATC
RLCGLQVGGLPNFQMWTRALCQHLSDVHLPELKKSAAPSSPTTMPCPPPPSPTMAAEGDW
ARLLEQMGELAMRGSQRELELERREAALMQAELELERKRQALKQEAQSVEQERHQLQVER
EALSKWIKKQSPGAQVPEPPSPLPLLPKEDPDIHDNNSDNDMVTKVLL

Sequence of entity 9 (a), FASTA

>9T63_9 E3 ubiquitin-protein ligase UHRF1 (chains a)
MWIQVRTMDGKETHTVNSLSRLTKVQELRKKIEEVFHVEPQLQRLFYRGKQMEDGHTLFD
YDVRLNDTIQLLVRQSLALPLSTKERDSELSDSDSGYGVGHSESDKSSTHGEGAAEADDK
TVWEDTDLGLYKVNEYVDVRDNIFGAWFEAQVVQVQKRALSEDEPCSSSAVKTSEDDIMY
HVKYDDYPEHGVDIVKAKNVRARARTVIPWENLEVGQVVMANYNVDYPRKRGFWYDVEIC
RKRQTRTARELYGNIRLLNDSQLNNCRIMFVDEVLMIELPKERRPLIASPSQPPPALRNT
GKSGPSCRFCKDDENKPCRKCACHVCGGREAPEKQLLCDECDMAFHLYCLKPPLTSVPPE
PEWYCPSCRTDSSEVVQAGEKLKESKKKAKMASATSSSRRDWGKGMACVGRTTECTIVPA
NHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNY
FTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVV
RNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKD
RTRQLGLTMQYPEGYLEALANKEKSRKRPAKALEQGPSSSKTGKSKQKSTGPTLSSPRAS
KKSKLEPYTLSEQQANLIKEDKGNAKLWDDVLTSLQDGPYQIFLSKVKEAFQCICCQELV
FRPVTTVCQHNVCKDCLDRSFRAQVFSCPACRFELDHSSPTRVNQPLQTILNQLFPGYGS
GR

Sequence of entity 10 (M, P), FASTA

>9T63_10 NACHT, LRR and PYD domains-containing protein 5 (chains M, P)
MGPPEKESKAILKARGLEEEQKSERKMTSPENDSKSIQKDQGPEQEQTSESTMGPPEKES
KAILKARGLEEEQKSERKMTSPENDSKSIQKDQGPEQEQTSESTMGPPEKDSKAILKARG
LEEEQKSESTMSPSENVSRAILKDSGSEEVEQASERKMTSPENDSKSIQKDQGPEQEQTS
ETLQSKEEDEVTEADKDNGGDLQDYKAHVIAKFDTSVDLHYDSPEMKLLSDAFKPYQKTF
QPHTIILHGRPGVGKSALARSIVLGWAQGKLFQKMSFVIFFSVREIKWTEKSSLAQLIAK
ECPDSWDLVTKIMSQPERLLFVIDGLDDMDSVLQHDDMTLSRDWKDEQPIYILMYSLLRK
ALLPQSFLIITTRNTGLEKLKSMVVSPLYILVEGLSASRRSQLVLENISNESDRIQVFHS
LIENHQLFDQCQAPSVCSLVCEALQLQKKLGKRCTLPCQTLTGLYATLVFHQLTLKRPSQ
SALSQEEQITLVGLCMMAAEGVWTMRSVFYDDDLKNYSLKESEILALFHMNILLQVGHNS
EQCYVFSHLSLQDFFAALYYVLEGLEEWNQHFCFIENQRSIMEVKRTDDTRLLGMKRFLF
GLMNKDILKTLEVLFEYPVIPTVEQKLQHWVSLIAQQVNGTSPMDTLDAFYCLFESQDEE
FVGGALKRFQEVWLLINQKMDLKVSSYCLKHCQNLKAIRVDIRDLLSVDNTLELCPVVTV
QETQCKPLLMEWWGNFCSVLGSLRNLKELDLGDSILSQRAMKILCLELRNQSCRIQKLTF
KSAEVVSGLKHLWKLLFSNQNLKYLNLGNTPMKDDDMKLACEALKHPKCSVETLRLDSCE
LTIIGYEMISTLLISTTRLKCLSLAKNRVGVKSMISLGNALSSSMCLLQKLILDNCGLTP
ASCHLLVSALFSNQNLTHLCLSNNSLGTEGVQQLCQFLRNPECALQRLILNHCNIVDDAY
GFLAMRLANNTKLTHLSLTMNPVGDGAMKLLCEALKEPTCYLQELELVDCQLTQNCCEDL
ACMITTTKHLKSLDLGNNALGDKGVITLCEGLKQSSSSLRRLGLGACKLTSNCCEALSLA
ISCNPHLNSLNLVKNDFSTSGMLKLCSAFQCPVSNLGIIGLWKQEYYARVRRQLEEVEFV
KPHVVIDGDWYASDEDDRNWWKN

Sequence of entity 11 (N, Q), FASTA

>9T63_11 Transducin-like enhancer protein 6 (chains N, Q)
MTSHRQSSDTFGGILPSTLSSRYLSIVNQLPEEFSSVVSEMMVHLENIFSLAENFFQAIE
RFSRTPDLLERNKMSIGVGAEGDSWPCHVSHEAPMGSAQTTENSAKEEDKQVPESAALQH
PKFKSTPGPQLPTRRRFLSESDELQDPQPVWDAEPQFCQGFLIQGLWELFMDSRQKNQQE
HGGEDSSQESKDSGLCDFKPEPQPRHRNSLSDSADPFLIKSPSALLDYYQEDVSRPQPET
QESSGRADKFLKPLSWGSEVLESSCNQPSTALWQLERFTVPQALQKVRVLKHQELLLVVA
VSSFTRHVFTCSQSGIKVWNLVNQVAEDRDPESHLKCSVQDNKVYLRTCLLSSNSRTLFA
GGYNLPGVIVWDLAAPSLYEKCQLPCEGLSCQALANTKENMALAGFTDGTVRIWDLRTQE
IVRNLKGPTNSARNLVVKDDNIWTGGLDACLRCWDLRMAKVSLEHLFQSQIMSLAHSPTE
DWLLLGLANGQHCLFNSRKRDQVLTVDTKDNTILGLKFSPNGKWWASVGMGNFITVHSMP
TGAKLFQVPEVGPVRCFDMTENGRLIITGSRDCASVYHIKY

Sequence of entity 12 (c), FASTA

>9T63_12 Tubulin alpha-1C chain (chains c)
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGADSAEGDDEGEEY

Primary citation

In-situ cryo-ET of mouse embryos reveals cytoplasmic lattices contain ubiquitin-charged E2-E3 ligase assemblies. Singh, K., Harasimov, K., Niakan, K.K. et al. EMBO J (2026). DOI 10.1038/s44318-026-00895-w · PubMed

Other PDB entries of the same protein (UniProt Q8K3V4 (AlphaFold model), which also has an AlphaFold model), best resolution first:

24MC 3.4 Å, Structure of oocyte cytoplasmic lattices
12DL 3.5 Å, Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs
9XRL 3.74 Å, Structure of mouse cytoplasmic lattice (CPL) repeating unit
9SFP 4.2 Å, Native cytoplasmic lattices from mouse oocytes
9W2M 4.2 Å, Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte
9T66 5.3 Å, Complex linking two repeat units of a cytoplasmic lattice filament
9T65 5.6 Å, Complex linking two cytoplasmic lattice filaments
9T64 7.3 Å, Cytoplasmic lattice filament repeat unit with the central FBXW-SKP1 complex
9T67 7.7 Å, Cytoplasmic lattice filament repeat unit with ubiquitin
9T68 8.0 Å, Composite structure of the repeat unit of cytoplasmic lattice filament

Browse structure collections

About this viewer

MolViewer shows 9T63 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.