4N5U: Receptor-type tyrosine-protein phosphatase F

Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]. Determined by X-ray diffraction at 1.46 Å resolution. Released 30 Oct 2013.

Method
X-ray diffraction
Resolution
1.46 Å
Organism
Homo sapiens
Chains
1
Atoms
1,015
Mol. weight
13.1 kDa
Released
30 Oct 2013

Explore 4N5U in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4N5U contains 4 α-helices and 8 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 4 helices, 8 β-strands

ElementResiduesLengthSheet
β-strand611-61991
β-strand622-62871
α-helix629-6313
α-helix632-6343
β-strand639-648102
β-strand657-66372
β-strand668-67141
α-helix674-6752
β-strand679-688102
β-strand692-69542
α-helix696-6983
β-strand699-70242

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Receptor-type tyrosine-protein phosphatase FAprotein117Homo sapiensP10586 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>4N5U_1 Receptor-type tyrosine-protein phosphatase F (chains A)
QDYGGTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRG
RHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEAENLYFQ

Primary citation

Crystal structure of the 4th FN3 domain of human PTP, receptor F [PSI-NYSGRC-006240]. Kumar, P.R., Casadevall, A., Almo, S.C. To be published.

Other PDB entries of the same protein (UniProt P10586 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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