5IJN: Nuclear pore complex protein NUP155
Composite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205). Determined by electron microscopy at 21.4 Å resolution. Released 27 Apr 2016.
- Method
- Electron microscopy
- Resolution
- 21.4 Å
- Organism
- Homo sapiens
- Chains
- 26
- Atoms
- 74,288
- Mol. weight
- 2898.12 kDa
- Released
- 27 Apr 2016
Explore 5IJN in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
5IJN contains 730 α-helices and 295 β-strands across 26 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chains A and B: 21 helices, 38 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-39 | 18 | |
| α-helix | 46-49 | 4 | |
| β-strand | 63-64 | 2 | 1 |
| β-strand | 81-88 | 8 | 2 |
| α-helix | 89-90 | 2 | |
| α-helix | 91-95 | 5 | |
| β-strand | 104-109 | 6 | 3 |
| β-strand | 114-119 | 6 | 3 |
| β-strand | 122-127 | 6 | 3 |
| β-strand | 134-137 | 4 | 3 |
| β-strand | 146-150 | 5 | 4 |
| α-helix | 151-153 | 3 | |
| β-strand | 163-168 | 6 | 4 |
| β-strand | 172-180 | 9 | 4 |
| β-strand | 198-202 | 5 | 4 |
| β-strand | 208-209 | 2 | 4 |
| β-strand | 215-220 | 6 | 5 |
| β-strand | 226-230 | 5 | 5 |
| β-strand | 236-238 | 3 | 5 |
| β-strand | 255-256 | 2 | 5 |
| β-strand | 279-285 | 7 | 6 |
| β-strand | 290-295 | 6 | 6 |
| β-strand | 300-306 | 7 | 6 |
| β-strand | 309-311 | 3 | 6 |
| β-strand | 317-318 | 2 | 6 |
| α-helix | 320-327 | 8 | |
| β-strand | 344-347 | 4 | 7 |
| β-strand | 356-361 | 6 | 7 |
| β-strand | 367-371 | 5 | 7 |
| β-strand | 375 | 1 | 8 |
| β-strand | 381 | 1 | 8 |
| β-strand | 386-391 | 6 | 7 |
| β-strand | 406 | 1 | 1 |
| β-strand | 411-413 | 3 | 1 |
| β-strand | 417-423 | 7 | 1 |
| β-strand | 429-436 | 8 | 1 |
| β-strand | 447-452 | 6 | 1 |
| β-strand | 460-463 | 4 | 2 |
| α-helix | 496-498 | 3 | |
| β-strand | 499-503 | 5 | 2 |
| β-strand | 507-513 | 7 | 2 |
| α-helix | 514-515 | 2 | |
| α-helix | 516-522 | 7 | |
| α-helix | 536-542 | 7 | |
| α-helix | 544-556 | 13 | |
| α-helix | 564-576 | 13 | |
| α-helix | 661-679 | 19 | |
| β-strand | 681 | 1 | 9 |
| β-strand | 683 | 1 | 10 |
| β-strand | 700 | 1 | 10 |
| α-helix | 704-723 | 20 | |
| α-helix | 725-728 | 4 | |
| α-helix | 770-800 | 31 | |
| α-helix | 803-810 | 8 | |
| α-helix | 815-819 | 5 | |
| β-strand | 822 | 1 | 9 |
| α-helix | 823-827 | 5 | |
| α-helix | 831-843 | 13 | |
| α-helix | 850-862 | 13 | |
Chain C: 37 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 5-16 | 12 | |
| α-helix | 33-41 | 9 | |
| α-helix | 177-198 | 22 | |
| α-helix | 204-212 | 9 | |
| α-helix | 220-229 | 10 | |
| α-helix | 254-274 | 21 | |
| α-helix | 289-299 | 11 | |
| β-strand | 312-313 | 2 | 21 |
| β-strand | 316-317 | 2 | 21 |
| α-helix | 318-328 | 11 | |
| α-helix | 331-340 | 10 | |
| α-helix | 347-352 | 6 | |
| α-helix | 369-374 | 6 | |
| α-helix | 375-379 | 5 | |
| α-helix | 385-395 | 11 | |
| α-helix | 410-420 | 11 | |
| α-helix | 437-446 | 10 | |
| α-helix | 449-452 | 4 | |
| α-helix | 462-469 | 8 | |
| α-helix | 472-479 | 8 | |
| α-helix | 486-498 | 13 | |
| α-helix | 528-539 | 12 | |
| α-helix | 544-552 | 9 | |
| α-helix | 553-556 | 4 | |
| α-helix | 562-577 | 16 | |
| α-helix | 580-584 | 5 | |
| β-strand | 585-586 | 2 | 22 |
| α-helix | 593 | 1 | |
| β-strand | 594-595 | 2 | 22 |
| α-helix | 597-601 | 5 | |
| α-helix | 606-619 | 14 | |
| α-helix | 624-632 | 9 | |
| α-helix | 635-646 | 12 | |
| α-helix | 663-675 | 13 | |
| β-strand | 679 | 1 | 24 |
| α-helix | 683-701 | 19 | |
| α-helix | 707-717 | 11 | |
| α-helix | 729-735 | 7 | |
| α-helix | 739-759 | 21 | |
| α-helix | 761-763 | 3 | |
| α-helix | 787-798 | 12 | |
| α-helix | 809-813 | 5 | |
Chains D, J and P: 64 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 15-23 | 9 | |
| α-helix | 41-45 | 5 | |
| α-helix | 47-51 | 5 | |
| α-helix | 62-68 | 7 | |
| β-strand | 71-72 | 2 | 25 |
| β-strand | 84-85 | 2 | 25 |
| α-helix | 88-101 | 14 | |
| α-helix | 105-114 | 10 | |
| α-helix | 130-152 | 23 | |
| α-helix | 165-172 | 8 | |
| α-helix | 182-193 | 12 | |
| α-helix | 197-205 | 9 | |
| α-helix | 211-237 | 27 | |
| α-helix | 243-254 | 12 | |
| α-helix | 268-280 | 13 | |
| α-helix | 305-316 | 12 | |
| α-helix | 317-319 | 3 | |
| α-helix | 324-340 | 17 | |
| α-helix | 344-349 | 6 | |
| α-helix | 352 | 1 | |
| α-helix | 353-357 | 5 | |
| α-helix | 358-365 | 8 | |
| α-helix | 368-377 | 10 | |
| α-helix | 385-402 | 18 | |
| α-helix | 404-417 | 14 | |
| α-helix | 430-435 | 6 | |
| α-helix | 438-450 | 13 | |
| α-helix | 461-464 | 4 | |
| α-helix | 494-503 | 10 | |
| α-helix | 507-520 | 14 | |
| α-helix | 524-535 | 12 | |
| α-helix | 555-572 | 18 | |
| α-helix | 592-609 | 18 | |
| α-helix | 614-619 | 6 | |
| α-helix | 626-635 | 10 | |
| α-helix | 643-653 | 11 | |
| α-helix | 661-669 | 9 | |
| α-helix | 687-697 | 11 | |
| α-helix | 701-715 | 15 | |
| α-helix | 733-742 | 10 | |
| α-helix | 755-774 | 20 | |
| α-helix | 778-782 | 5 | |
| α-helix | 793-798 | 6 | |
| α-helix | 802-810 | 9 | |
| α-helix | 815-824 | 10 | |
| α-helix | 840-862 | 23 | |
| α-helix | 863-867 | 5 | |
| α-helix | 868-869 | 2 | |
| α-helix | 883-886 | 4 | |
| α-helix | 893-904 | 12 | |
| α-helix | 910-923 | 14 | |
| α-helix | 1394-1409 | 16 | |
| α-helix | 1415-1432 | 18 | |
| α-helix | 1438-1448 | 11 | |
| β-strand | 1451 | 1 | 26 |
| α-helix | 1458-1516 | 59 | |
| α-helix | 1517-1521 | 5 | |
| α-helix | 1522-1538 | 17 | |
| α-helix | 1545-1564 | 20 | |
| α-helix | 1567-1575 | 9 | |
| α-helix | 1578-1585 | 8 | |
| α-helix | 1592-1594 | 3 | |
| α-helix | 1610-1632 | 23 | |
| α-helix | 1640-1651 | 12 | |
| α-helix | 1655-1659 | 5 | |
| α-helix | 1665-1683 | 19 | |
| α-helix | 1687-1690 | 4 | |
Chains E and W: 46 helices, 38 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-39 | 18 | |
| α-helix | 46-49 | 4 | |
| β-strand | 63-64 | 2 | 28 |
| β-strand | 81-88 | 8 | 29 |
| α-helix | 89-90 | 2 | |
| α-helix | 91-95 | 5 | |
| β-strand | 104-109 | 6 | 30 |
| β-strand | 114-119 | 6 | 30 |
| β-strand | 122-127 | 6 | 30 |
| β-strand | 134-137 | 4 | 30 |
| β-strand | 146-150 | 5 | 31 |
| α-helix | 151-153 | 3 | |
| β-strand | 163-168 | 6 | 31 |
| β-strand | 172-180 | 9 | 31 |
| β-strand | 198-202 | 5 | 31 |
| β-strand | 208-209 | 2 | 31 |
| β-strand | 215-220 | 6 | 32 |
| β-strand | 226-230 | 5 | 32 |
| β-strand | 236-238 | 3 | 32 |
| β-strand | 255-256 | 2 | 32 |
| β-strand | 279-285 | 7 | 33 |
| β-strand | 290-295 | 6 | 33 |
| β-strand | 300-306 | 7 | 33 |
| β-strand | 309-311 | 3 | 33 |
| β-strand | 317-318 | 2 | 33 |
| α-helix | 320-327 | 8 | |
| β-strand | 344-347 | 4 | 34 |
| β-strand | 356-361 | 6 | 34 |
| β-strand | 367-371 | 5 | 34 |
| β-strand | 375 | 1 | 35 |
| β-strand | 381 | 1 | 35 |
| β-strand | 386-391 | 6 | 34 |
| β-strand | 406 | 1 | 28 |
| β-strand | 411-413 | 3 | 28 |
| β-strand | 417-423 | 7 | 28 |
| β-strand | 429-436 | 8 | 28 |
| β-strand | 447-452 | 6 | 28 |
| β-strand | 460-463 | 4 | 29 |
| α-helix | 496-498 | 3 | |
| β-strand | 499-503 | 5 | 29 |
| β-strand | 507-513 | 7 | 29 |
| α-helix | 514-515 | 2 | |
| α-helix | 516-522 | 7 | |
| α-helix | 536-542 | 7 | |
| α-helix | 544-556 | 13 | |
| α-helix | 564-576 | 13 | |
| α-helix | 661-679 | 19 | |
| β-strand | 681 | 1 | 36 |
| β-strand | 683 | 1 | 37 |
| β-strand | 700 | 1 | 37 |
| α-helix | 704-723 | 20 | |
| α-helix | 725-728 | 4 | |
| α-helix | 770-800 | 31 | |
| α-helix | 803-810 | 8 | |
| α-helix | 815-819 | 5 | |
| β-strand | 822 | 1 | 36 |
| α-helix | 823-827 | 5 | |
| α-helix | 831-843 | 13 | |
| α-helix | 850-862 | 13 | |
| α-helix | 872-886 | 15 | |
| α-helix | 899-907 | 9 | |
| α-helix | 912-922 | 11 | |
| α-helix | 926-940 | 15 | |
| α-helix | 945-952 | 8 | |
| α-helix | 962-982 | 21 | |
| α-helix | 1016-1024 | 9 | |
| α-helix | 1035-1046 | 12 | |
| α-helix | 1049-1054 | 6 | |
| α-helix | 1060-1067 | 8 | |
| α-helix | 1077-1087 | 11 | |
| α-helix | 1091-1103 | 13 | |
| α-helix | 1111-1123 | 13 | |
| α-helix | 1140-1163 | 24 | |
| α-helix | 1173-1180 | 8 | |
| α-helix | 1185-1186 | 2 | |
| α-helix | 1187-1193 | 7 | |
| α-helix | 1199-1209 | 11 | |
| α-helix | 1214-1231 | 18 | |
| α-helix | 1237-1255 | 19 | |
| α-helix | 1264-1276 | 13 | |
| α-helix | 1284-1292 | 9 | |
| α-helix | 1296-1309 | 14 | |
| α-helix | 1321-1336 | 16 | |
| α-helix | 1356-1363 | 8 | |
Chains F, L, R and X: 14 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 129-140 | 12 | |
| β-strand | 154-157 | 4 | 38 |
| β-strand | 191-195 | 5 | 39 |
| α-helix | 199-204 | 6 | |
| α-helix | 206-216 | 11 | |
| β-strand | 224-232 | 9 | 39 |
| β-strand | 238-247 | 10 | 39 |
| β-strand | 253-255 | 3 | 39 |
| α-helix | 256-257 | 2 | |
| α-helix | 258-265 | 8 | |
| α-helix | 268-277 | 10 | |
| β-strand | 279-284 | 6 | 39 |
| α-helix | 291-297 | 7 | |
| α-helix | 306-315 | 10 | |
| β-strand | 323-326 | 4 | 38 |
| α-helix | 329-396 | 68 | |
| α-helix | 407-421 | 15 | |
| α-helix | 422-426 | 5 | |
| α-helix | 427-450 | 24 | |
| α-helix | 455-457 | 3 | |
| β-strand | 461 | 1 | 40 |
| α-helix | 463-490 | 28 | |
Chains G, M, S and Y: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 249-275 | 27 | |
| α-helix | 279-321 | 43 | |
| α-helix | 326-328 | 3 | |
| α-helix | 331-334 | 4 | |
| α-helix | 342-376 | 35 | |
| α-helix | 383-417 | 35 | |
Chains H, N, T and Z: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 335-405 | 71 | |
| α-helix | 411-422 | 12 | |
| α-helix | 432-460 | 29 | |
| α-helix | 471-498 | 28 | |
| α-helix | 499-501 | 3 | |
Chains I and U: 37 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 5-16 | 12 | |
| α-helix | 33-41 | 9 | |
| α-helix | 177-198 | 22 | |
| α-helix | 204-212 | 9 | |
| α-helix | 220-229 | 10 | |
| α-helix | 254-274 | 21 | |
| α-helix | 289-299 | 11 | |
| β-strand | 312-313 | 2 | 41 |
| β-strand | 316-317 | 2 | 41 |
| α-helix | 318-328 | 11 | |
| α-helix | 331-340 | 10 | |
| α-helix | 347-352 | 6 | |
| α-helix | 369-374 | 6 | |
| α-helix | 375-379 | 5 | |
| α-helix | 385-395 | 11 | |
| α-helix | 410-420 | 11 | |
| α-helix | 437-446 | 10 | |
| α-helix | 449-452 | 4 | |
| α-helix | 462-469 | 8 | |
| α-helix | 472-479 | 8 | |
| α-helix | 486-498 | 13 | |
| α-helix | 528-539 | 12 | |
| α-helix | 544-552 | 9 | |
| α-helix | 553-556 | 4 | |
| α-helix | 562-577 | 16 | |
| α-helix | 580-584 | 5 | |
| β-strand | 585-586 | 2 | 42 |
| α-helix | 593 | 1 | |
| β-strand | 594-595 | 2 | 42 |
| α-helix | 597-601 | 5 | |
| α-helix | 606-619 | 14 | |
| α-helix | 624-632 | 9 | |
| α-helix | 635-646 | 12 | |
| α-helix | 663-675 | 13 | |
| α-helix | 683-701 | 19 | |
| α-helix | 707-717 | 11 | |
| α-helix | 729-735 | 7 | |
| α-helix | 739-759 | 21 | |
| α-helix | 761-763 | 3 | |
| α-helix | 787-798 | 12 | |
| α-helix | 809-813 | 5 | |
4 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Nuclear pore complex protein NUP155 | A, B, E, K, Q, W | protein | 1391 | Homo sapiens | O75694 (AlphaFold model) |
| Nuclear pore complex protein NUP93 | C, I, O, U | protein | 819 | Homo sapiens | Q8N1F7 (AlphaFold model) |
| Nuclear pore complex protein NUP205 | D, J, P, V | protein | 2012 | Homo sapiens | Q92621 (AlphaFold model) |
| Nuclear pore complex protein NUP54 | F, L, R, X | protein | 507 | Homo sapiens | Q7Z3B4 (AlphaFold model) |
| Nuclear pore complex protein NUP58 | G, M, S, Y | protein | 599 | Homo sapiens | Q9BVL2 |
| Nuclear pore glycoprotein p62 | H, N, T, Z | protein | 522 | Homo sapiens | P37198 |
Sequence of entity 1 (A, B, E, K, Q, W), FASTA
>5IJN_1 NUCLEAR PORE COMPLEX PROTEIN NUP155 (chains A, B, E, K, Q, W)
MPSSLLGAAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGM
SDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTID
SDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSY
ANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAY
QAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGVI
QVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLA
VTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLM
AASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDH
IPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFK
LHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILGS
PVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYS
GKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEF
LDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQA
IQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIAS
LINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRES
LKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIV
GLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHF
EQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDL
LWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEF
LHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAE
CKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPR
FFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKP
LHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNF
KSLQAKLERLH
Sequence of entity 2 (C, I, O, U), FASTA
>5IJN_2 NUCLEAR PORE COMPLEX PROTEIN NUP93 (chains C, I, O, U)
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKA
SVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKR
TFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDN
IEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKSISDMWTMVKQMTDVLLTPATD
ALKNRSSVEVRMEFVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIK
LPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKD
RRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQ
VCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAVAFLF
RMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCLRRLNFVRLLMLYTRKFE
STDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDK
FTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNK
ERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLV
PLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSSRPQRVIED
RDSQLRSQARTLITFAGMIPYRTSGDTNARLVQMEVLMN
Sequence of entity 3 (D, J, P, V), FASTA
>5IJN_3 NUCLEAR PORE COMPLEX PROTEIN NUP205 (chains D, J, P, V)
MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKN
VQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQP
HFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQ
GLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSP
LGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPL
LTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMA
ELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARM
IHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYL
GVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSS
HVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAF
LQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIA
ASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFP
SNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQL
EDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKK
HLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIA
RYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDA
EEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNL
QDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPT
MRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLL
HLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQ
LDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEIS
TVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHD
KILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPP
EENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDT
LEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALL
DRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFL
TRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQIL
LPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGII
SKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEG
DKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQ
APVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMP
AGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDS
QDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLL
DIEGLYSKVRSRYSFIQALVRRIRGLLRISRN
Sequence of entity 4 (F, L, R, X), FASTA
>5IJN_4 NUCLEAR PORE COMPLEX PROTEIN NUP54 (chains F, L, R, X)
MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG
FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT
ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC
MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV
VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP
PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE
LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE
LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI
IKDDLEDIKLVEHGLNETIHIRGGVFS
Sequence of entity 5 (G, M, S, Y), FASTA
>5IJN_5 NUCLEAR PORE COMPLEX PROTEIN NUP58 (chains G, M, S, Y)
MSTGFSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATTSAPS
SGFGTGLFGSKPATGFTLGGTNTGIATTITTGLTLGTPATTSAATTGFSLGFNKPAASAT
PFALPITSTSASGLTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLGGALAGLGG
SLFQSTNTGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDKKSDKTGTRPEDSK
ALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAANG
IQRNTLNIDKLKIETAQELKNAEIALRTQKTPPGLQHEYAAPADYFRILVQQFEVQLQQY
RQQIEELENHLATQANNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLKEQYLGY
RKMFLGDAVDVFETRRAEAKKWQNTPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGP
QPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCSTTGASTFGFGTTNKPSGS
LSAGFGSSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGGQLLQLKKPPAGNKRGKR
Sequence of entity 6 (H, N, T, Z), FASTA
>5IJN_6 Nuclear pore glycoprotein p62 (chains H, N, T, Z)
MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLF
SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN
LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA
QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC
TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPA
GIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNA
WDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGT
IYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNA
HMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD
Primary citation
Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Kosinski, J., Mosalaganti, S., von Appen, A. et al. Science (2016) 352:363-365. DOI 10.1126/science.aaf0643 · PubMed
Other PDB entries of the same protein (UniProt O75694 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7R1Y 3.0 Å, cryoEM structure of human Nup155 (residues 19-981)
- 7EYE 5.1 Å, Cryo-EM (SPA) structure of Nup155 N-terminus (19-863) at 5.1 Angstrom resolution
- 7EYF 5.3 Å, Cryo-EM (SPA) structure of human Nup155 C-terminus (864-1337) at 5.3 Angstroms resolution
- 7EYQ 5.4 Å, Cryo-EM (SPA) structure of human Nup155 Longer N-terminus (19-1069) at 5.4 Angstrom…
- 7R5K 12.0 Å, Human nuclear pore complex (constricted)
- 5IJO 21.4 Å, Alternative composite structure of the inner ring of the human nuclear pore complex (16…
- 5A9Q 23.0 Å, Human nuclear pore complex
- 7PER 35.0 Å, Model of the inner ring of the human nuclear pore complex
- 7R5J 50.0 Å, Human nuclear pore complex (dilated)
- 9A25 Molecular assembly pathway of the human Nuclear Pore Complex after cell division
- 9A8T Integrative spatiotemporal modeling of biomolecular processes: application to the…
Browse structure collections
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