Q12146: DNA replication complex GINS protein PSF3 (PSF3)

DNA replication complex GINS protein PSF3 (PSF3) is a 194-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12146.

Gene
PSF3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
194 residues
Mean pLDDT
82.8
Model
AF-Q12146-F1 v6
Model created
1 Aug 2025
PDB structures
29

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Model confidence (pLDDT)

The mean pLDDT of this model is 82.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate39%
70 to 90Confident: backbone generally right43%
50 to 70Low: treat with caution16%
Below 50Very low: often disordered regions3%

What pLDDT means and how to read it

Function

Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery

Subunit structure

Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8KG6EM3.07 ÅC=1-194
7PMKEM3.2 ÅC=1-194
9E2YEM3.2 ÅC=1-194
7QHSEM3.3 ÅC=1-194
9E2WEM3.3 ÅC=1-194
7Z13EM3.4 ÅC/J=1-194
8B9AEM3.5 ÅE=1-194
8B9BEM3.5 ÅE=1-194
9E2XEM3.5 ÅC=1-194
3JC6EM3.7 ÅC=1-194
6SKLEM3.7 ÅC=1-194
8P63EM3.7 ÅC=1-194
8XGCEM3.7 ÅC=1-194
6PTJEM3.8 ÅC=1-194
6U0MEM3.9 ÅC=3-193
8P5EEM3.9 ÅC=1-194
8P62EM3.9 ÅC=1-194
8W7MEM4.12 ÅC=1-194
8KG8EM4.23 ÅC=1-194
8KG9EM4.52 ÅC=1-194

Showing 20 of 29 experimental structures (best resolution first).

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