Motor proteins and the cytoskeleton

The cytoskeleton is a network of protein filaments that gives cells their shape and acts as tracks for transport. Motor proteins such as myosin, kinesin and dynein burn ATP to walk along these tracks, contracting muscles and carrying cargo. This collection shows actin, tubulin and the motors that move along them.

Open Actin bound to DNase I in 3D

19 structures

• Actin bound to DNase I1ATN
  The first atomic structure of actin, solved as a complex with DNase I.
• Uncomplexed actin1J6Z
• Profilin bound to beta-actin2BTF
• Actin filament (F-actin)3J8I
• Tubulin alpha-beta dimer1TUB
• Tubulin with taxol1JFF
  The cancer drug taxol (paclitaxel) stabilizes microtubules.
• Microtubule6DPU
• Chicken muscle myosin subfragment-1 (the motor head)2MYS
• Dictyostelium myosin motor domain with ADP1MMA
• Scallop myosin S1 in the pre-power stroke state1QVI
• Human cytoplasmic actomyosin complex5JLH
• Tropomyosin1C1G
• Human cardiac thin filament6KN8
• Kinesin dimer3KIN
• Human kinesin motor domain1BG2
• Ncd, a minus-end-directed kinesin2NCD
• Dynein motor domain3VKH
• Keratin 5 and 14 coiled-coil segment3TNU
• Human beta-actin (AlphaFold)P60709 (AlphaFold)

More collections

• Hemoglobin and oxygen transport
• Insulin and hormones
• SARS-CoV-2 and COVID-19
• DNA and RNA
• Enzymes: how proteins speed up chemistry
• Antibodies and the immune system
• Membrane proteins and transporters
• AlphaFold highlights
• Photosynthesis
• Ion channels
• GPCRs and cell signaling
• Kinases and cancer drug targets
• Viruses
• The ribosome and protein synthesis
• CRISPR and genome editing
• Fluorescent and glowing proteins
• Neurotransmission and the synapse
• Blood clotting
• Drugs bound to their targets
• Classic small proteins for teaching
• Metabolism and cellular energy
• Protein folding, misfolding and amyloid
• Toxins and how they work